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Monitoring of a progressive functional dopaminergic deficit in the A53T-AAV synuclein rats by combining 6-[18F]fluoro-L-m-tyrosine imaging and motor performances analysis Becker, Guillaume; Michel, Anne; Bahri, Mohamed Ali; Mairet-Coello, Georges; Lemaire, Christian; Deprez, Tania; Freyssin, Aline; Jacquin, Lucas; Hustadt, Fabian; De Wolf, Catherine; Caruso, Melina; Frequin, Jean-Marie; Gillent, Eric; Bezard, Erwan; Garraux, Gaetan; Luxen, Andre; Citron, Martin; Downey, Patrick; Plenevaux, Alain 分享 收藏
Current directions in tau research: Highlights from Tau 2020 Sexton, Claire; Snyder, Heather; Beher, Dirk; Boxer, Adam L.; Brannelly, Pat; Brion, Jean-Pierre; Buee, Luc; Cacace, Angela M.; Chetelat, Gael; Citron, Martin; DeVos, Sarah L.; Diaz, Kristophe; Feldman, Howard H.; Frost, Bess; Goate, Alison M.; Gold, Michael; Hyman, Bradley; Johnson, Keith; Karch, Celeste M.; Kerwin, Diana R.; Koroshetz, Walter J.; Litvan, Irene; Morris, Huw R.; Mummery, Catherine J.; Mutamba, James; Patterson, Marc C.; Quiroz, Yakeel T.; Rabinovici, Gil D.; Rommel, Amy; Shulman, Melanie B.; Toledo-Sherman, Leticia M.; Weninger, Stacie; Wildsmith, Kristin R.; Worley, Susan L.; Carrillo, Maria C. 分享 收藏
Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody Albert, Marie; Mairet-Coello, Georges; Danis, Clement; Lieger, Sarah; Caillierez, Raphaelle; Carrier, Sebastien; Skrobala, Emilie; Landrieu, Isabelle; Michel, Anne; Schmitt, Mathieu; Citron, Martin; Downey, Patrick; Courade, Jean-Philippe; Buee, Luc; Colin, Morvane 分享 收藏
Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau Courade, Jean-Philippe; Angers, Rachel; Mairet-Coello, Georges; Pacico, Nathalie; Tyson, Kerry; Lightwood, Daniel; Munro, Rebecca; McMillan, David; Griffin, Robert; Baker, Terry; Starkie, Dale; Nan, Ruodan; Westwood, Marta; Mushikiwabo, Marie-Laetitia; Jung, Sophie; Odede, Geofrey; Sweeney, Berni; Popplewell, Andrew; Burgess, Gillian; Downey, Patrick; Citron, Martin 分享 收藏
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Establishing the Relationship between In Vitro Potency, Pharmacokinetic, and Pharmacodynamic Parameters in a Series of Orally Available, Hydroxyethylamine-Derived β-Secretase Inhibitors Wood, Stephen; Wen, Paul H.; Zhang, Jianhua; Zhu, Li; Luo, Yi; Babu-Khan, Safura; Chen, Kui; Pham, Roger; Esmay, Joel; Dineen, Thomas A.; Kaller, Matthew R.; Weiss, Matthew M.; Hitchcock, Stephen A.; Citron, Martin; Zhong, Wenge; Hickman, Dean; Williamson, Toni 分享 收藏
A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase Kaller, Matthew R.; Harried, Scott S.; Albrecht, Brian; Amarante, Patricia; Babu-Khan, Safura; Bartberger, Michael D.; Brown, James; Brown, Ryan; Chen, Kui; Cheng, Yuan; Citron, Martin; Croghan, Michael D.; Graceffa, Russell; Hickman, Dean; Judd, Ted; Kriemen, Chuck; La, Daniel; Li, Vivian; Lopez, Patricia; Luo, Yi; Masse, Craig; Monenschein, Holger; Nguyen, Thomas; Pennington, Lewis D.; Miguel, Tisha San; Sickmier, E. Allen; Wahl, Robert C.; Weiss, Matthew M.; Wen, Paul H.; Williamson, Toni; Wood, Stephen; Xue, May; Yang, Bryant; Zhang, Jianhua; Patel, Vinod; Zhong, Wenge; Hitchcock, Stephen 分享 收藏
Design and Preparation of a Potent Series of Hydroxyethylamine Containing β-Secretase Inhibitors That Demonstrate Robust Reduction of Central β-Amyloid Weiss, Matthew M.; Williamson, Toni; Babu-Khan, Safura; Bartberger, Michael D.; Brown, James; Chen, Kui; Chen, Yuan; Citron, Martin; Croghan, Michael D.; Dineen, Thomas A.; Esmay, Joel; Graceffa, Russell F.; Harried, Scott S.; Hickman, Dean; Hitchcock, Stephen A.; Horne, Daniel B.; Huang, Hongbing; Imbeah-Ampiah, Ronke; Judd, Ted; Kaller, Matthew R.; Kreiman, Charles R.; La, Daniel S.; Lopez, Patricia; Louie, Steven; Monenschein, Holger; Nguyen, Thomas T.; Pennington, Lewis D.; Rattan, Claire; Miguel, Tisha San; Sickmier, E. Allen; Wahl, Robert C.; Wen, Paul H.; Wood, Stephen; Xue, Qiufen; Yang, Bryant H.; Patel, Vinod F.; Zhong, Wenge 分享 收藏
Design and Synthesis of Potent, Orally Efficacious Hydroxyethylamine Derived β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors Dineen, Thomas A.; Weiss, Matthew M.; Williamson, Toni; Acton, Paul; Babu-Khan, Safura; Bartberger, Michael D.; Brown, James; Chen, Kui; Cheng, Yuan; Citron, Martin; Crogan, Michael D.; Dunn, Robert T., II; Esmay, Joel; Graceffa, Russell F.; Harriedt, Scott S.; Hickman, Dean; Hitchcock, Stephen A.; Horne, Daniel B.; Huang, Hongbing; Imbeah-Ampiah, Ronke; Judd, Ted; Kaller, Matthew R.; Kreiman, Charles R.; La, Daniel S.; Li, Vivian; Lopez, Patricia; Louie, Steven; Monenschein, Holger; Nguyen, Thomas T.; Pennington, Lewis D.; Miguel, Tisha Sin; Sickmier, E. Allen; Vargas, Hugo M.; Wahl, Robert C.; Wen, Paul H.; Whittington, Douglas A.; Wood, Stephen; Xue, Qiufen; Yang, Bryant H.; Patel, Vinod F.; Zhong, Wenge 分享 收藏
Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models REDUCTION OF TAU PATHOLOGY AND DELAY OF DISEASE PROGRESSION Chai, Xiyun; Wu, Su; Murray, Tracey K.; Kinley, Robert; Cella, Claire V.; Sims, Helen; Buckner, Nicola; Hanmer, Jenna; Davies, Peter; O'Neill, Michael J.; Hutton, Michael L.; Citron, Martin 分享 收藏
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Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity Ma, Huifang; Lesne, Sylvain; Kotilinek, Linda; Steidl-Nichols, Jill V.; Sherman, Mathew; Younkin, Linda; Younkin, Steven; Forster, Colleen; Sergeant, Nicolas; Delacourte, Andre; Vassar, Robert; Citron, Martin; Kofuji, Paulo; Boland, Linda M.; Ashe, Karen H. 分享 收藏
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