David Siegel - Publications, H-index & Citations

David Siegel

university of colorado anschutz medical campus

59H指数

276论文数

1.2W被引数

收录论文 74

发表时间

Indolequinone inhibitors of NRH:quinone oxidoreductase 2. Further structure-activity relationships NRH:quinone oxidoreductase 2 的吲哚醌抑制剂。进一步的构效关系。

Bioorganic & Medicinal Chemistry

IF3

2025-10-30

OAAI

Tatiana A. Dias; David Siegel; David Ross; Christopher J. Moody

Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma C19-Position取代格尔德霉素衍生物靶向NRF2-NQO1-activated食管鳞癌的抗癌作用

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2024-12-24

OAAI

Oshikiri, Hiroyuki; Taguchi, Keiko; Hirose, Wataru; Taniyama, Yusuke; Kamei, Takashi; Siegel, David; Ross, David; Kitson, Russell R. A.; Baird, Liam; Yamamoto, Masayuki

Geldanamycin, a Naturally Occurring Inhibitor of Hsp90 and a Lead Compound for Medicinal Chemistry

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-10-03

OAAI

Kitson, Russell R. A.; Kitsonova, Dominika; Siegel, David; Ross, David; Moody, Christopher J.

Antileukemic potential of methylated indolequinone MAC681 through immunogenic necroptosis and PARP1 degradation

BIOMARKER RESEARCH

IF11.5

2024-05-04

OAAI

Orlikova-Boyer, Barbora; Lorant, Anne; Gajulapalli, Sruthi Reddy; Cerella, Claudia; Schnekenburger, Michael; Lee, Jin-Young; Paik, Ji Yeon; Lee, Yejin; Siegel, David; Ross, David; Han, Byung Woo; Nguyen, Thi Kim Yen; Christov, Christo; Kang, Hyoung Jin; Dicato, Mario; Diederich, Marc

FAD-deficient P187S mutation of NAD(P)H:quinone oxidoreductase 1 (NQO1*2) binds and accelerates β-amyloid aggregation

BIOSCIENCE REPORTS

IF4.7

2022-11-14

OAAI

Panja, Sudipta; Siegel, David; Camandola, Simonetta; de Cabo, Rafael; Ross, David; Mallela, Krishna M. G.

Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva

BONE

IF3.6

2021-09-01

PREAI

Kaplan, Frederick S.; Teachey, David T.; Andolina, Jeffrey R.; Siegel, David M.; Mancilla, Edna E.; Hsiao, Edward C.; Al Mukaddam, Mona; Rocke, David M.; Pignolo, Robert J.

NQO1 protects obese mice through improvements in glucose and lipid metabolism

NPJ AGING AND MECHANISMS OF DISEASE

IF5.4

2020-11-19

OAAI

Di Francesco, Andrea; Choi, Youngshim; Bernier, Michel; Zhang, Yingchun; Diaz-Ruiz, Alberto; Aon, Miguel A.; Kalafut, Krystle; Ehrlich, Margaux R.; Murt, Kelsey; Ali, Ahmed; Pearson, Kevin J.; Levan, Sophie; Preston, Joshua D.; Martin-Montalvo, Alejandro; Martindale, Jennifer L.; Abdelmohsen, Kotb; Michel, Cole R.; Willmes, Diana M.; Henke, Christine; Navas, Placido; Villalba, Jose Manuel; Siegel, David; Gorospe, Myriam; Fritz, Kristofer; Biswal, Shyam; Ross, David; de Cabo, Rafael

Access to Mohs micrographic surgery through the Veterans Choice Program of the United States Department of Veterans Affairs

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

IF11.8

2020-09-01

OAAI

Siegel, David; Joo, Jayne S.; Cortez, Rachel A.; Furlong, Theresa A.; Isseroff, R. Rivkah

Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome (vol 12, pg 110, 2010)

CURRENT ATHEROSCLEROSIS REPORTS

IF5.2

2019-01-25

OAAI

Devaraj, Sridevi; Valleggi, Simona; Siegel, David; Jialal, Ishwarlal

Statin Therapy in Metabolic Syndrome and Hypertension Post-JUPITER: What is the Value of CRP? (vol 13, 31, 2011)

CURRENT ATHEROSCLEROSIS REPORTS

IF5.2

2019-01-21

OAAI

Devaraj, Sridevi; Siegel, David; Jialal, Ishwarlal

Chronic Back Pain and a Bulge

JAMA SURGERY

IF14.9

2018-12-01

PREAI

Nielsen, Carrie; Bigelow, Roger; Siegel, David

Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases

BONE

IF3.6

2018-04-01

PREAI

Kaplan, Frederick S.; Andolina, Jeffrey R.; Adamson, Peter C.; Teachey, David T.; Finklestein, Jerry Z.; Ebb, David H.; Whitehead, Benjamin; Jacobs, Benjamin; Siegel, David M.; Keen, Richard; Hsiao, Edward; Pignolo, Robert J.

Inflammation, Atherosclerosis, and Psoriasis (vol 44, pg 194, 2013)

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

IF11.3

2018-03-19

OAAI

Siegel, David; Devaraj, Sridevi; Mitra, Anupam; Raychaudhuri, Siba P.; Raychaudhuri, Smriti K.; Jialal, Ishwarlal

Review: In hypertension, BP self-monitoring interventions improve BP levels and BP control at 12 months

ANNALS OF INTERNAL MEDICINE

IF15.2

2018-02-01

PREAI

Siegel, David

Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch

FRONTIERS IN PHYSIOLOGY

IF3.4

2017-08-24

260

OAAI

Ross, David; Siegel, David

Novel RNA-binding activity of NQ01 promotes SERPINA1 mRNA translation

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2016-10-01

OAAI

Di Francesco, Andrea; Di Germanio, Clara; Panda, Amaresh C.; Huynh, Phu; Peaden, Robert; Navas-Enamorado, Ignacio; Bastian, Paul; Lehrmann, Elin; Diaz-Ruiz, Alberto; Ross, David; Siegel, David; Martindale, Jennifer L.; Bernier, Michel; Gorospe, Myriam; Abdelmohsen, Kotb; de Cabo, Rafael

A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity

MOLECULAR PHARMACOLOGY

IF3

2015-12-01

OAAI

Xiong, Rui; Zhou, Wenbo; Siegel, David; Kitson, Russell R. A.; Freed, Curt R.; Moody, Christopher J.; Ross, David

In uncontrolled hypertension, a pharmacist-prescribing intervention reduced blood pressure at 6 months

ANNALS OF INTERNAL MEDICINE

IF15.2

2015-11-01

PREAI

Siegel, David

Effect of 19-substituted benzoquinone ansamycin Hsp90 inhibitors on Hsp90/Cdc37/co-chaperone complexes and casein kinase 2 (CK2) activity

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Chang, Chuan-Hsin; Rossi, David; Siegel, David; Moody, Christopher J.; Kitson, Russell

19-Substituted benzoquinone ansamycins. Hsp90 inhibitors with decreased off-target toxicity

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Chang, Chuan-Hsin; Drechsel, Derek A.; Kitson, Russell R. A.; Siegel, David; You, Qiang; Backos, Donald S.; Ju, Cynthia; Moody, Christopher J.; Ross, David

研究方向