Luke Isbel - Publications, H-index & Citations

Luke Isbel

Adelaide University

14H指数

41论文数

1.1K被引数

收录论文 14

发表时间

DesignMaster: A Multi-Conditional Diffusion Framework for Rational PROTAC Design DesignMaster：一种用于理性PROTAC设计的多条件扩散框架

Bioinformatics

IF5.4

2026-09-24

OAAI

Binze Shi; Yi Hao; Jie Liu; Tong Pan; Luke Isbel; Michael Roy; Ashley P Ng; Xuequn Shang; Fuyi Li; null; null

Chromatin-dependent motif syntax defines differentiation trajectories 染色质依赖性基序句法定义了分化轨迹

Molecular Cell

IF16.6

2025-08-07

OAAI

Sevi Durdu; Murat Iskar; Luke Isbel; Leslie Hoerner; Christiane Wirbelauer; Lukas Burger; Daniel Hess; Vytautas Iesmantavicius; Dirk Schübeler

Nucleosomes specify co-factor access to p53 核小体规定了辅因子对p53的访问

Molecular Cell

IF16.6

2025-07-25

PREAI

Deyasini Chakraborty; Colby R. Sandate; Luke Isbel; Georg Kempf; Joscha Weiss; Simone Cavadini; Lukas Kater; Jan Seebacher; Zuzanna Kozicka; Lisa Stoos; Ralph S. Grand; Dirk Schübeler; Alicia K. Michael; Nicolas H. Thomä

Accurate PROTAC-targeted degradation prediction with DegradeMaster 刘, J.; Roy, M.J.; Isbel, L.; Li, F. 使用DegradeMaster进行准确的PROTAC靶向降解预测. Bioinformatics 2025, 41, i342–i351. [Google Scholar] [CrossRef]

BIOINFORMATICS

IF5.4

2025-07-01

OAAI

Liu, Jie; Roy, Michael J.; Isbel, Luke; Li, Fuyi

Readout of histone methylation by Trim24 locally restricts chromatin opening by p53

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-06-29

OAAI

Isbel, Luke; Iskar, Murat; Durdu, Sevi; Weiss, Joscha; Grand, Ralph S.; Hietter-Pfeiffer, Eric; Kozicka, Zuzanna; Michael, Alicia K.; Burger, Lukas; Thomae, Nicolas H.; Schubeler, Dirk

ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers

NATURE CELL BIOLOGY

IF19.1

2023-01-05

OAAI

Yelagandula, Ramesh; Stecher, Karin; Novatchkova, Maria; Michetti, Luca; Michlits, Georg; Wang, Jingkui; Hofbauer, Pablo; Vainorius, Gintautas; Pribitzer, Carina; Isbel, Luke; Mendjan, Sasha; Schuebeler, Dirk; Elling, Ulrich; Brennecke, Julius; Bell, Oliver

Generating specificity in genome regulation through transcription factor sensitivity to chromatin 通过转录因子对染色质的敏感性在基因组调控中产生特异性

NATURE REVIEWS GENETICS

IF52

2022-07-12

PREAI

Isbel, Luke; Grand, Ralph S.; Schubeler, Dirk

CG dinucleotides enhance promoter activity independent of DNA methylation

GENOME RESEARCH

IF5.5

2019-02-01

OAAI

Hartl, Dominik; Krebs, Arnaud R.; Grand, Ralph S.; Baubect, Tuncay; Isbel, Luke; Wirbelauer, Christiane; Burger, Lukas; Schuebeler, Dirk

Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse

ELIFE

IF0

2016-07-13

OAAI

Isbel, Luke; Prokopuk, Lexie; Wu, Haoyu; Daxinger, Lucia; Oey, Harald; Spurling, Alex; Lawther, Adam J.; Hale, Matthew W.; Whitelaw, Emma

Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype

SCIENTIFIC REPORTS

IF3.9

2016-04-26

OAAI

Daxinger, Lucia; Oey, Harald; Isbel, Luke; Whitelaw, Nadia C.; Youngson, Neil A.; Spurling, Alex; Vonk, Kelly K. D.; Whitelaw, Emma

Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions 近交小鼠同窝小鼠的遗传和表观遗传变异: 个体间差异甲基化区域的鉴定

EPIGENETICS & CHROMATIN

IF3.5

2015-12-12

OAAI

Oey, Harald; Isbel, Luke; Hickey, Peter; Ebaid, Basant; Whitelaw, Emma

Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome

PLOS GENETICS

IF3.7

2015-12-01

OAAI

Isbel, Luke; Srivastava, Rahul; Oey, Harald; Spurling, Alex; Daxinger, Lucia; Puthalakath, Hamsa; Whitelaw, Emma

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

GENOME BIOLOGY

IF9.4

2013-09-11

OAAI

Daxinger, Lucia; Harten, Sarah K.; Oey, Harald; Epp, Trevor; Isbel, Luke; Huang, Edward; Whitelaw, Nadia; Apedaile, Anwyn; Sorolla, Anabel; Yong, Joan; Bharti, Vandhana; Sutton, Joanne; Ashe, Alyson; Pang, Zhenyi; Wallace, Nathan; Gerhardt, Daniel J.; Blewitt, Marnie E.; Jeddeloh, Jeffrey A.; Whitelaw, Emma

Endogenous retroviruses in mammals: An emerging picture of how ERVs modify expression of adjacent genes

BIOESSAYS

IF2.7

2012-06-26

PREAI

Isbel, Luke; Whitelaw, Emma

研究方向