Uwe Konietzko - Publications, H-index & Citations

Uwe Konietzko

Institute for Regenerative Medicine

25H指数

59论文数

4.1K被引数

收录论文 21

发表时间

Increased levels of GFAP and purinergic P2X7 receptor in Alzheimer’s disease brain are associated with Aβ, tau pathologies and synaptic loss 阿尔茨海默病 brains 中 GFAP 和嘌呤能 P2X7 受体的水平升高与 Aβ、tau 病理及突触丢失相关。

Alzheimer's Research & Therapy

IF7.6

2025-11-25

OAAI

Cinzia A. Maschio; Oscar Moreno; Junlong Wang; Upasana Maheshwari; Annika Keller; Uwe Konietzko; Daniel Razansky; Agneta Nordberg; Axel Rominger; Christoph Hock; Jordi Llop; Roger M. Nitsch; Ruiqing Ni

Reduced synaptic vesicle protein 2A in extracellular vesicles and brains of Alzheimer’s disease: associations with Aβ, tau, synaptic proteins and APOE ε4 阿尔茨海默病中细胞外囊泡和脑内的突触小泡蛋白2A减少：与Aβ、tau、突触蛋白和APOE ε4的关联

Translational Neurodegeneration

IF15.2

2025-09-26

OAAI

Jana Nussbaumer; Aatmika Barve; Valentin Zufferey; Jeanne Espourteille; Tunahan Kirabali; Uwe Konietzko; Daniel Razansky; Axel Rominger; Agneta Nordberg; Luc Buée; Morvane Colin; Roger M. Nitsch; Christoph Hock; Kevin Richetin; Ruiqing Ni

Spiral volumetric optoacoustic tomography of reduced oxygen saturation in the spinal cord of M83 mouse model of Parkinson's disease

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2024-10-09

OAAI

Combes, Benjamin F.; Kalva, Sandeep Kumar; Benveniste, Pierre-Louis; Tournant, Agathe; Law, Man Hoi; Newton, Joshua; Kruger, Maik; Weber, Rebecca Z.; Dias, Ines; Noain, Daniela; Dean-Ben, Xose Luis; Konietzko, Uwe; Baumann, Christian R.; Gillberg, Per-Goeran; Hock, Christoph; Nitsch, Roger M.; Cohen-Adad, Julien; Razansky, Daniel; Ni, Ruiqing

Aquaporin 4 is differentially increased and dislocated in association with tau and amyloid-beta

LIFE SCIENCES

IF5.1

2023-05-01

OAAI

Kecheliev, Vasil; Boss, Leo; Maheshwari, Upasana; Konietzko, Uwe; Keller, Annika; Razansky, Daniel; Nitsch, Roger M.; Klohs, Jan; Ni, Ruiqing

Non-invasive imaging of tau-targeted probe uptake by whole brain multi-spectral optoacoustic tomography

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2022-02-07

OAAI

Vagenknecht, Patrick; Luzgin, Artur; Ono, Maiko; Ji, Bin; Higuchi, Makoto; Noain, Daniela; Maschio, Cinzia A.; Sobek, Jens; Chen, Zhenyue; Konietzko, Uwe; Gerez, Juan A.; Riek, Roland; Razansky, Daniel; Klohs, Jan; Nitsch, Roger M.; Dean-Ben, Xose Luis; Ni, Ruiqing

Fe65 is the sole member of its family that mediates transcription regulated by the amyloid precursor protein

JOURNAL OF CELL SCIENCE

IF3.6

2020-09-08

OAAI

Probst, Sabine; Kruger, Maik; Kagi, Larissa; Thoni, Sarina; Schuppli, Daniel; Nitsch, Roger M.; Konietzko, Uwe

Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2017-05-11

OAAI

Feilen, Lukas P.; Haubrich, Kevin; Strecker, Paul; Probst, Sabine; Eggert, Simone; Stier, Gunter; Sinning, Irmgard; Konietzko, Uwe; Kins, Stefan; Simon, Bernd; Wild, Klemens

RanBP9 Modulates AICD Localization and Transcriptional Activity via Direct Interaction with Tip60

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2014-10-10

PREAI

Dominguesa, Sara C.; Konietzko, Uwe; Henriques, Ana Gabriela; Rebelo, Sandra; Fardilha, Margarida; Nishitani, Hideo; Nitsch, Roger M.; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss

CELL DEATH & DISEASE

IF9.6

2013-04-25

116

OAAI

Tackenberg, C.; Grinschgl, S.; Trutzel, A.; Santuccione, A. C.; Frey, M. C.; Konietzko, U.; Grimm, J.; Brandt, R.; Nitsch, R. M.

Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation 表达大阪a β 内APP突变的小鼠中细胞内纤维状低聚物的早期积累和晚期嗜血淀粉样血管病

TRANSLATIONAL PSYCHIATRY

IF6.2

2012-11-13

OAAI

Kulic, L.; McAfoose, J.; Welt, T.; Tackenberg, C.; Spaeni, C.; Wirth, F.; Finder, V.; Konietzko, U.; Giese, M.; Eckert, A.; Noriaki, K.; Shimizu, T.; Murakami, K.; Irie, K.; Rasool, S.; Glabe, C.; Hock, C.; Nitsch, R. M.

Interactome of the Amyloid Precursor Protein APP in Brain Reveals a Protein Network Involved in Synaptic Vesicle Turnover and a Close Association with Synaptotagmin-1

JOURNAL OF PROTEOME RESEARCH

IF3.6

2012-07-19

PREAI

Kohli, Bernhard M.; Pflieger, Delphine; Mueller, Lukas N.; Carbonetti, Giovanni; Aebersold, Ruedi; Nitsch, Roger M.; Konietzko, Uwe

Co-Localization of Reelin and Proteolytic AβPP Fragments in Hippocampal Plaques in Aged Wild-Type Mice

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2010-03-11

PREAI

Doehner, Jana; Madhusudan, Amrita; Konietzko, Uwe; Fritschy, Jean-Marc; Knuesel, Irene

Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories

NEUROBIOLOGY OF AGING

IF3.5

2010-01-01

OAAI

Konietzko, Uwe; Goodger, Zoe V.; Meyer, Michelle; Kohli, Bernhard M.; Bosset, Jerome; Lahiri, Debomoy K.; Nitsch, Roger M.

Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway

JOURNAL OF CELL SCIENCE

IF3.6

2009-10-15

121

PREAI

Goodger, Zoe V.; Rajendran, Lawrence; Trutzel, Annette; Kohli, Bernhard M.; Nitsch, Roger M.; Konietzko, Uwe

ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2009-04-01

183

OAAI

Tousseyn, Thomas; Thathiah, Amantha; Jorissen, Ellen; Raemaekers, Tim; Konietzko, Uwe; Reiss, Karina; Maes, Elke; Snellinx, An; Serneels, Lutgarde; Nyabi, Omar; Annaert, Wim; Saftig, Paul; Hartmann, Dieter; De Strooper, Bart

Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice

NEUROBIOLOGY OF AGING

IF3.5

2007-09-01

244

PREAI

Knobloch, Marlen; Konietzko, Uwe; Krebs, Danielle C.; Nitsch, Roger M.

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor

JOURNAL OF CELL SCIENCE

IF3.6

2004-09-01

338

OAAI

von Rotz, RC; Kohli, BM; Bosset, J; Meier, M; Suzuki, T; Nitsch, RM; Konietzko, U

Antibodies against β-amyloid slow cognitive decline in Alzheimer's disease

NEURON

IF15

2003-05-01

796

OAAI

Hock, C; Konietzko, U; Streffer, JR; Tracy, J; Signorell, A; Müller-Tillmanns, B; Lemke, U; Henke, K; Moritz, E; Garcia, E; Wollmer, MA; Umbricht, D; de Quervain, DJF; Hofmann, M; Maddalena, A; Papassotiropoulos, A; Nitsch, RM

Generation of antibodies specific for β-amyloid by vaccination of patients with Alzheimer disease

NATURE MEDICINE

IF50

2002-10-15

282

PREAI

Hock, C; Konietzko, U; Papassotiropoulos, A; Wollmer, A; Streffer, J; von Rotz, RC; Davey, G; Moritz, E; Nitsch, RM

Pim kinase expression is induced by LTP stimulation and required for the consolidation of enduring LTP

EMBO JOURNAL

IF8.3

1999-06-15

OAAI

Konietzko, U; Kauselmann, G; Scafidi, J; Staubli, U; Mikkers, H; Berns, A; Schweizer, M; Waltereit, R; Kuhl, D

研究方向