Bradley M. Dickson - Publications, H-index & Citations

Bradley M. Dickson

van andel institute

21H指数

85论文数

1.8K被引数

收录论文 34

发表时间

Thermodynamic Insights into the WT and Y220C TP53 DBDs Reveal that the Oncogenic Y220C Variant is a Loss-of-Function Mutation for Zn2+-Binding at Physiological Temperature 热力学分析揭示野生型与Y220C TP53 DBDs，表明在生理温度下致癌性Y220C变异体是锌离子结合功能的失活突变

Biochemistry

IF3

2026-09-15

PREAI

Jacob I. Stuckey; Valerie Vivat; Bradley M. Dickson; Jeremy W. Setser; Yong Li; Claudia M. Cremers; Jonathan E. Wilson; Daniele Peterle; John R. Engen; Thomas E. Wales; Rainer Wilcken; Erin B. Rohan; Gregg Chenail; James E. Audia; Robert J. Sims III

Perturbation of H2A.Z enrichment and variant composition in Arabidopsis thaliana is sufficient to alter H3K27me3 distribution and abundance in a locus-specific fashion 拟南芥中H2A.Z富集度和变异组成的扰动足以以位点特异性方式改变H3K27me3的分布和丰度

BMC Plant Biology

IF4.8

2026-09-09

OAAI

Jiaxin Long; Gustavo Agreda; Shelby Sliger; Jacob R. Fawley; Pete E. Pascuzzi; Bradley M. Dickson; Bryon Drown; Joe Ogas

DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states DNA低甲基化促进UHRF1和SUV39H1/H2依赖的H3K18ub与H3K9me3之间的串扰，以强化异染色质状态。

MOLECULAR CELL

IF16.6

2025-01-01

OAAI

Liu, Yanqing; Hrit, Joel A.; Chomiak, Alison A.; Stransky, Stephanie; Hoffman, Jordan R.; Tiedemann, Rochelle L.; Wiseman, Ashley K.; Kariapper, Leena S.; Dickson, Bradley M.; Worden, Evan J.; Fry, Christopher J.; Sidoli, Simone; Rothbart, Scott B.

UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation

NUCLEIC ACIDS RESEARCH

IF13.1

2024-11-28

OAAI

Tiedemann, Rochelle L.; Hrit, Joel; Du, Qian; Wiseman, Ashley K.; Eden, Hope E.; Dickson, Bradley M.; Kong, Xiangqian; Chomiak, Alison A.; Vaughan, Robert M.; Tibben, Bailey M.; Hebert, Jakob M.; David, Yael; Zhou, Wanding; Baylin, Stephen B.; Jones, Peter A.; Clark, Susan J.; Rothbart, Scott B.

Molecular dynamics simulations provide insights into ULK-101 potency and selectivity toward autophagic kinases ULK1/2 分子动力学模拟为ULK-101对自噬激酶ULK1/2的效力与选择性提供了见解。

biomolecular structure dynamics

IF0

2024-11-13

OAAI

Robert M. Vaughan; Bradley M. Dickson; Katie R. Martin; Jeffrey P. MacKeigan

The discovery of imidazo[4,5-c]pyridine-2-ones as selective inhibitors of DNA-dependent protein kinase and effective radiosensitisers

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Hay, M.; Hong, C.; Liew, L.; Dickson, B.; Wong, W.; O'Brien-Gortner, S.; Airey, R.; Wilson, W.; Jamieson, S.

Ketolysis drives CD8+T cell effector function through effects on histone acetylation 酮分解通过对组蛋白乙酰化的影响驱动CD8 T细胞效应子功能

IMMUNITY

IF26.3

2023-09-01

OAAI

Luda, Katarzyna M.; Longo, Joseph; Kitchen-Goosen, Susan M.; Duimstra, Lauren R.; Ma, Eric H.; Watson, McLane J.; Oswald, Brandon M.; Fu, Zhen; Madaj, Zachary; Kupai, Ariana; Dickson, Bradley M.; DeCamp, Lisa M.; Dahabieh, Michael S.; Compton, Shelby E.; Teis, Robert; Kaymak, Irem; Lau, Kin H.; Kelly, Daniel P.; Puchalska, Patrycja; Williams, Kelsey S.; Krawczyk, Connie M.; Levesque, Dominique; Boisvert, Francois-Michel; Sheldon, Ryan D.; Rothbart, Scott B.; Crawford, Peter A.; Jones, Russell G.

Streamlined quantitative analysis of histone modification abundance at nucleosome-scale resolution with siQ-ChIP version 2.0

SCIENTIFIC REPORTS

IF3.9

2023-05-09

OAAI

Dickson, Bradley M.; Kupai, Ariana; Vaughan, Robert M.; Rothbart, Scott B.

DNA strand asymmetry generated by CpG hemimethylation has opposing effects on CTCF binding

NUCLEIC ACIDS RESEARCH

IF13.1

2023-04-24

OAAI

Thomas, Stacey L.; Xu, Ting-Hai; Carpenter, Brittany L.; Pierce, Steven E.; Dickson, Bradley M.; Liu, Minmin; Liang, Gangning; Jones, Peter A.

Global lysine methylome profiling using systematically characterized affinity reagents

SCIENTIFIC REPORTS

IF3.9

2023-01-07

OAAI

Berryhill, Christine A.; Hanquier, Jocelyne N.; Doud, Emma H.; Cordeiro-Spinetti, Eric; Dickson, Bradley M.; Rothbart, Scott B.; Mosley, Amber L.; Cornett, Evan M.

A physical basis for quantitative ChIP-sequencing

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-11-01

OAAI

Dickson, Bradley M.; Tiedemann, Rochelle L.; Chomiak, Alison A.; Cornett, Evan M.; Vaughan, Robert M.; Rothbart, Scott B.

The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells

EPIGENETICS & CHROMATIN

IF3.5

2020-10-23

OAAI

Vaughan, Robert M.; Kupai, Ariana; Foley, Caroline A.; Sagum, Cari A.; Tibben, Bailey M.; Eden, Hope E.; Tiedemann, Rochelle L.; Berryhill, Christine A.; Patel, Varun; Shaw, Kevin M.; Krajewski, Krzysztof; Strahl, Brian D.; Bedford, Mark T.; Frye, Stephen V.; Dickson, Bradley M.; Rothbart, Scott B.

How fluxional reactants limit the accuracy/efficiency of infrequent metadynamics 流体反应物如何限制不常见的元动力学的准确性/效率

JOURNAL OF CHEMICAL PHYSICS

IF3.1

2020-08-07

OAAI

Khan, Salman A.; Dickson, Bradley M.; Peters, Baron

High-resolution Epigenome Mapping Reveals Distinct and Divergent Roles for UHRF1 in the Maintenance of DNA Methylation

FASEB JOURNAL

IF4.2

2020-04-18

OAAI

Tiedemann, Rochelle; Du, Qian; Dickson, Bradley; Kong, Xiangqian; Chomiak, Alison; Zhou, Wanding; Johnson, Benjamin; Baylin, Stephen; Jones, Peter; Clark, Susan; Rothbart, Scott

The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-10-01

OAAI

Vaughan, Robert M.; Rothbart, Scott B.; Dickson, Bradley M.

A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 (vol 12, pg 180, 2016)

NATURE CHEMICAL BIOLOGY

IF13.7

2019-03-06

OAAI

Stuckey, Jacob I.; Dickson, Bradley M.; Cheng, Nancy; Liu, Yanli; Norris, Jacqueline L.; Cholensky, Stephanie H.; Tempel, Wolfram; Qin, Su; Huber, Katherine G.; Sagum, Cari; Black, Karynne; Li, Fengling; Huang, Xi-Ping; Roth, Bryan L.; Baughman, Brandi M.; Senisterra, Guillermo; Pattenden, Samantha G.; Vedadi, Masoud; Brown, Peter J.; TBedford, Mark; Min, Jinrong; Arrowsmith, Cheryl H.; James, Lindsey I.; Frye, Stephen V.

Erroneous Rates and False Statistical Confirmations from Infrequent Metadynamics and Other Equivalent Violations of the Hyperdynamics Paradigm 不常见的元动力学和其他等效违反超动力学范式的错误比率和错误的统计确认

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2018-11-23

PREAI

Dickson, Bradley M.

A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

SCIENCE ADVANCES

IF12.5

2018-11-02

OAAI

Cornett, Evan M.; Dickson, Bradley M.; Krajewski, Krzysztof; Spellmon, Nicholas; Umstead, Andrew; Vaughan, Robert M.; Shaw, Kevin M.; Versluis, Philip P.; Cowles, Martis W.; Brunzelle, Joseph; Yang, Zhe; Vega, Irving E.; Sun, Zu-Wen; Rothbart, Scott B.

Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies

MOLECULAR CELL

IF16.6

2018-10-01

OAAI

Shah, Rohan N.; Grzybowski, Adrian T.; Cornett, Evan M.; Johnstone, Andrea L.; Dickson, Bradley M.; Boone, Brandon A.; Cheek, Marcus A.; Cowles, Martis W.; Maryanski, Danielle; Meiners, Matthew J.; Tiedemann, Rochelle L.; Vaughan, Robert M.; Arora, Neha; Sun, Zu-Wen; Rothbart, Scott B.; Keogh, Michael-Christopher; Ruthenburg, Alexander J.

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-08-13

OAAI

Vaughan, Robert M.; Dickson, Bradley M.; Whelihan, Matthew F.; Johnstone, Andrea L.; Cornett, Evan M.; Cheek, Marcus A.; Ausherman, Christine A.; Cowles, Martis W.; Sun, Zu-Wen; Rothbart, Scott B.

研究方向