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Xiang-Li Ning

sichuan university

8H指数
15论文数
168被引数
收录论文 9
发表时间
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Structural Optimization of Benzyl-5-methyl-1H-Imidazole Derivatives as Human Glutaminyl Cyclase Inhibitors苯基-5-甲基-1H-咪唑衍生物作为人谷氨酰胺环化酶抑制剂的构效关系优化
errACS Medicinal Chemistry Letters
IF4
err2026-02-01
err0
PREAI
errChen, Yu-Ting; Meng, Fan-Bo; Zhuang, Yu-Qing; Chen, Zi-Yang; Wang, Yao-Geng; Ning, Xiang-Li; Liu, Wen-Yi; Li, Rong; Wang, Hua-Li; Li, Guo-Bo
err分享
err收藏
Deciphering Glutaminyl Cyclase Catalytic Pathways Enables Recognition of Anchor Pharmacophores for Inhibitor Discovery解析谷氨酰胺酰环化酶催化通路有助于识别抑制剂发现中的锚定药效基团
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-05-14
err0
PREAI
errWu, Jing-Wei; Ning, Xiang-Li; Tang, Biao-Dan; Chen, Yi-Ting; Yang, Zeng-Bao; Meng, Fan-Bo; Zhou, Cong; Yu, Jun-Lin; Li, Rong; Li, Zhe
err分享
err收藏
Knowledge-guided diffusion model for 3D ligand-pharmacophore mapping知识引导的3D配体-药效基映射扩散模型
errNATURE COMMUNICATIONS
IF15.7
err2025-03-06
err1
errOAAI
errYu, Jun-Lin; Zhou, Cong; Ning, Xiang-Li; Mou, Jun; Meng, Fan-Bo; Wu, Jing-Wei; Chen, Yi-Ting; Tang, Biao-Dan
err分享
err收藏
Discovery, synthesis and biological evaluation of novel isoquinoline derivatives as potent indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase dual inhibitors新型异喹啉衍生物作为吲哚胺2，3-双加氧酶1和色氨酸2，3-双加氧酶双重抑制剂的发现，合成和生物学评价
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-12-01
err0
PREAI
errLin, Zhiqian; Ning, Xiangli; Lai, Ruizhi; Hai, Li; Nie, Ruifang; Guo, Li; Li, Guobo; Yang, Zhongzhen; Wu, Yong
err分享
err收藏
X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-05-31
err0
PREAI
errMou, Jun; Ning, Xiang-Li; Wang, Xin-Yue; Hou, Shu-Yan; Meng, Fan-Bo; Zhou, Cong; Wu, Jing-Wei; Li, Chunyan; Jia, Tao; Wu, Xiaoai; Wu, Yong; Chen, Yongping; Li, Guo-Bo
err分享
err收藏
4,6-Disubstituted-1H-Indazole-4-Amine derivatives with immune-chemotherapy effect and in vivo antitumor activity
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-11-01
err3
PREAI
errHuo, Cui; Luo, Zongyuan; Ning, Xiangli; Kang, Xin; Yan, Qin; Guo, Yuying; Li, Guobo; Wang, Zhouyu; Li, Yuzhi; Qian, Shan
err分享
err收藏
AncPhore: A versatile tool for anchor pharmacophore steered drug discovery with applications in discovery of new inhibitors targeting metallo-β-lactamases and indoleamine/tryptophan 2,3-dioxygenasesAncPhore: 锚定药效团导向药物发现的通用工具，可用于发现靶向金属-β-内酰胺酶和吲哚胺/色氨酸2，3-双加氧酶的新抑制剂
errACTA PHARMACEUTICA SINICA B
IF14.6
err2021-07-01
err26
errOAAI
errDai, Qingqing; Yan, Yuhang; Ning, Xiangli; Li, Gen; Yu, Junlin; Deng, Ji; Yang, Lingling; Li, Guo-Bo
err分享
err收藏
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's DiseaseX射线结构指导下发现了一种有效的，口服生物可利用的双重人类吲哚胺/色氨酸2，3-双加氧酶 (hIDO/hTDO) 抑制剂，该抑制剂在帕金森氏病的小鼠模型中显示出活性
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-06-10
err14
PREAI
errNing, Xiang-Li; Li, Yu-Zhi; Huo, Cui; Deng, Ji; Gao, Cheng; Zhu, Kai-Rong; Wang, Miao; Wu, Yu-Xiang; Yu, Jun-Lin; Ren, Ya-Li; Luo, Zong-Yuan; Li, Gen; Chen, Yang; Wang, Si-Yao; Peng, Cheng; Yang, Ling-Ling; Wang, Zhou-Yu; Wu, Yong; Qian, Shan; Li, Guo-Bo
err分享
err收藏
Synthesis of a novel tri-substituted triazine monomer used for UV curable intumescent flame-retardant coating
errJOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
IF3.1
err2018-03-01
err2
PREAI
errNing, Xiangli; Liang, Hongbo; Bu, Jiang; Xiong, Lei; Huang, Shengmei; Xu, Haitao
err分享
err收藏

研究方向

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合作学者
合作期刊
彭成 封面图
彭成 (Cheng Peng)
H 指数: 89 · 论文数: 1.8K
秦
秦岩 (Yan Qin)
H 指数: 50 · 论文数: 427
J
Jun Mou
H 指数: 46 · 论文数: 210
L
Lingling Yang
H 指数: 43 · 论文数: 252
郭丽 封面图
郭丽 (Li Guo)
H 指数: 43 · 论文数: 367
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