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郭丽 封面图

郭丽 (Li Guo)

chengdu university of traditional chinese medicine

43H指数
367论文数
1.1W被引数
收录论文 149
发表时间
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Strategies for Targeting Mitochondria in the Treatment of Breast Cancer靶向线粒体治疗乳腺癌的策略
errACS Pharmacology & Translational Science
IF3.7
err2026-07-02
err0
errOAAI
errKexin Wang; Xianyi Zheng; Yating Li; Chunyan Li; Xiaoyong Zhang; Qichuan Deng; Hao Yang; Xiaocui Shuai; Jinqi Li; Li Guo; Jianyou Shi; Lan Bai
err分享
err收藏
Structural-guided identification of two modulators of β−1,3-glucan synthase FKS1结构指导的两种β−1,3-葡聚糖合酶FKS1调节剂的鉴定
errNature Communications
IF15.7
err2025-12-07
err0
errOAAI
errJialu Li; Jian Li; Angqi Zhu; Xinli Dai; Juxiu Liu; Huayi Liu; Zhili Xia; Yuefan Dong; Wenyu Qian; Lunzhi Dai; Li Guo; Chuangye Yan; Dong Deng; Yunzi Luo; Xiang Wang
err分享
err收藏
Structural Characterization and Protective Effects of CPAP-1, an Arabinogalactan from Curcuma phaeocaulis Val., Against H2O2-Induced Oxidative Damage in HUVECsCPAP-1的结构表征及其对H₂O₂诱导的人脐静脉内皮细胞（HUVECs）氧化损伤的保护作用（CPAP-1为凹唇姜Curcuma phaeocaulis Val.来源的一种阿拉伯半乳聚糖）
errMolecules
IF4.6
err2025-11-09
err0
errOAAI
errYuhao Long; Sirui Yi; Huizhi Zhou; Fangrou Chen; Yiping Guo; Li Guo
err分享
err收藏
Rapid detection of aflatoxins B1, B2, G1, G2, and total aflatoxins in citri reticulatae pericarpium and coicis seed based on nitrogen-doped carbon quantum dots基于氮掺杂碳量子点的柑橘皮和薏苡仁中黄曲霉毒素B1、B2、G1、G2及总黄曲霉毒素的快速检测
errJournal of Food Composition and Analysis
IF4.6
err2025-10-24
err0
PREAI
errXin Tan; Sirui Yi; Xiaohang Wei; Tingting Li; Guangli Ai; Yiping Guo; Li Guo
err分享
err收藏
Thematic analysis of narrated reasons for suicidal ideation among Chinese adolescents in psychological counseling中国青少年在心理咨询中叙述自杀意念原因的主题分析
errFrontiers in Psychiatry
IF3.2
err2025-09-30
err0
errOAAI
errLi Guo†; Nan Zhang†; Shuzhen Chen
err分享
err收藏
Comparison of the effect of acupoint injection and tramadol for the treatment of catheter-related bladder discomfort: A randomized controlled trial比较穴位注射与曲马多治疗导管相关性膀胱不适的效果：一项随机对照试验
errMEDICINE
IF1.4
err2025-09-12
err0
errOAAI
errGuo, Li; Li, Ping; Li, Shuying; Song, Jianying; Wang, Qiaoli; Tian, Wanli
err分享
err收藏
Dual-protein embedding-based graph model with dynamic attention for interaction prediction基于双蛋白嵌入的动态注意力交互预测图模型
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2025-09-01
err0
errOAAI
errPang, Shunpeng; Jiang, Mingjian; Zhang, Shugang; Wang, Shuang; Li, Zhen; Sun, Jing; Zhang, Yuanyuan; Guo, Li
err分享
err收藏
Covalent halogenation of polyethylene glycol-based flame-retardant phase change materials for safe energy storage基于聚乙二醇的阻燃相变材料的共价卤化改性用于安全储能
erriScience
IF4.1
err2025-07-25
err0
errOAAI
errLong Geng; Guangyuan Liang; Xiao Zhang; Yitong Cao; Guo Li; Yixuan Lin; Zafar Said; Changhui Liu
err分享
err收藏
Acidic Ionic Liquids-Catalyzed Dehydration Cross-Coupling Reaction of Allyl Alcohols with Phosphine Oxides酸性离子液体催化的烯丙醇与磷氧化物脱水交叉偶联反应
errAsian Journal of Organic Chemistry
IF2.7
err2025-07-01
err0
PREAI
errLi Guo; Yingning Qin; Feiyang Lan; Chaofan Han; Xinye Zhang; Xirui Ding; Prof.Dr. Feng Han
err分享
err收藏
Metal-Free Catalytic Access to Indanes via Intermolecular Cyclization from Internal Olefins/Ethers and Mechanism Study无金属催化通过分子间环化反应从内烯烃/醚合成二氢萘及其机理研究
errEuropean Journal of Organic Chemistry
IF2.7
err2025-06-30
err0
PREAI
errHaotian Lv; Yinuo Zhu; Feng Han; Li Guo; Nan Lu; Yuanhong Zhang; Chengxia Miao
err分享
err收藏
Effects of blood sample mishandling on anti-HCV IgG antibodies血样处理不当对anti-HCV IgG抗体的影响
errLANCET REGIONAL HEALTH-AMERICAS
IF7.6
err2025-06-01
err0
PREAI
errYang, Lihua; Wang, Yongzhi; Zhao, Yibo; Zhang, Fangyu; Guo, Li; Yan, Xiaogang; Zhao, Jinghui
err分享
err收藏
BRD4 regulates PAI-1 expression in tumor-associated macrophages to drive chemoresistance in colorectal cancerBRD4通过调节肿瘤相关巨噬细胞中PAI-1的表达来驱动结直肠癌的化疗耐药性。
errONCOGENE
IF7.3
err2025-05-28
err0
PREAI
errPan, Dun; Hu, Jinfeng; Li, Guo; Gao, Xuming; Wang, Jie; Jiang, Leisi; Lin, Hong; Chen, Yulin; Chen, Yanheng; Zheng, Yiran; Lin, Junjin; Zheng, Min; Chen, Hui; Chen, Lin-Feng; Hu, Xiangming
err分享
err收藏
Visible-Light-Induced C-H Alkylation of 1,2,4-Triazine-3,5(2H,4H)-diones via Infrequent 1,2-Hydrogen-Atom Transfer可见光诱导的1,2,4-三嗪-3,5(2H,4H)-二酮的C-H烷基化反应：通过罕见的1,2-氢原子转移实现
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2025-05-19
err0
PREAI
errWang, Mi; Wang, Yangyang; Wang, Jie; Zhu, Yafei; Zhang, Penghua; Zhang, Cuimei; Chen, Jian; Guo, Li; Lv, Guanghui; Wu, Yong
err分享
err收藏
Study of Folate-Modified Carboxymethyl Chitosan-Sinomenine-Curcumin Nanopolymer for Targeted Treatment of Rheumatoid Arthritis叶酸修饰的羧甲基壳聚糖-秦艽碱-姜黄素纳米聚合物靶向治疗类风湿关节炎的研究
errBIOMACROMOLECULES
IF5.4
err2025-05-05
err0
PREAI
errTang, Jiamei; Li, Sihui; Wang, Yulu; Yuan, Minghao; Wan, Yan; Liang, Xue; Guo, Li; Guo, Yiping
err分享
err收藏
2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as D3R-Selective Ligands for 3D-QSAR, Docking and Molecular Dynamics Simulation Studies2-苯基环丙基甲基胺（PCPMA）衍生物作为D3R-选择性配体，用于3D-QSAR、对接和分子动力学模拟研究
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-04-10
err0
errOAAI
errGuo, Li; Gao, Yuepeng; Zhang, Sujuan; Zhao, Lingmi; Zhao, Runxin; Sun, Pinghua; Pan, Xinhui; Zhang, Wei
err分享
err收藏
Identification of neutralizing nanobodies protecting against poxvirus infection鉴定能够抵抗痘病毒感染的中和纳米抗体
errCELL DISCOVERY
IF12.5
err2025-03-25
err0
errOAAI
errYang, Xuehua; Guo, Li; Duan, Huarui; Fan, Miao; Xu, Fengwen; Chi, Xiaojing; Pan, Shengnan; Liu, Xiuying; Zhang, Xinhui; Gao, Peixiang; Zhang, Fangyuan; Wang, Xinyi; Guo, Fei; Ge, Jiwan; Ren, Lili; Yang, Wei
err分享
err收藏
Blue-Light-Induced Stereoselective Synthesis of α-Alkylated Amino Acid Derivatives蓝光诱导的α-烷基化氨基酸衍生物立体选择性合成
errEUROPEAN JOURNAL OF ORGANIC CHEMISTRY
IF2.7
err2025-03-21
err0
PREAI
errFan, Hongying; Ye, Meiling; Zhang, Xue; Hou, Jinyu; Jiao, Liulin; Chen, Jian; Guo, Li; Lian, Zhong
err分享
err收藏
An oxidation-reduction-triggered thiamine disulfide-based prodrug of 10-hydroxycamptothecin for selective tumor cell locking and therapeutic delivery
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err0
PREAI
errYang, Chunyan; Yu, Peiyun; Chen, Jinxia; Lu, Runxin; Hai, Li; Yang, Zhongzhen; Guo, Li; Wu, Yong
err分享
err收藏
First-in-human study on tolerability, pharmacokinetics and pharmacodynamics of single and multiple escalating doses of XKH001, a recombinant humanized monoclonal antibody against IL-25 in healthy Chinese volunteers
errEXPERT OPINION ON INVESTIGATIONAL DRUGS
IF4.1
err2025-01-20
err0
PREAI
errZhang, Hong; Zheng, Wenbo; Peng, Ran; Wu, Dandan; Hu, Yue; Sun, Tiantian; Gao, Lei; Liu, Yusi; Guo, Li; Ding, Yanhua; Liu, Li
err分享
err收藏
Visible-Light-Induced Glycosylation/Annulation of 2-Isocyanobiaryls and Glycosyl NHP Esters to Access Nonclassical Heteroaryl C-Glycosides可见光诱导的2-异氰基联苯基和糖基NHP酯的糖基化/成环，以获取非经典的杂芳基C-糖苷
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2025-01-13
err0
PREAI
errLv, Guanghui; Wang, Yangyang; Zhang, Penghua; Zhu, Yafei; Wang, Mi; Ma, Zhaohui; Zhang, Cuimei; Chen, Jian; Guo, Li; Wu, Yong
err分享
err收藏

研究方向

靶向药物及聚集型多肽药物的研究树枝状化合物在药物研究中的应用主要论著（2012～）树状聚合物萘普生前药合成羟基磷灰石结合Janus树枝状聚合物合成骨靶向药物递送双靶向递送系统骨癌药物递送Janus树枝状聚合物设计与合成亲脂化抗氧化剂双靶向Janus树枝状聚合物肽用于骨癌合成与初步生物学评价酶切NSAIDs前药设计自毁性树枝状支架合成炎症性疾病治疗分子对接QSAR分子动力学模拟Multicomplex-based pharmacophoreQSAR of aryl-sulfamides杂环化合物合成亚胺狄尔斯-阿尔德反应基于PepT1的寡肽前药合成与肠吸收评价甘草次酸修饰的泊洛沙姆188/壳聚糖纳米粒制备与表征细胞穿透性赖氨酸树枝状聚合物抗癌药物递送合成与生物评价没食子酸二聚体和四聚体抗氧化活性抗增殖活性RGD-Modified Lipid-Polymer Hybrid NanoparticlesTargeted Drug Delivery脑靶向前药设计盐酸西那卡塞相关物质合成Heck偶联反应synthesis of Rizatriptan甘草酸修饰聚乙二醇-聚（β-苄基-L-天冬氨酸）纳米粒肝脏靶向递送系统骨靶向非甾体抗炎药前药谷氨酸寡肽抗肝细胞癌药物联吡嗪衍生物合成Ulipristal acetate立体异构体合成表征胆汁分泌药物二羟基二丁醚立体异构体的合成与表征树状聚合物自组装胶束药物递送骨肉瘤细胞靶向吡咯烷螺氧吲哚合成类胆汁酸类似物合成靛红合成吡啶氯铬酸盐催化分子内环化反应Ru(III)介导的分子内邻位C(sp2)-H活化/氧化酰化一锅法合成靛蓝酮立体异构体合成光声成像造影剂Ligand-free C-C coupling reaction编辑：四川大学华西药学院
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