Jiunn H. Lin - Publications, H-index & Citations

Jiunn H. Lin

harvard university medical affiliates

60H指数

150论文数

1.2W被引数

收录论文 29

发表时间

Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-03-02

OAAI

Rynearson, Kevin D.; Ponnusamy, Moorthi; Prikhodko, Olga; Xie, Yuhuan; Zhang, Can; Nguyen, Phuong; Hug, Brenda; Sawa, Mariko; Becker, Ann; Spencer, Brian; Florio, Jazmin; Mante, Michael; Salehi, Bahar; Arias, Carlos; Galasko, Douglas; Head, Brian P.; Johnson, Graham; Lin, Jiunn H.; Duddy, Steven K.; Rissman, Robert A.; Mobley, William C.; Thinakaran, Gopal; Tanzi, Rudolph E.; Wagner, Steven L.

Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2017-07-01

OAAI

Wagner, Steven L.; Rynearson, Kevin D.; Duddy, Steven K.; Zhang, Can; Nguyen, Phuong D.; Becker, Ann; Vo, Uyen; Masliah, Deborah; Monte, Louise; Klee, Justin B.; Echmalian, Corinne M.; Xia, Weiming; Quinti, Luisa; Johnson, Graham; Lin, Jiunn H.; Kim, Doo Y.; Mobley, William C.; Rissman, Robert A.; Tanzi, Rudolph E.

Transporter-mediated drug interactions:: clinical implications and in vitro assessment 转运蛋白介导的药物相互作用: 临床意义和体外评估

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2007-02-01

PREAI

Lin, Jiunn H.

Complicating factors in safety testing of drug metabolites: Kinetic differences between generated and preformed metabolites

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2006-12-01

PREAI

Prueksaritanont, Thomayant; Lin, Jiunn H.; Baillie, Thomas A.

CYP induction-mediated drug interactions:: in vitro assessment and clinical implications

PHARMACEUTICAL RESEARCH

IF4.3

2006-05-26

238

PREAI

Lin, Jiunn H.

Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: Effects of gemfibrozil 辛伐他汀及其羟基酸在狗体内的相互转化药代动力学: 吉非贝齐的影响

PHARMACEUTICAL RESEARCH

IF4.3

2005-07-22

PREAI

Prueksaritanont, T; Qiu, Y; Mu, L; Michel, K; Brunner, J; Richards, KM; Lin, JH

Using real-time quantitative TaqMan RT-PCR to evaluate the role of dexamethasone in gene regulation of rat P-glycoproteins mdr1a/1b and cytochrome p450 3A1/2

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2004-10-01

PREAI

Mei, Q; Richards, K; Strong-Basalyga, K; Fauty, SE; Taylor, A; Yamazaki, M; Prueksaritanont, T; Lin, JH; Hochman, J

Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin

PHARMACEUTICAL RESEARCH

IF4.3

2004-09-01

114

PREAI

Hochman, JH; Pudvah, N; Qiu, J; Yamazaki, M; Tang, C; Lin, JH; Prueksaritanont, T

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2004-07-26

321

OAAI

Hazuda, DJ; Anthony, NJ; Gomez, RP; Jolly, SM; Wai, JS; Zhuang, LH; Fisher, TE; Embrey, M; Guare, JP; Egbertson, MS; Vacca, JP; Huff, JR; Felock, PJ; Witmer, MV; Stillmock, KA; Danovich, R; Grobler, J; Miller, MD; Espeseth, AS; Jin, LX; Chen, IW; Lin, JH; Kassahun, K; Ellis, JD; Wong, BK; Xu, W; Pearson, PG; Schleif, WA; Cortese, R; Emini, E; Summa, V; Holloway, MK; Young, SD

Clinical relevance of P-glycoprotein in drug therapy

DRUG METABOLISM REVIEWS

IF3.8

2003-08-12

171

PREAI

Lin, JH; Yamazaki, M

Pharmacokinetics and interactions of a novel antagonist of chemokine receptor 5 (CCR5) with ritonavir in rats and monkeys: Role of CYP3A and P-glycoprotein

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2003-03-01

PREAI

Kumar, S; Kwei, GY; Poon, GK; Iliff, SA; Wang, YF; Chen, Q; Franklin, RB; Didolkar, V; Wang, RW; Yamazaki, M; Chiu, SHL; Lin, JH; Pearson, PG; Baillie, TA

Metabolic activation of a pyrazinone-containing thrombin inhibitor. Evidence for novel biotransformation involving pyrazinone ring oxidation, rearrangement, and covalent binding to proteins

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2003-01-24

PREAI

Singh, R; Elipe, MVS; Pearson, PG; Arison, BH; Wong, BK; White, R; Yu, X; Burgey, CS; Lin, JH; Baillie, TA

Drug-drug interaction mediated by inhibition and induction of P-glycoprotein

ADVANCED DRUG DELIVERY REVIEWS

IF17.6

2003-01-01

292

PREAI

Lin, JH

Design and synthesis of a pro-drug of vinblastine targeted at treatment of prostate cancer with enhanced efficacy and reduced systemic toxicity

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2002-09-05

PREAI

Brady, SF; Pawluczyk, JM; Lumma, PK; Feng, DM; Wai, JM; Jones, R; DeFeo-Jones, D; Wong, BK; Miller-Stein, C; Lin, JH; Oliff, A; Freidinger, RM; Garsky, VM

Mechanistic studies on metabolic interactions between gemfibrozil and statins

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2002-06-01

235

PREAI

Prueksaritanont, T; Zhao, JJ; Ma, B; Roadcap, BA; Tang, CY; Qiu, Y; Liu, LD; Lin, JH; Pearson, PG; Baillie, TA

Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors:: an in vitro investigation with human liver preparations

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2001-12-24

OAAI

Prueksaritanont, T; Ma, B; Tang, CY; Meng, Y; Assang, C; Lu, P; Reider, PJ; Lin, JH; Baillie, TA

P450 interaction with farnesyl-protein transferase inhibitors - Metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes

BIOCHEMICAL PHARMACOLOGY

IF5.6

2001-09-01

PREAI

Chiba, M; Tang, CY; Neway, WE; Williams, TM; Desolms, SJ; Dinsmore, CJ; Wai, JS; Lin, JH

Screening of drug candidates for their drug-drug interaction potential

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2001-08-01

PREAI

Rodrigues, AD; Lin, JH

Interindividual variability in inhibition and induction of cytochrome P450 enzymes

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY

IF13.1

2001-04-01

231

PREAI

Lin, JH; Lu, AYH

A peptide-doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo

NATURE MEDICINE

IF50

2000-11-01

179

PREAI

DeFeo-Jones, D; Garsky, VM; Wong, BK; Feng, DM; Bolyar, T; Haskell, K; Kiefer, DM; Leander, K; McAvoy, E; Lumma, P; Wai, J; Senderak, ET; Motzel, SL; Keenan, K; Van Zwieten, M; Lin, JH; Freidinger, R; Huff, J; Oliff, A; Jones, RE

研究方向