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D

Denise P. Muñoz

University of California San Francisco
H指数:13
被引数:3,747

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Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype

超增强子分析揭示ThPOK/ZBTB7B，一种CD4+细胞谱系决定因子，作为主调控因子限制乳腺癌细胞呈现管腔非迁移表型

Cellular and Molecular Life Sciences
IF6.2
2025-11-130
OAAI
Camila D. Arcuschin; Kamin Kahrizi; Rosalyn W. Sayaman; Carolina DiBenedetto; Pedro J. Salaberry; Roxana Pirker; Yizhuo Shen; Ons Zakraoui; Cecilia Schwarzer; Alessandro Scapozza; Joseph A. Caruso; Paola Betancur; Julie D. Saba; Jean-Philippe Coppé; Mary-Helen Barcellos-Hoff; Dietmar Kappes; Laura van ‘t Veer; Ignacio E. Schor; Denise P. Muñoz
Inflammation-driven Resistance to MAPK inhibition in Pediatric Gliomas: Mechanisms and Therapeutic Strategies

炎症驱动的MAPK抑制耐药性在儿童胶质瘤中的机制与治疗策略

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Panovska, Dena; Xing, Yao Lulu; Nasajpour, Emon; Dobler, Rosalie; Zakaraoui, Ons; Baroncini, Luca; Caruso, Joseph; Priker, Roxana; Munoz, Denise; Banik, Ishani; Nguyen, David; Hwang, Yeonjoo; Lin, Hui; Wei, Ruolun; Dhami, Tejas; Ngok, Erica; Lim, Michael; Ryan, Katherine; Stucklin, Ana Guerreiro; Coppe, Jean-Philippe; Petritsch, Claudia Katharina
Combinatorial targeting of avapritinib-driven MAPK activation in pediatric high-grade glioma

阿伐普利尼布诱导的MAPK激活在儿童高级别胶质瘤中的组合靶向治疗

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Schwark, Kallen; Miclea, Madeline; Patel, Tirth; Kong, Seongbae; Stanczak, Alina; Lau, Benison; Cartaxo, Rodrigo; Messinger, Dana; Doherty, Robert; Ji, Sunjong; Wadden, Jack; Clausen, Madison; Momen, Fareen; Adam, Tiffany; Wink, Kelsey; Hutchinson, Aria; Niculcea, Michael; Serhan, Habib; Merrill, Nathan; Edmonds, Amy; Mayr, Lisa; Neyazi, Sina; Munoz, Denise; Nuechterlein, Nicholas; Fernandez, Ester Calvo; Califano, Andrea; Pavisic, Jovana; Garton, Hugh; Rao, Rama; Upadhyaya, Santhosh; Skrypek, Mary; Bendel, Anne; Lobbous, Mina; Klawinski, Darren; Merajver, Sofia; Koptyra, Mateusz; Resnick, Adam; Nazarian, Javad; Venneti, Sriram; Waszak, Sebastian; Chavez, Lukas; Beck, Alexander; Gojo, Johannes; Filbin, Mariella; Coppe, Jean-Philippe; Koschmann, Carl
Dynamic kinome reprogramming drives resistance to treatments in BRAFV600E pediatric gliomas, revealing actionable therapeutic vulnerabilities

动态激酶组重编程驱动BRAFV600E儿童胶质瘤对治疗的耐药性，揭示了可操作的 therapeutic vulnerabilities。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Panovska, Dena; Dobler, Rosalie; Zakraoui, Ons; Xing, Lulu; Baroncini, Luca; Caruso, Joseph; Pirker, Roxana; Munoz, Denise; Nasajpour, Emon; Banik, Ishani; Nguyen, David; Hwang, Yeonjoo; Lin, Hui; Stucklin, Ana Guerreiro; Petritsch, Claudia; Coppe, Jean-Philippe
Targeting CDK1/2-driven mechanisms of resistance to BRAF and EGFR inhibition in BRAF(V600E) colorectal cancer restores therapeutic response
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Coppe, Jean-Philippe; Munoz, Denise P.; Atreya, Chloe E.; Hwang, Yeonjoo; Bouhaddou, Mehdi; Heinrich, Louise E.; Naser, Mohammad; Zakraoui, Ons; Pirker, Roxana; Guha, Rupa; Moelders, Christina; Scapozza, Alessandro; Schwarzer, Cecilia; Phillips, Layla; Wang, Changjun; van 't Veer, Laura; Steri, Veronica; VandenBerg, Scott R.
The therapeutically actionable long non-coding RNA 'T-RECS' is essential to cancer cells' survival in NRAS/MAPK-driven melanoma
MOLECULAR CANCER
IF33.9
2024-02-222
OAAI
Feichtenschlager, Valentin; Chen, Linan; Zheng, Yixuan James; Ho, Wilson; Sanlorenzo, Martina; Vujic, Igor; Fewings, Eleanor; Lee, Albert; Chen, Christopher; Callanan, Ciara; Lin, Kevin; Qu, Tiange; Hohlova, Dasha; Vujic, Marin; Hwang, Yeonjoo; Lai, Kevin; Chen, Stephanie; Nguyen, Thuan; Munoz, Denise P.; Kohwi, Yoshinori; Posch, Christian; Daud, Adil; Rappersberger, Klemens; Kohwi-Shigematsu, Terumi; Coppe, Jean-Philippe; Ortiz-Urda, Susana
Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-11-1512
OAAI
Chong, Stephen Jun Fei; Zhu, Fen; Dashevsky, Olga; Mizuno, Rin; Lai, Jolin X. H.; Hackett, Liam; Ryan, Christine E.; Collins, Mary C.; Iorgulescu, J. Bryan; Guieze, Romain; Penailillo, Johany; Carrasco, Ruben; Hwang, Yeonjoo C.; Munoz, Denise P.; Bouhaddou, Mehdi; Lim, Yaw Chyn; Wu, Catherine J.; Allan, John N.; Furman, Richard R.; Goh, Boon Cher; Pervaiz, Shazib; Coppe, Jean-Philippe; Mitsiades, Constantine S.; Davids, Matthew S.
A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors
NATURE CANCER
IF28.5
2023-02-0918
OAAI
Ruiz-Saenz, Ana; Atreya, Chloe E.; Wang, Changjun; Pan, Bo; Dreyer, Courtney A.; Brunen, Diede; Prahallad, Anirudh; Munoz, Denise P.; Ramms, Dana J.; Burghi, Valeria; Spassov, Danislav S.; Fewings, Eleanor; Hwang, Yeonjoo C.; Cowdrey, Cynthia; Moelders, Christina; Schwarzer, Cecilia; Wolf, Denise M.; Hann, Byron; VandenBerg, Scott R.; Shokat, Kevan; Moasser, Mark M.; Bernards, Rene; Gutkind, J. Silvio; van 't Veer, Laura J.; Coppe, Jean-Philippe
A protein interaction landscape of breast cancer
Science
IF45.8
2021-01-010
OA
Minkyu Kim; Jisoo Park; Mehdi Bouhaddou; Kyumin Kim; Ajda Rojc; Maya Modak; Margaret Soucheray; Michael McGregor; Patrick C. O’Leary; Denise M. Wolf; Erica J. Stevenson; Tzeh Keong Foo; Dominique C. Mitchell; Kari A. Herrington; Denise P. Muñoz; Beril Tutuncuoglu; Kuei‐Ho Chen; Fan Zheng; Jason F. Kreisberg; Morgan E. Diolaiti; John Dozier Gordan; Jean‐Philippe Coppé; Danielle L. Swaney; Bing Xia; Laura van ‘t Veer; Alan Ashworth; Trey E. Ideker; Nevan J. Krogan

研究方向

暂未获取到该数据
J
Jean‐Philippe Coppé
H 指数:24论文数:78被引数:1.8万
Y
Yeonjoo Hwang
H 指数:7论文数:40被引数:424
F
Françis Rodier
H 指数:41论文数:157被引数:1.5万
J
Judith Campisi
H 指数:129论文数:519被引数:9.7万
J
Jean-Philippe Coppé
H 指数:8论文数:21被引数:1,568
M
Mehdi Bouhaddou
H 指数:29论文数:102被引数:1.0万
A
Adam Freund
H 指数:17论文数:53被引数:9,852
J
Joseph A. Caruso
H 指数:66论文数:520被引数:1.7万
E
Eric Campeau
H 指数:20论文数:86被引数:4,873
L
Laura van ‘t Veer
H 指数:71论文数:513被引数:4.8万