Mehdi Bouhaddou - Publications, H-index & Citations

Mehdi Bouhaddou

University of California System

29H指数

101论文数

1.0W被引数

收录论文 30

发表时间

Pharmacological reprogramming of plitidepsin as a SARS-CoV-2 inhibitor plitidepsin的药理重编程作为SARS-CoV-2抑制剂

Molecular Aspects of Medicine

IF10.3

2025-11-10

PREAI

Jose Jimeno; Jose Felipe Varona; Jose A. Lopez-Martin; Nuria Izquierdo-Useros; Elisa Molina Molina; Pablo Guisado-Vasco; Martin Sachse; Cristina Risco; Alejandro Losada; Salvador Fudio; Erik Luepke; Antonio Nieto; Javier Gomez; Pablo Aviles; Carmen Cuevas; Mehdi Bouhaddou; Isabel Sola; Nevan J. Krogan; Luis Enjuanes; Jose M. Fernandez-Sousa; Adolfo GarcÍa-Sastre; Kris White

Old World alphaviruses use distinct mechanisms to infect brain microvascular endothelial cells for neuroinvasion 旧世界阿尔法病毒通过不同的机制感染脑微血管内皮细胞以实现神经侵袭。

Cell Reports

IF6.9

2025-09-22

OAAI

Pablo A. Alvarez; Ashley Tang; Declan M. Winters; Prashant Kaushal; Angelica Medina; Maria Villalba Nieto; Karolina E. Kaczor-Urbanowicz; Faith St. Amant; Bryan Ramirez Reyes; Robyn M. Kaake; Oliver I. Fregoso; April D. Pyle; Mehdi Bouhaddou; Hengli Tang; Melody M.H. Li

HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137 HIV Vpr激活一种核仁特异性ATR通路以降解核仁应激传感器CCDC137

NUCLEIC ACIDS RESEARCH

IF13.1

2025-06-24

OAAI

Nisson, Karly A.; Patel, Rishi S.; Delgado, Yennifer; Bouhaddou, Mehdi; Etienne, Lucie; Fregoso, Oliver, I

Malaria exposure remodels the plasma proteome of Ghanaian children

BMC INFECTIOUS DISEASES

IF3

2025-02-03

OAAI

Mohammed, Aisha M.; Olwal, Charles Ochieng'; Fossati, Andrea; Nyakoe, Nancy K.; Fabius, Jacqueline M.; Gordon, Martin; Polacco, Benjamin J.; Swaney, Danielle L.; Awandare, Gordon A.; Krogan, Nevan J.; Bouhaddou, Mehdi; Bediako, Yaw

SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation

PLOS PATHOGENS

IF4.9

2024-11-21

OAAI

Syed, Abdullah M.; Ciling, Alison; Chen, Irene P.; Carlson, Christopher R.; Adly, Armin N.; Martin, Hannah S.; Taha, Taha Y.; Khalid, Mir M.; Price, Nathan; Bouhaddou, Mehdi; Ummadi, Manisha R.; Moen, Jack M.; Krogan, Nevan J.; Morgan, David O.; Ott, Melanie; Doudna, Jennifer A.

Interaction of chikungunya virus glycoproteins with macrophage factors controls virion production

EMBO JOURNAL

IF8.3

2024-09-11

OAAI

Yao, Zhenlan; Ramachandran, Sangeetha; Huang, Serina; Kim, Erin; Jami-Alahmadi, Yasaman; Kaushal, Prashant; Bouhaddou, Mehdi; Wohlschlegel, James A.; Li, Melody M. H.

CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells E3泛素连接酶的CRISPR-Cas9筛选将TRAF2和UHRF1鉴定为原代人T细胞中HIV潜伏期的调节剂

MBIO

IF4.7

2024-04-10

OAAI

Rathore, Ujjwal; Haas, Paige; Kumar, Vigneshwari Easwar; Hiatt, Joseph; Haas, Kelsey M.; Bouhaddou, Mehdi; Swaney, Danielle L.; Stevenson, Erica; Zuliani-Alvarez, Lorena; McGregor, Michael J.; Turner-Groth, Autumn; Ochieng' Olwal, Charles; Bediako, Yaw; Braberg, Hannes; Soucheray, Margaret; Ott, Melanie; Eckhardt, Manon; Hultquist, Judd F.; Marson, Alexander; Kaake, Robyn M.; Krogan, Nevan J.

Targeting CDK1/2-driven mechanisms of resistance to BRAF and EGFR inhibition in BRAF(V600E) colorectal cancer restores therapeutic response

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Coppe, Jean-Philippe; Munoz, Denise P.; Atreya, Chloe E.; Hwang, Yeonjoo; Bouhaddou, Mehdi; Heinrich, Louise E.; Naser, Mohammad; Zakraoui, Ons; Pirker, Roxana; Guha, Rupa; Moelders, Christina; Scapozza, Alessandro; Schwarzer, Cecilia; Phillips, Layla; Wang, Changjun; van 't Veer, Laura; Steri, Veronica; VandenBerg, Scott R.

Hepatitis C virus infects and perturbs liver stem cells

MBIO

IF4.7

2023-12-19

OAAI

Meyers, Nathan L.; Ashuach, Tal; Lyons, Danielle E.; Khalid, Mir M.; Simoneau, Camille R.; Erickson, Ann L.; Bouhaddou, Mehdi; Nguyen, Thong T.; Kumar, G. Renuka; Taha, Taha Y.; Natarajan, Vaishaali; Baron, Jody L.; Neff, Norma; Zanini, Fabio; Mahmoudi, Tokameh; Quake, Stephen R.; Krogan, Nevan J.; Cooper, Stewart; Mcdevitt, Todd C.; Yosef, Nir; Ott, Melanie

Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-11-15

OAAI

Chong, Stephen Jun Fei; Zhu, Fen; Dashevsky, Olga; Mizuno, Rin; Lai, Jolin X. H.; Hackett, Liam; Ryan, Christine E.; Collins, Mary C.; Iorgulescu, J. Bryan; Guieze, Romain; Penailillo, Johany; Carrasco, Ruben; Hwang, Yeonjoo C.; Munoz, Denise P.; Bouhaddou, Mehdi; Lim, Yaw Chyn; Wu, Catherine J.; Allan, John N.; Furman, Richard R.; Goh, Boon Cher; Pervaiz, Shazib; Coppe, Jean-Philippe; Mitsiades, Constantine S.; Davids, Matthew S.

Defining blood-induced microglia functions in neurodegeneration through multiomic profiling

NATURE IMMUNOLOGY

IF27.6

2023-06-08

OAAI

Mendiola, Andrew S.; Yan, Zhaoqi; Dixit, Karuna; Johnson, Jeffrey R.; Bouhaddou, Mehdi; Meyer-Franke, Anke; Shin, Min-Gyoung; Yong, Yu; Agrawal, Ayushi; MacDonald, Eilidh; Muthukumar, Gayathri; Pearce, Clairice; Arun, Nikhita; Cabriga, Belinda; Meza-Acevedo, Rosa; Alzamora, Maria del Pilar S.; Zamvil, Scott S.; Pico, Alexander R.; Ryu, Jae Kyu; Krogan, Nevan J.; Akassoglou, Katerina

Current proteomics methods applicable to dissecting the DNA damage response

NAR CANCER

IF3.2

2023-05-19

OAAI

Muralidharan, Monita; Krogan, Nevan J.; Bouhaddou, Mehdi; Kim, Minkyu

Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms

ELIFE

IF0

2023-01-24

OAAI

Chan, Gary K. L.; Maisel, Samantha; Hwang, Yeonjoo C.; Pascual, Bryan C.; Wolber, Rebecca R. B.; Vu, Phuong; Patra, Krushna C.; Bouhaddou, Mehdi; Kenerson, Heidi L.; Lim, Huat C.; Long, Donald; Yeung, Raymond S.; Sethupathy, Praveen; Swaney, Danielle L.; Krogan, Nevan J.; Turnham, Rigney E.; Riehle, Kimberly J.; Scott, John D.; Bardeesy, Nabeel; Gordan, John D.

Network modeling suggests HIV infection phenocopies PI3K-AKT pathway mutations to enhance HPV-associated cervical cancer

MOLECULAR OMICS

IF2.4

2023-01-01

PREAI

Olwal, Charles Ochieng; Fabius, Jacqueline M.; Zuliani-Alvarez, Lorena; Eckhardt, Manon; Kyei, George Boateng; Quashie, Peter Kojo; Krogan, Nevan J.; Bouhaddou, Mehdi; Bediako, Yaw

Network inference from perturbation time course data

NPJ SYSTEMS BIOLOGY AND APPLICATIONS

IF3.5

2022-11-01

OAAI

Sarmah, Deepraj; Smith, Gregory R.; Bouhaddou, Mehdi; Stern, Alan D.; Erskine, James; Birtwistle, Marc R.

Leveraging modeling and simulation to optimize the therapeutic window for epigenetic modifier drugs 利用建模和仿真优化表观遗传修饰药物的治疗窗口

PHARMACOLOGY & THERAPEUTICS

IF12.5

2022-07-01

OAAI

Walz, Antje-Christine; Van De Vyver, Arthur J.; Yu, Li; Birtwistle, Marc R.; Krogan, Nevan J.; Bouhaddou, Mehdi

A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling

NATURE COMMUNICATIONS

IF15.7

2022-06-21

OAAI

Erdem, Cemal; Mutsuddy, Arnab; Bensman, Ethan M.; Dodd, William B.; Saint-Antoine, Michael M.; Bouhaddou, Mehdi; Blake, Robert C.; Gross, Sean M.; Heiser, Laura M.; Feltus, F. Alex; Birtwistle, Marc R.

A functional map of HIV-host interactions in primary human T cells

NATURE COMMUNICATIONS

IF15.7

2022-04-01

OAAI

Hiatt, Joseph; Hultquist, Judd F.; McGregor, Michael J.; Bouhaddou, Mehdi; Leenay, Ryan T.; Simons, Lacy M.; Young, Janet M.; Haas, Paige; Roth, Theodore L.; Tobin, Victoria; Wojcechowskyj, Jason A.; Woo, Jonathan M.; Rathore, Ujjwal; Cavero, Devin A.; Shifrut, Eric; Nguyen, Thong T.; Haas, Kelsey M.; Malik, Harmit S.; Doudna, Jennifer A.; May, Andrew P.; Marson, Alexander; Krogan, Nevan J.

Preclinical and randomized phase I studies of plitidepsin in adults with COVID-19

LIFE SCIENCE ALLIANCE

IF2.9

2022-01-10

OAAI

Varona, Jose F.; Landete, Pedro; Lopez-Martin, Jose A.; Estrada, Vicente; Paredes, Roger; Guisado-Vasco, Pablo; Fernandez de Orueta, Lucia; Torralba, Miguel; Fortun, Jesus; Vates, Roberto; Barberan, Jose; Clotet, Bonaventura; Ancochea, Julio; Carnevali, Daniel; Cabello, Noemi; Porras, Lourdes; Gijon, Paloma; Monereo, Alfonso; Abad, Daniel; Zuniga, Sonia; Sola, Isabel; Rodon, Jordi; Vergara-Alert, Julia; Izquierdo-Useros, Nuria; Fudio, Salvador; Jose Pontes, Maria; de Rivas, Beatriz; Giron de Velasco, Patricia; Nieto, Antonio; Gomez, Javier; Aviles, Pablo; Lubomirov, Rubin; Belgrano, Alvaro; Sopesen, Belen; White, Kris M.; Rosales, Romel; Yildiz, Soner; Reuschl, Ann-Kathrin; Thorne, Lucy G.; Jolly, Clare; Towers, Greg J.; Zuliani-Alvarez, Lorena; Bouhaddou, Mehdi; Obernier, Kirsten; McGovern, Briana L.; Rodriguez, M. Luis; Enjuanes, Luis; Fernandez-Sousa, Jose M.; Krogan, Nevan J.; Jimeno, Jose M.; Garcia-Sastre, Adolfo

Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer

JCI INSIGHT

IF6.1

2021-10-22

OAAI

Bouhaddou, Mehdi; Lee, Rex H.; Li, Hua; Bhola, Neil E.; O'Keefe, Rachel A.; Naser, Mohammad; Zhu, Tian Ran; Nwachuku, Kelechi; Duvvuri, Umamaheswar; Olshen, Adam B.; Roy, Ritu; Hechmer, Aaron; Bolen, Jennifer; Keysar, Stephen B.; Jimeno, Antonio; Mills, Gordon B.; Vandenberg, Scott; Swaney, Danielle L.; Johnson, Daniel E.; Krogan, Nevan J.; Grandis, Jennifer R.

研究方向