未登录 Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay 减弱核糖体负荷通过限制翻译依赖性mRNA衰变来改善mRNA的蛋白质输出 Bicknell, Alicia A.; Reid, David W.; Licata, Marissa C.; Jones, Adriana K.; Cheng, Yi Min; Li, Mengying; Hsiao, Chiaowen Joyce; Pepin, Christopher S.; Metkar, Mihir; Levdansky, Yevgen; Fritz, Brian R.; Andrianova, Elizaveta A.; Jain, Ruchi; Valkov, Eugene; Kohrer, Caroline; Moore, Melissa J. 分享 收藏
Translation-dependent and -independent mRNA decay occur through mutually exclusive pathways defined by ribosome density during T cell activation Mercier, Blandine C.; Labaronne, Emmanuel; Cluet, David; Guiguettaz, Laura; Fontrodona, Nicolas; Bicknell, Alicia; Corbin, Antoine; Wencker, Melanie; Aube, Fabien; Modolo, Laurent; Jouravleva, Karina; Auboeuf, Didier; Moore, Melissa J.; Ricci, Emiliano P. 分享 收藏
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Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1 Davis, Sarah M.; Hariharan, Vignesh N.; Lo, Agnes; Turanov, Anton A.; Echeverria, Dimas; Sousa, Jacquelyn; McHugh, Nicholas; Biscans, Annabelle; Alterman, Julia F.; Karumanchi, S. Ananth; Moore, Melissa J.; Khvorova, Anastasia 分享 收藏
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mRNA structure regulates protein expression through changes in functional half-life mRNA结构通过改变功能性半衰期调节蛋白表达 Mauger, David M.; Cabral, B. Joseph; Presnyak, Vladimir; Su, Stephen V.; Reid, David W.; Goodman, Brooke; Link, Kristian; Khatwani, Nikhil; Reynders, John; Moore, Melissa J.; McFadyen, Iain J. 分享 收藏
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Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines Hassett, Kimberly J.; Benenato, Kerry E.; Jacquinet, Eric; Lee, Aisha; Woods, Angela; Yuzhakov, Olga; Himansu, Sunny; Deterling, Jessica; Geilich, Benjamin M.; Ketova, Tatiana; Mihai, Cosmin; Lynn, Andy; McFadyen, Iain; Moore, Melissa J.; Senn, Joseph J.; Stanton, Matthew G.; Almarsson, Orn; Ciaramella, Giuseppe; Brito, Luis A. 分享 收藏
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RNAi modulation of placental sFLT1 for the treatment of preeclampsia Turanov, Anton A.; Lo, Agnes; Hassler, Matthew R.; Makris, Angela; Ashar-Patel, Ami; Alterman, Julia F.; Coles, Andrew H.; Haraszti, Reka A.; Roux, Loic; Godinho, Bruno M. D. C.; Echeverria, Dimas; Pears, Suzanne; Iliopoulos, Jim; Shanmugalingam, Renuka; Ogle, Robert; Zsengeller, Zsuzsanna K.; Hennessy, Annemarie; Karumanchi, S. Ananth; Moore, Melissa J.; Khvorova, Anastasia 分享 收藏
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MicroRNAs Enable mRNA Therapeutics to Selectively Program Cancer Cells to Self-Destruct Jain, Ruchi; Frederick, Josh P.; Huang, Eric Y.; Burke, Kristine E.; Mauger, David M.; Andrianova, Elizaveta A.; Farlow, Sam J.; Siddiqui, Summar; Pimentel, Jeffrey; Cheung-Ong, Kahlin; McKinney, Kristine M.; Kohrer, Caroline; Moore, Melissa J.; Chakraborty, Tirtha 分享 收藏
Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin Didiot, Marie-Cecile; Ferguson, Chantal M.; Ly, Socheata; Coles, Andrew H.; Smith, Abigail O.; Bicknell, Alicia A.; Hall, Lauren M.; Sapp, Ellen; Echeverria, Dimas; Pai, Athma A.; DiFiglia, Marian; Moore, Melissa J.; Hayward, Lawrence J.; Aronin, Neil; Khvorova, Anastasia 分享 收藏
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Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo Hassler, Matthew R.; Turanov, Anton A.; Alterman, Julia F.; Haraszti, Reka A.; Coles, Andrew H.; Osborn, Maire F.; Echeverria, Dimas; Nikan, Mehran; Salomon, William E.; Roux, Loic; Godinho, Bruno M. D. C.; Davis, Sarah M.; Morrissey, David V.; Zamore, Phillip D.; Karumanchi, S. Ananth; Moore, Melissa J.; Aronin, Neil; Khvorova, Anastasia 分享 收藏
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CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion Mou, Haiwei; Smith, Jordan L.; Peng, Lingtao; Yin, Hao; Moore, Jill; Zhang, Xiao-Ou; Song, Chun-Qing; Sheel, Ankur; Wu, Qiongqiong; Ozata, Deniz M.; Li, Yingxiang; Anderson, Daniel G.; Emerson, Charles P.; Sontheimer, Erik J.; Moore, Melissa J.; Weng, Zhiping; Xue, Wen 分享 收藏
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