Nigel G. J. Richards - Publications, H-index & Citations

Nigel G. J. Richards

Cardiff University

36H指数

198论文数

7.8K被引数

收录论文 67

发表时间

A Foundational Shift in Models for Enzyme Function 酶功能模型的基础性转变

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2025-04-25

OAAI

Klinman, Judith P.; Miller, Susan M.; Richards, Nigel G. J.

3D variability analysis reveals a hidden conformational change controlling ammonia transport in human asparagine synthetase

NATURE COMMUNICATIONS

IF15.7

2024-12-03

OAAI

Coricello, Adriana; Nardone, Alanya J.; Lupia, Antonio; Gratteri, Carmen; Vos, Matthijn; Chaptal, Vincent; Alcaro, Stefano; Zhu, Wen; Takagi, Yuichiro; Richards, Nigel G. J.

Arginine Kinase Activates Arginine for Phosphorylation by Pyramidalization and Polarization

ACS CATALYSIS

IF13.1

2024-04-16

OAAI

Falcioni, Fabio; Molt Jr, Robert W.; Jin, Yi; Waltho, Jonathan P.; Hay, Sam; Richards, Nigel G. J.; Blackburn, G. Michael

Reactivity and mechanism in chemical and synthetic biology

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2023-01-11

OAAI

Richards, Nigel G. J.; Bearne, Stephen L.; Goto, Yuki; Parker, Emily J.

Novel Dihydropyrimidinone Derivatives as Potential P-Glycoprotein Modulators

ACS OMEGA

IF4.3

2022-05-02

OAAI

Bijani, Sabera; Shaikh, Faraz; Mirza, Sheefa; Siu, Shirley Weng In; Jain, Nayan; Rawal, Rakesh; Richards, Nigel G. J.; Shah, Anamik; Radadiya, Ashish

Building better polymerases: Engineering the replication of expanded genetic alphabets

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-12-01

OAAI

Ouaray, Zahra; Benner, Steven A.; Georgiadis, Millie M.; Richards, Nigel G. J.

Tautomeric Equilibria of Nucleobases in the Hachimoji Expanded Genetic Alphabet

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2020-03-03

OAAI

Eberlein, Lukas; Beierlein, Frank R.; Hommes, Nico J. R. van Eikema; Radadiya, Ashish; Heil, Jochen; Benner, Steven A.; Clark, Timothy; Kast, Stefan M.; Richards, Nigel G. J.

High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity (vol 2, 345, 2019)

COMMUNICATIONS BIOLOGY

IF5.1

2019-11-22

OAAI

Zhu, Wen; Radadiya, Ashish; Bisson, Claudine; Wenzel, Sabine; Nordin, Brian E.; Martinez-Marquez, Francisco; Imasaki, Tsuyoshi; Sedelnikova, Svetlana E.; Coricello, Adriana; Baumann, Patrick; Berry, Alexandria H.; Nomanbhoy, Tyzoon K.; Kozarich, John W.; Jin, Yi; Rice, David W.; Takagi, Yuichiro; Richards, Nigel G. J.

High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity

COMMUNICATIONS BIOLOGY

IF5.1

2019-09-17

OAAI

Zhu, Wen; Radadiya, Ashish; Bisson, Claudine; Wenzel, Sabine; Nordin, Brian E.; Martinez-Marquez, Francisco; Imasaki, Tsuyoshi; Sedelnikova, Svetlana E.; Coricello, Adriana; Baumann, Patrick; Berry, Alexandria H.; Nomanbhoy, Tyzoon K.; KozarichHD, John W.; Jin, Yi; Rice, David W.; Takagi, Yuichiro; Richards, Nigel G. J.

PMP-diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis

CHEMICAL COMMUNICATIONS

IF4.2

2019-01-01

OAAI

Gao, Sisi; Liu, Huanting; de Crecy-Lagard, Valerie; Zhu, Wen; Richards, Nigel G. J.; Naismith, James H.

Chemoenzymatic Synthesis, Nanotization, and Anti-Aspergillus Activity of Optically Enriched Fluconazole Analogues

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2017-08-01

OAAI

Malhotra, Shashwat; Singh, Seema; Rana, Neha; Tomar, Shilpi; Bhatnagar, Priyanka; Gupta, Mohit; Singh, Suraj K.; Singh, Brajendra K.; Chhillar, Anil K.; Prasad, Ashok K.; Len, Christophe; Kumar, Pradeep; Gupta, Kailash C.; Varma, Anjani J.; Kuhad, Ramesh C.; Sharma, Gainda L.; Parmar, Virinder S.; Richards, Nigel G. J.

A Combined Experimental-Theoretical Study of the LigW-Catalyzed Decarboxylation of 5-Carboxyvanillate in the Metabolic Pathway for Lignin Degradation

ACS CATALYSIS

IF13.1

2017-06-30

OAAI

Sheng, Xiang; Zhu, Wen; Huddleston, Jamison; Xiang, Dao Fen; Raushel, Frank M.; Richards, Nigel G. J.; Himo, Fahmi

Toward an Expanded Genome: Structural and Computational Characterization of an Artificially Expanded Genetic Information System

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2017-06-08

OAAI

Richards, Nigel G. J.; Georgiadis, Millie M.

Assessing the Influence of Mutation on GTPase Transition States by Using X-ray Crystallography, 19F NMR, and DFT Approaches

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2017-05-24

OAAI

Jin, Yi; Molt, Robert W., Jr.; Pellegrini, Erika; Cliff, Matthew J.; Bowler, Matthew W.; Richards, Nigel G. J.; Blackburn, G. Michael; Waltho, Jonathan P.

Biological functions controlled by manganese redox changes in mononuclear Mn-dependent enzymes

BIOINORGANIC CHEMISTRY

IF0

2017-05-09

OAAI

Zhu, Wen; Richards, Nigel G. J.

Metal Fluorides as Analogues for Studies on Phosphoryl Transfer Enzymes

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2017-03-21

OAAI

Jin, Yi; Richards, Nigel G.; Waltho, Jonathan P.; Blackburn, G. Michael

Consecutive non-natural PZ nucleobase pairs in DNA impact helical structure as seen in 50 μs molecular dynamics simulations

NUCLEIC ACIDS RESEARCH

IF13.1

2017-02-28

OAAI

Molt, Robert W.; Georgiadis, Millie M., Jr.; Richards, Nigel G. J.

Synthesis and anti-inflammatory activity evaluation of novel triazolyl-isatin hybrids

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2016-05-05

OAAI

Sharma, Pramod K.; Balwani, Sakshi; Mathur, Divya; Malhotra, Shashwat; Singh, Brajendra K.; Prasad, Ashok K.; Len, Christophe; Van der Eycken, Erik V.; Ghosh, Balaram; Richards, Nigel G. J.; Parmar, Virinder S.

Microwave-Assisted, Metal-Free, Base-Mediated C-N Bond Formation/Cleavage: Synthesis of Benzimidazo[1,2-a]quinazoline Derivatives

ACS SUSTAINABLE CHEMISTRY & ENGINEERING

IF7.3

2016-03-11

PREAI

Kumar, Prashant; Singh, Anil K.; Bahadur, Vijay; Len, Christophe; Richards, Nigel G. J.; Parmar, Virinder S.; Van der Eycken, Erik V.; Singh, Brajendra K.

19FNMR and DFT Analysis Reveal Structural and Electronic Transition State Features for RhoA-Catalyzed GTP Hydrolysis

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2016-01-28

OAAI

Jin, Yi; Molt, Robert W., Jr.; Waltho, Jonathan P.; Richards, Nigel G. J.; Blackburn, G. Michael

研究方向