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W

William C. Hahn

Broad Institute of MIT and Harvard

147H指数
1.1K论文数
10.2W被引数
收录论文 329
发表时间
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A dependency map enhanced with next-generation 3D cancer models一张融合了新一代3D癌症模型的药物靶点互作图
errNature
IF48.5
err2026-08-05
err0
errOAAI
errJames V. Neiswender; Samuel Maffa; Lisa Brenan; Dina ElHarouni; Yejie Yun; Isabella Boyle; Kirsty Wienand; Haider Inam; Tate Bertea; Ashley Anderson; Megan Wong; Matias Enriquez; Evan Lenz; Beatriz Villafranca; Nora Shanks; Mary Hager; Nia Lloyd; Hannah Shadmany; Sarah J. Wie; Harry Liang; Konnor Yunghans; Xiaomeng Zhang; Lauren Golden; Hannah Harris; Serena Day; Philip Montgomery; Samantha Stokes; Ross M. Giglio; Cynthia Hajal; James R. Whittle; Guadalupe Garcia; Caitlin E. Mills; Mehdi Touat; Kristine Pelton; Hongyu Li; Prem Sai Prabhakar; Sonja Herter; Zoe Hoffmann Kamrat; Dan Gui; Julien Dilly; Chen Khuan Wong; Jimmy A. Guo; Sangita Pal; Yossef Baidi; Ryan Johnston; Daniel D. Brown; Sonam Bhatia; Peter S. Winter; Srivatsan Raghavan; Rameen Beroukhim; Eva Colas; David L. Spector; Adam J. Bass; Peter K. Sorger; Yu Chen; Sarah J. Hill; Steffi Oesterreich; Adrian V. Lee; Himisha Beltran; Jesse S. Boehm; Yuen-Yi Tseng; David E. Root; William C. Hahn; Andrew J. Aguirre; Catarina D. Campbell; Keith L. Ligon; Joshua M. Dempster; Tsukasa Shibue; Francisca Vazquez
err分享
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Editorial Expression of Concern: Creation of human tumour cells with defined genetic elements编辑意见关注：具有特定遗传元件的人类肿瘤细胞的创建
errNature
IF48.5
err2026-04-15
err0
PREAI
errWilliam C. Hahn; Christopher M. Counter; Ante S. Lundberg; Roderick L. Beijersbergen; Mary W. Brooks; Robert A. Weinberg
err分享
err收藏
SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activitySMARCB1错义突变体破坏SWI/SNF复合物的稳定性和重塑活性
errNature Communications
IF15.7
err2026-04-08
err0
errOAAI
errGarrett W. Cooper; Benjamin P. Lee; Won Jun Kim; Yongdong Su; Victor Z. Chen; Eliseo Salas; Xiaoping Yang; Robert E. Lintner; Federica Piccioni; Andrew O. Giacomelli; Thomas P. Howard; Pritha Bagchi; Karen N. Conneely; David E. Root; Bo Liang; James C. Gumbart; William C. Hahn; David U. Gorkin; Jaclyn A. Biegel; Susan N. Chi; Andrew L. Hong
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Ammonolysis Under NH3–Limiting Conditions as a Pathway to Improved LaTiO2N Water Splitting Photoanodes在NH3限制条件下进行氨解反应作为改善LaTiO2N水分解光阳极的途径
errACS Applied Energy Materials
IF5.5
err2025-10-27
err0
PREAI
errLi Wang; Mahya Salmanion; Rajesh Kandel; William Hahn; Guodong Rao; Zainab Najaf; Klaus van Benthem; R. David Britt; Frank E. Osterloh
err分享
err收藏
Dopant diffusion and segregation of iron in a near 45° (100) twist grain boundary in SrTiO3在SrTiO3中，铁在近45° (100) 扭转晶界处的掺杂扩散与偏析
errJournal of the American Ceramic Society
IF3.8
err2025-10-24
err0
errOAAI
errWilliam Hahn; Kazuaki Kawahara; Shun Sasano; Bin Feng; Naoya Shibata; Yuichi Ikuhara; Klaus van Benthem
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Iron Enrichment at Grain Boundaries in SrTiO3: Does It Stay or Does It Go?
errMicroscopy and Microanalysis
IF3
err2025-07-25
err0
errOAAI
errWilliam D Hahn; Bin Feng; Naoya Shibata; Yuichi Ikuhara; Klaus van Benthem
err分享
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A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors一种新构型蛋白质界面催化肿瘤中RASG12D天冬氨酸的共价抑制
errScience
IF45.8
err2025-07-24
err0
PREAI
errCaroline Weller; G. Leslie Burnett; Lingyan Jiang; Sujata Chakraborty; Dongyu Zhang; Nicole A. Vita; Julien Dilly; Eejung Kim; Benjamin Maldonato; Kyle Seamon; Diane F. Eilerts; Anthony Milin; Abby Marquez; Jessica Spradlin; Ciara Helland; Andrea Gould; Tamar Bar Ziv; Phuong Dinh; Shelby L. Steele; Zhican Wang; Yunming Mu; Seema Chugh; Hanrong Feng; Conner Hennessey; Junning Wang; Jennifer Roth; Matthew Rees; Melissa Ronan; Brian M. Wolpin; William C. Hahn; Matthew Holderfield; Zhengping Wang; Elena S. Koltun; Mallika Singh; Adrian L. Gill; Jacqueline A. M. Smith; Andrew J. Aguirre; Jingjing Jiang; John E. Knox; David Wildes
err分享
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Cancer Dependency Map Past and Present癌症依赖图谱：过去与现在
errANNUAL REVIEW OF CANCER BIOLOGY
IF6.1
err2025-04-11
err0
PREAI
errArafeh, Rand; Shibue, Tsukasa; Vazquez, Francisca; Hahn, William C.
err分享
err收藏
Electric field-induced defect redistribution along a near 23° (100) tilt grain boundary in SrTiO3
errJOURNAL OF THE AMERICAN CERAMIC SOCIETY
IF3.8
err2025-03-01
err0
errOAAI
errHahn, William; Lupini, Andrew R.; van Benthem, Klaus
err分享
err收藏
Flux synthesis of single crystal bismuth vanadate (BiVO4) nanowires and their visible light driven photocatalytic water oxidation properties熔盐法合成单晶钒酸铋(BiVO4)纳米线及其可见光驱动的光催化水氧化性能
errJOURNAL OF MATERIALS CHEMISTRY A
IF9.5
err2025-01-01
err0
PREAI
errXiao, Chengcan; Assavachin, Samutr; Hahn, William; Wang, Li; Osterloh, Frank E.
err分享
err收藏
The present and future of the Cancer Dependency Map癌症依赖图的现在和未来
errNATURE REVIEWS CANCER
IF66.8
err2024-10-28
err0
PREAI
errArafeh, Rand; Shibue, Tsukasa; Dempster, Joshua M.; Hahn, William C.; Vazquez, Francisca
err分享
err收藏
Scalable, compressed phenotypic screening using pooled perturbations
errNATURE BIOTECHNOLOGY
IF41.7
err2024-10-07
err0
errOAAI
errLiu, Nuo; Kattan, Walaa E.; Mead, Benjamin E.; Kummerlowe, Conner; Cheng, Thomas; Ingabire, Sarah; Cheah, Jaime H.; Soule, Christian K.; Vrcic, Anita; Mcininch, Jane K.; Triana, Sergio; Guzman, Manuel; Dao, Tyler T.; Peters, Joshua M.; Lowder, Kristen E.; Crawford, Lorin; Amini, Ava P.; Blainey, Paul C.; Hahn, William C.; Cleary, Brian; Bryson, Bryan; Winter, Peter S.; Raghavan, Srivatsan; Shalek, Alex K.
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Deep mutational scanning of SMARCB1 identifies missense mutants that destabilize SWI/SNF complex stability and diminish remodeling activity
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errCooper, Garrett; Lee, Benjamin; Kim, Won; Salas, Eliseo; Su, Yongdong; Chen, Victor; Yang, Xiaoping; Lintner, Robert; Piccioni, Federica; Giacomelli, Andrew; Howard, Thomas; Conneely, Karen; Root, David; Hahn, William; Gorkin, David; Liang, Bo; Biegel, Jaclyn; Chi, Susan; Hong, Andrew
err分享
err收藏
Editor's Note: Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells
errCANCER RESEARCH
IF16.6
err2024-08-01
err0
errOAAI
errBerger, Raanan; Febbo, Phillip G.; Majumder, Pradip K.; Zhao, Jean J.; Mukherjee, Shayan; Signoretti, Sabina; Campbell, K. Thirza; Sellers, William R.; Roberts, Thomas M.; Loda, Massimo; Golub, Todd R.; Hahn, William C.
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err收藏
Combinatorial genetic screens to map synthetic lethal interactions and identify new cancer drug targets in KRAS mutant cancers
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2024-06-10
err0
PREAI
errArafeh, Rand; Chang, Laura; Sawyer, Lydia; Wang, Helen; McFarland, James; Dempster, Joshua; DeWeirdt, Peter; Doench, John; Hahn, William C.
err分享
err收藏
Combinatorial genetic screens to map synthetic lethal interactions and identify new cancer drug targets in KRAS mutant cancers
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2024-06-10
err0
PREAI
errArafeh, Rand; Chang, Laura; Sawyer, Lydia; Wang, Helen; McFarland, James; Dempster, Joshua; DeWeirdt, Peter; Doench, John; Hahn, William C.
err分享
err收藏
On knowing a gene: A distributional hypothesis of gene function关于认识基因: 基因功能的分布假说
errCELL SYSTEMS
IF7.7
err2024-06-01
err0
errOAAI
errKwon, Jason J.; Pan, Joshua; Gonzalez, Guadalupe; Hahn, William C.; Zitnik, Marinka
err分享
err收藏
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-04-08
err0
errOAAI
errMittal, Karuna; Cooper, Garrett W.; Lee, Benjamin P.; Su, Yongdong; Skinner, Katie T.; Shim, Jenny; Jonus, Hunter C.; Kim, Won Jun; Doshi, Mihir; Almanza, Diego; Kynnap, Bryan D.; Christie, Amanda L.; Yang, Xiaoping; Cowley, Glenn S.; Leeper, Brittaney A.; Morton, Christopher L.; Dwivedi, Bhakti; Lawrence, Taylor; Rupji, Manali; Keskula, Paula; Meyer, Stephanie; Clinton, Catherine M.; Bhasin, Manoj; Crompton, Brian D.; Tseng, Yuen-Yi; Bohm, Jesse S.; Ligon, Keith L.; Root, David E.; Murphy, Andrew J.; Weinstock, David M.; Gokhale, Prafulla C.; Spangle, Jennifer M.; Rivera, Miguel N.; Mullen, Elizabeth A.; Stegmaier, Kimberly; Goldsmith, Kelly C.; Hahn, William C.; Hong, Andrew L.
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RETRACTION: Cancer-Associated PP2A Aα Subunits Induce Functional Haploinsufficiency and Tumorigenicity (Retraction of Vol 65, Pg 8183, 2005)
errCANCER RESEARCH
IF16.6
err2024-03-15
err0
errOAAI
errChen, Wen; Arroyo, Jason D.; Timmons, Jamie C.; Possemato, Richard; Hahn, William C.
err分享
err收藏
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB (vol 16, pg 286, 2010)
errNATURE MEDICINE
IF50
err2024-02-21
err0
errOAAI
errMin, Junxia; Zaslavsky, Alexander; Fedele, Giuseppe; Mclaughlin, Sara. K.; Reczek, Elizabeth. E.; De Raedt, Thomas; Guney, Isil; Strochlic, David. E.; Macconaill, Laura. E.; Beroukhim, Rameen; Bronson, Roderick. T.; Ryeom, Sandra; Hahn, William. C.; Loda, Massimo; Cichowski, Karen
err分享
err收藏

研究方向

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