Geuijen, Cecile; Tacken, Paul; Wang, Liang-Chuan; Klooster, Rinse; van Loo, Pieter Fokko; Zhou, Jing; Mondal, Arpita; Liu, Yao-bin; Kramer, Arjen; Condamine, Thomas; Volgina, Alla; Hendriks, Linda J. A.; van der Maaden, Hans; Rovers, Eric; Engels, Steef; Fransen, Floris; den Blanken-Smit, Renate; Zondag-van der Zande, Vanessa; Basmeleh, Abdul; Bartelink, Willem; Kulkarni, Ashwini; Marissen, Wilfred; Huang, Cheng-Yen; Hall, Leslie; Harvey, Shane; Kim, Soyeon; Martinez, Marina; O'Brien, Shaun; Moon, Edmund; Albelda, Steven; Kanellopoulou, Chrysi; Stewart, Shaun; Nastri, Horacio; Bakker, Alexander B. H.; Scherle, Peggy; Logtenberg, Ton; Hollis, Gregory; de Kruif, John; Huber, Reid; Mayes, Patrick A.; Throsby, Mark

MCLA-145 IS A BISPECIFIC IGG1 ANTIBODY THAT INHIBITS PD-1/PD-L1 SIGNALING WHILE SIMULTANEOUSLY ACTIVATING CD137 SIGNALING ON T CELLS

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2020-11-090

OAAI

Tacken, Paul; Wang, Liang-chuan; Klooster, Rinse; Van Loo, Pieter Fokko; Zhou, Jing; Mondal, Arpita; Liu, Yao-Bin; Kramer, Arjen; Condamine, Thomas; Volgina, Alla; Hendriks, Linda; van der Maaden, Hans; Rovers, Eric; Engels, Steef; Fransen, Floris; den Blanken-Smit, Renate; Zondag-van der Zande, Vanessa; Basmeleh, Abdul; Bartelink, Willem; Kulkarni, Ashwini; Marissen, Wilfred; Huang, Cheng-Yen; Hall, Leslie; Harvey, Shane; Kanellopoulou, Chrysi; Stewart, Shaun; Nastri, Horacio; Bakker, Lex; Logtenberg, Ton; Plyte, Simon; Mayes, Patrick; Throsby, Mark; Geuijen, Cecile

Hydrogen Exchange Mass Spectrometry Guided Docking Generates Atomic Resolution Epitopes for Single-Chain Camelid Antibody-Antigen Complexes

BIOPHYSICAL JOURNAL

IF3.1

2019-02-010

OAAI

Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-03-0125

OAAI

A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission

新型自噬/线粒体自噬抑制剂莲心碱通过DNM1L-mediated线粒体分裂使乳腺癌细胞对化疗敏感

AUTOPHAGY

IF14.3

2015-08-14219

OAAI

Discovery of sulfonamide-piperidinones as potent inhibitors of the MDM2-p53 protein-protein interaction

CANCER RESEARCH

IF16.6

2015-08-011

PRE

The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic Agents

MDM2抑制剂AMG 232显示出强大的抗肿瘤功效，并增强了p53-Inducing细胞毒性剂的活性

MOLECULAR CANCER THERAPEUTICS

IF5.5

2015-03-09125

OAAI

Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2-p53 Interaction

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-12-0463

PREAI

Rew, Yosup; Sun, Daqing; Yan, Xuelei; Beck, Hilary P.; Canon, Jude; Chen, Ada; Duquette, Jason; Eksterowicz, John; Fox, Brian M.; Fu, Jiasheng; Gonzalez, Ana Z.; Houze, Jonathan; Huang, Xin; Jiang, Min; Jin, Lixia; Li, Yihong; Li, Zhihong; Ling, Yun; Lo, Mei-Chu; Long, Alexander M.; McGee, Lawrence R.; McIntosh, Joel; Oliner, Jonathan D.; Osgood, Tao; Saiki, Anne Y.; Shaffer, Paul; Wang, Yu Chung; Wortman, Sarah; Yakowec, Peter; Ye, Qiuping; Yu, Dongyin; Zhao, Xiaoning; Zhou, Jing; Medina, Julio C.; Olson, Steven H.

Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 Interaction

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2014-07-0924

OAAI

Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-03-2761

PREAI

Gonzalez, Ana Z.; Li, Zhihong; Beck, Hilary P.; Canon, Jude; Chen, Ada; Chow, David; Duquette, Jason; Eksterowicz, John; Fox, Brian M.; Fu, Jiasheng; Huang, Xin; Houze, Jonathan; Jin, Lixia; Li, Yihong; Ling, Yun; Lo, Mei-Chu; Long, Alexander M.; McGee, Lawrence R.; McIntosh, Joel; Oliner, Jonathan D.; Osgood, Tao; Rew, Yosup; Saiki, Anne Y.; Shaffer, Paul; Wortman, Sarah; Yakowec, Peter; Yan, Xuelei; Ye, Qiuping; Yu, Dongyin; Zhao, Xiaoning; Zhou, Jing; Olson, Steven H.; Sun, Daqing; Medina, Julio C.

Jing Zhou

个人简介

教育背景

工作经历

荣誉奖项

研究方向