未登录 Deep PIM kinase substrate profiling reveals new rational cotherapeutic strategies for acute myeloid leukemia Joglekar, Tejashree; Chin, Alexander; Voskanian-Kordi, Alin; Baek, Seungchul; Raja, Azim; Rege, Apurv; Huang, Weiliang; Kane, Maureen; Laiho, Marikki; Webb, Thomas R.; Fan, Xiaoxuan; Rubenstein, Michael; Bieberich, Charles J.; Li, Xiang 分享 收藏
Mechanisms of therapeutic vulnerability of mismatch repair defective cancers to RNA polymerase I inhibitors Laiho, Marikki; Fan, Wenjun; Liu, Hester; Stachelek, Gregory C.; Begum, Asma; Davis, Catherine E.; Dorado, Tony; de Leon, Pablo; Rajeshkumar, N. V.; Barrow, James C. 分享 收藏
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Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress Pitts, Stephanie; Liu, Hester; Ibrahim, Adel; Garg, Amit; Felgueira, Catarina Mendes; Begum, Asma; Fan, Wenjun; Teh, Selina; Low, Jin-Yih; Ford, Brittany; Schneider, David A.; Hay, Ronald; Laiho, Marikki 分享 收藏
Persistent CAD activity in memory CD8+ T cells supports rRNA synthesis and ribosomal biogenesis required at rechallenge Claiborne, Michael D.; Sengupta, Srona; Zhao, Liang; Arwood, Matthew L.; Sun, Im-Meng; Wen, Jiayu; Thompson, Elizabeth A.; Mitchell-Flack, Marisa; Laiho, Marikki; Powell, Jonathan D. 分享 收藏
Discovery and Evaluation of Novel Angular Fused Pyridoquinazolinonecarboxamides as RNA Polymerase I Inhibitors Dorado, Tony E.; de Leon, Pablo; Begum, Asma; Liu, Hester; Chen, Daming; Rajeshkumar, N., V; Rey-Rodriguez, Romain; Hoareau-Aveilla, Coralie; Alcouffe, Chantal; Laiho, Marikki; Barrow, James C. 分享 收藏
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Reply to: Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos Hamalainen, Riikka H.; Landoni, Juan C.; Ahlqvist, Kati J.; Goffart, Steffi; Ryytty, Sanna; Rahman, M. Obaidur; Brilhante, Virginia; Icay, Katherine; Hautaniemi, Sampsa; Wang, Liya; Laiho, Marikki; Suomalainen, Anu 分享 收藏
Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias (vol 1, pg 958, 2019) Hamalainen, Riikka H.; Landoni, Juan C.; Ahlqvist, Kati J.; Goffart, Steffi; Ryytty, Sanna; Rahman, M. Obaidur; Brilhante, Virginia; Icay, Katherine; Hautaniemi, Sampsa; Wang, Liya; Laiho, Marikki; Suomalainen, Anu 分享 收藏
Equity and diversity in academic medicine: a perspective from the JCI editors Resar, Linda M. S.; Jaffee, Elizabeth M.; Armanios, Mary; Jackson, Sarah; Azad, Nilofer S.; Horton, Maureen R.; Kaplan, Mariana J.; Laiho, Marikki; Maus, Marcela V.; Sumner, Charlotte J.; Wheelan, Sarah J.; Wills-Karp, Marsha 分享 收藏
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Novel Assay to Detect RNA Polymerase I Activity In Vivo Guner, Gunes; Sirajuddin, Paul; Zheng, Qizhi; Bai, Baoyan; Brodie, Alexandra; Liu, Hester; af Hallstrom, Taija; Kulac, Ibrahim; Laiho, Marikki; De Marzo, Angelo M. 分享 收藏
Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A Kara, Bulent; Koroglu, Cigdem; Peltonen, Karita; Steinberg, Ruchama C.; Genc, Hulya Maras; Holtta-Vuori, Maarit; Guven, Ayse; Kanerva, Kristiina; Kotil, Tugba; Solakoglu, Seyhun; Zhou, You; Olkkonen, Vesa M.; Ikonen, Elina; Laiho, Marikki; Tolun, Aslihan 分享 收藏
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Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication Balistreri, Giuseppe; Viiliainen, Johanna; Turunen, Mikko; Diaz, Raquel; Lyly, Lauri; Pekkonen, Pirita; Rantala, Juha; Ojala, Krista; Sarek, Grzegorz; Teesalu, Mari; Denisova, Oxana; Peltonen, Karita; Julkunen, Ilkka; Varjosalo, Markku; Kainov, Denis; Kallioniemi, Olli; Laiho, Marikki; Taipale, Jussi; Hautaniemi, Sampsa; Ojala, Paivi M. 分享 收藏
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