Karlene A. Cimprich - Publications, H-index & Citations

Karlene A. Cimprich

Harvard Medical School

50H指数

101论文数

1.8W被引数

收录论文 55

发表时间

AAV-mediated genome editing is influenced by the formation of R-loops

MOLECULAR THERAPY

IF12

2024-12-01

PREAI

Puzzo, Francesco; Crossley, Magdalena P.; Goswami, Aranyak; Zhang, Feijie; Pekrun, Katja; Garzon, Jada L.; Cimprich, Karlene A.; Kay, Mark A.

HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

MOLECULAR CELL

IF16.6

2024-08-01

PREAI

Bai, Gongshi; Endres, Theresa; Kuhbacher, Ulrike; Mengoli, Valentina; Greer, Briana H.; Peacock, Emma M.; Newton, Matthew D.; Stanage, Tyler; Dello Stritto, Maria Rosaria; Lungu, Roxana; Crossley, Magdalena P.; Sathirachinda, Ataya; Cortez, David; Boulton, Simon J.; Cejka, Petr; Eichman, Brandt F.; Cimprich, Karlene A.

The crosstalk between DNA repair and immune responses

MOLECULAR CELL

IF16.6

2023-10-01

PREAI

Cimprich, Karlene A.; Li, Guo-Min; Demaria, Sandra; Gekara, Nelson O.; Zha, Shan; Chen, Qianming

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Sobeck, A; Stone, S; Costanzo, V; de Graaf, B; Reuter, T; de Winter, J; Wallisch, M; Akkari, Y; Olson, S; Wang, WD; Joenje, H; Christian, JL; Lupardus, PJ; Cimprich, KA; Gautier, J; Hoatlin, ME

Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids 转录复制冲突的直接可视化揭示了复制后的DNA:RNA杂种

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-03-02

OAAI

Stoy, Henriette; Zwicky, Katharina; Kuster, Danina; Lang, Kevin S.; Krietsch, Jana; Crossley, Magdalena P.; Schmid, Jonas A.; Cimprich, Karlene A.; Merrikh, Houra; Lopes, Massimo

Walking a tightrope The complex balancing act of R-loops in genome stability 走钢丝基因组稳定性中R环的复杂平衡行为

MOLECULAR CELL

IF16.6

2022-06-01

112

OAAI

Brickner, Joshua R.; Garzon, Jada L.; Cimprich, Karlene A.

Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA-DNA hybrid imaging

JOURNAL OF CELL BIOLOGY

IF6.4

2021-07-07

OAAI

Crossley, Magdalena P.; Brickner, Joshua R.; Song, Chenlin; Zar, Su Mon Thin; Maw, Su S.; Chedin, Frederic; Tsai, Miaw-Sheue; Cimprich, Karlene A.

Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2021-06-01

OAAI

Mehibel, Manal; Xu, Yu; Li, Caiyun G.; Moon, Eui Jung; Thakkar, Kaushik N.; Diep, Anh N.; Kim, Ryan K.; Bloomstein, Joshua D.; Xiao, Yiren; Bacal, Julien; Saldivar, Joshua C.; Le, Quynh-Thu; Cimprich, Karlene A.; Rankin, Erinn B.; Giaccia, Amato J.

qDRIP: a method to quantitatively assess RNA-DNA hybrid formation genome-wide

NUCLEIC ACIDS RESEARCH

IF13.1

2020-06-16

OAAI

Crossley, Magdalena P.; Bocek, Michael J.; Hamperl, Stephan; Swigut, Tomek; Cimprich, Karlene A.

HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis

MOLECULAR CELL

IF16.6

2020-06-01

133

OAAI

Bai, Gongshi; Kermi, Chames; Stoy, Henriette; Schiltz, Carl J.; Bacal, Julien; Zaino, Angela M.; Hadden, M. Kyle; Eichman, Brandt F.; Lopes, Massimo; Cimprich, Karlene A.

R-Loops as Cellular Regulators and Genomic Threats R环作为细胞调节因子和基因组威胁

MOLECULAR CELL

IF16.6

2019-02-01

502

OAAI

Crossley, Madzia P.; Bocek, Michael; Cimprich, Karlene A.

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis

CELL REPORTS

IF6.9

2019-01-01

OAAI

Li, Caiyun G.; Mahon, Cathal; Sweeney, Nathaly M.; Verschueren, Erik; Kantamani, Vivek; Li, Dan; Hennigs, Jan K.; Marciano, David P.; Diebold, Isabel; Abu-Halawa, Ossama; Elliott, Matthew; Sa, Silin; Guo, Feng; Wang, Lingli; Cao, Aiqin; Guignabert, Christophe; Sollier, Julie; Nickel, Nils P.; Kaschwich, Mark; Cimprich, Karlene A.; Rabinovitch, Marlene

Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dynamically Adjust Global DNA Synthesis Rates

CELL SYSTEMS

IF7.7

2018-07-01

OAAI

Daigh, Leighton H.; Liu, Chad; Chung, Mingyu; Cimprich, Karlene A.; Meyer, Tobias

Faulty replication can sting

NATURE

IF48.5

2018-04-18

PREAI

Crossley, Madzia P.; Cimprich, Karlene A.