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J

Jeffrey Hill

agency for science technology & research (a*star)
H指数:30
被引数:2,617

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Cell-based high-throughput screening using a target–NanoLuc fusion construct to identify molecular glue degraders of c-Myc oncoprotein

基于细胞的高通量筛选，使用靶向-NanoLuc融合构建体来识别c-Myc癌蛋白的分子胶降解剂

RSC Chem. Biol.
IF3.1
2025-09-300
OAAI
Muyu Xu †; Jinying Qiu ‡; Lin Tan † ‡; Jiayu Xu; Yi Wang; Wenyue Kong †; Hongda Liao †; Anran Chen †; Xiaolan Chen †; Jiying Zhang; Cookson K. C. Chiu; Meiying Zhang; Yingying Tian; Caohui Li; Biao Ma; Leiming Wang; Jingpeng Fu; Seung H. Choi §; Jeffrey Hill; Weijun Shen ¶
Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2021-11-0110
PRE
Ng, Pearly Shuyi; Foo, Klement; Sim, Sandra; Wang, Gang; Huang, Chuhui; Tan, Li Hong; Poulsen, Anders; Liu, Boping; Tee, Doris Hui Ying; Ahmad, Nur Huda Binte; Wang, Sifang; Ke, Zhiyuan; Lee, May Ann; Kwek, Zekui P.; Joy, Joma; Anantharajan, Jothi; Baburajendran, Nithya; Pendharkar, Vishal; Manoharan, Vithya; Vuddagiri, Susmitha; Sangthongpitag, Kanda; Hill, Jeffrey; Keller, Thomas H.; Hung, Alvin W.
Topography of transcriptionally active chromatin in glioblastoma
SCIENCE ADVANCES
IF12.5
2021-04-3014
OAAI
Xu, Liang; Chen, Ye; Huang, Yulun; Sandanaraj, Edwin; Yu, John S.; Lin, Ruby Yu-Tong; Dakle, Pushkar; Ke, Xin-Yu; Chong, Yuk Kien; Koh, Lynnette; Mayakonda, Anand; Nacro, Kassoum; Hill, Jeffrey; Huang, Mo-Li; Gery, Sigal; Lim, See Wee; Huang, Zhengyun; Xu, Ying; Chen, Jianxiang; Bai, Longchuan; Wang, Shaomeng; Wakimoto, Hiroaki; Yeo, Tseng Tsai; Ang, Beng Ti; Muschen, Markus; Tang, Carol; Tan, Tuan Zea; Koeffler, H. Phillip
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2
NEURON
IF15
2020-07-0132
OAAI
Escande-Beillard, Nathalie; Loh, Abigail; Saleem, Sahar N.; Kanata, Kohei; Hashimoto, Yui; Altunoglu, Umut; Metoska, Artina; Grandjean, Joanes; Ng, Fui Mee; Pomp, Oz; Baburajendran, Nithya; Wong, Joyner; Hill, Jeffrey; Beillard, Emmanuel; Cozzone, Patrick; Zaki, Maha; Kayserili, Hulya; Hamada, Hiroshi; Shiratori, Hidetaka; Reversade, Bruno
Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-01-0710
PREAI
Kwiatkowski, Jacek; Liu, Boping; Pang, Shermaine; Ahmad, Nur Huda Binte; Wang, Gang; Poulsen, Anders; Yang, Haiyan; Poh, Yong Rui; Tee, Doris Hui Ying; Ong, Esther; Retna, Priya; Dinie, Nurul; Kwek, Perlyn; Wee, John Liang Kuan; Manoharan, Vithya; Low, Choon Bing; Seah, Peck Gee; Pendharkar, Vishal; Sangthongpitag, Kanda; Joy, Joma; Baburajendran, Nithya; Jansson, Anna Elisabet; Nacro, Kassoum; Hill, Jeffrey; Keller, Thomas H.; Hung, Alvin W.
Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells
MOLECULAR CANCER THERAPEUTICS
IF5.5
2019-09-0338
OAAI
Anantharajan, Jothi; Zhou, Hengbo; Zhang, Lingdi; Hotz, Taylor; Vincent, Melanie Y.; Blevins, Melanie A.; Jansson, Anna E.; Kuan, John Wee Liang; Ng, Elizabeth Yihui; Yeo, Yee Khoon; Baburajendran, Nithya; Lin, Grace; Hung, Alvin W.; Joy, Joma; Patnaik, Samarjit; Marugan, Juan; Rudra, Pratyaydipta; Ghosh, Debashis; Hill, Jeffrey; Keller, Thomas H.; Zhao, Rui; Ford, Heide L.; Kang, CongBao
Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3 (vol 6, pg 978, 2019)
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2019-07-090
OAAI
Huang, Chuhui; Liew, Si Si; Lin, Grace R.; Poulsen, Anders; Ang, Melgious J. Y.; Chia, Brian C. S.; Chew, Sin Yin; Kwek, Zekui P.; Wee, John L. K.; Ong, Esther H.; Retna, Priya; Baburajendran, Nithya; Li, Rong; Yu, Weixuan; Koh-Stenta, Xiaoying; Ngo, Anna; Manesh, Sravanthy; Fulwood, Justina; Ke, Zhiyuan; Chung, Hwa Hwa; Sepramaniam, Sugunavathi; Chew, Xin Hui; Dinie, Nurul; Lee, May Ann; Chew, Yun Shan; Low, Choon Bing; Pendharkar, Vishal; Manoharan, Vithya; Vuddagiri, Susmitha; Sangthongpitag, Kanda; Joy, Joma; Matter, Alex; Hill, Jeffrey; Keller, Thomas H.; Foo, Klement
Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2019-05-2326
OAAI
Huang, Chuhui; Liew, Si Si; Lin, Grace R.; Poulsen, Anders; Ang, Melgious J. Y.; Chia, Brian C. S.; Chew, Sin Yin; Kwek, Zekui P.; Wee, John L. K.; Ong, Esther H.; Retna, Priya; Baburajendran, Nithya; Li, Rong; Yu, Weixuan; Koh-Stenta, Xiaoying; Ngo, Anna; Manesh, Sravanthy; Fulwood, Justina; Ke, Zhiyuan; Chung, Hwa Hwa; Sepramaniam, Sugunavathi; Chew, Xin Hui; Dinie, Nurul; Lee, May Ann; Chew, Yun Shan; Low, Choon Bing; Pendharkar, Vishal; Manoharan, Vithya; Vuddagiri, Susmitha; Sangthongpitag, Kanda; Joy, Joma; Matter, Alex; Hill, Jeffrey; Keller, Thomas H.; Foo, Klement
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2018-07-0545
OAAI
Liu, Bee Hui; Jobichen, Chacko; Chia, C. S. Brian; Chan, Tim Hon Man; Tang, Jing Ping; Chung, Theodora X. Y.; Li, Jia; Poulsen, Anders; Hung, Alvin W.; Koh-Stenta, Xiaoying; Tan, Yaw Sing; Verma, Chandra S.; Tan, Hong Kee; Wu, Chan-Shuo; Li, Feng; Hill, Jeffrey; Joy, Joma; Yang, Henry; Chai, Li; Sivaraman, J.; Tenen, Daniel G.
Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-04-2422
PREAI
Kwiatkowski, Jacek; Liu, Boping; Tee, Doris Hui Ying; Chen, Guoying; Ahmad, Nur Huda Binte; Wong, Yun Xuan; Poh, Zhi Ying; Ang, Shi Hua; Tan, Eldwin Sum Wai; Ong, Esther H. Q.; Dinie, Nurul; Poulsen, Anders; Pendharkar, Vishal; Sangthongpitag, Kanda; Lee, May Ann; Sepramaniam, Sugunavathi; Ho, Soo Yei; Cherian, Joseph; Hill, Jeffrey; Keller, Thomas H.; Hung, Alvin W.
Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-04-2344
PREAI
Yang, Haiyan; Chennamaneni, Lohitha Rao; Ho, Melvyn Wai Tuck; Ang, Shi Hua; Tan, Eldwin Sum Wai; Jeyaraj, Duraiswamy Athisayamani; Yeap, Yoon Sheng; Liu, Boping; Ong, Esther Hq; Joy, Joma Kanikadu; Wee, John Liang Kuan; Kwek, Perlyn; Retna, Priya; Dinie, Nurul; Thuy Thi Hanh Nguyen; Tai, Shi Jing; Manoharan, Vithya; Pendharkar, Vishal; Low, Choon Bing; Chew, Yun Shan; Vuddagiri, Susmitha; Sanfthongpitag, Kanda; Choong, Meng Ling; Lee, May Ann; Kannan, Srinivasaraghavan; Verma, Chandra S.; Poulsen, Anders; Lim, Sharon; Chuah, Charles; Ong, Tiong Sin; Hill, Jeffrey; Matter, Alex; Nacro, Kassoum

研究方向

暂未获取到该数据
A
Anders Poulsen
H 指数:32论文数:106被引数:3,000
T
Thomas H. Keller
H 指数:46论文数:200被引数:9,080
J
Joma Joy
H 指数:17论文数:62被引数:920
K
Kanda Sangthongpitag
H 指数:20论文数:105被引数:1,375
V
Vishal Pendharkar
H 指数:16论文数:84被引数:1,480
C
C. S. Brian Chia
H 指数:20论文数:53被引数:1,283
L
Liu, Boping
H 指数:0论文数:15被引数:0
A
Alvin W. Hung
H 指数:19论文数:65被引数:1,972
F
Fui Mee Ng
H 指数:14论文数:60被引数:497
K
Kassoum Nacro
H 指数:21论文数:67被引数:1,804