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N

Nichole Helton

washington university
H指数:15
被引数:1,225

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荣誉奖项

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Recurrent Amplification of Chromosome 7 in Murine AML with Dnmt3aR878H and Npm1cA Mutations Identifies Gab2 As a Possible Therapeutic Target in AML

携带Dnmt3aR878H和Npm1cA突变的鼠类急性髓系白血病中染色体7的反复扩增，将Gab2确定为急性髓系白血病中可能的潜在治疗靶点。

BLOOD
IF23.1
2024-11-050
PRE
Kramer, Michael H.; Richardson, Stephanie N.; Li, Yang; Yin, Tiankai; Helton, Nichole; George, Daniel; Cai, Michelle; Ramakrishnan, Sai Mukund; Miller, Christopher A.; Ley, Timothy J.
PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self- renewal in mouse and human hematopoietic cells

PML::RARA和GATA2蛋白通过DNA模板相互作用，诱导小鼠和人类造血细胞的异常自我更新

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-04-220
OAAI
Katerndahl, Casey D. S.; Rogers, Olivia R. S.; Day, Ryan B.; Xu, Ziheng; Helton, Nichole M.; Ramakrishnan, Sai Mukund; Miller, Christopher A.; Ley, Timothy J.
Genomic landscape of TP53-mutated myeloid malignancies
BLOOD ADVANCES
IF7.1
2023-08-1113
OAAI
Abel, Haley J.; Oetjen, Karolyn A.; Miller, Christopher A.; Ramakrishnan, Sai M.; Day, Ryan B.; Helton, Nichole M.; Fronick, Catrina C.; Fulton, Robert S.; Heath, Sharon E.; Tarnawsky, Stefan P.; Srivatsan, Sridhar Nonavinkere; Duncavage, Eric J.; Schroeder, Molly C.; Payton, Jacqueline E.; Spencer, David H.; Walter, Matthew J.; Westervelt, Peter; Dipersio, John F.; Ley, Timothy J.; Link, Daniel C.
Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-11-2929
OAAI
Ferraro, Francesca; Miller, Christopher A.; Christensen, Keegan A.; Helton, Nichole M.; O'Laughlin, Margaret; Fronick, Catrina C.; Fulton, Robert S.; Kohlschmidt, Jessica; Eisfeld, Ann-Kathrin; Bloomfield, Clara D.; Ramakrishnan, Sai Mukund; Day, Ryan B.; Wartman, Lukas D.; Uy, Geoffrey L.; Welch, John S.; Christopher, Matthew J.; Heath, Sharon E.; Baty, Jack D.; Schuelke, Matthew J.; Payton, Jacqueline E.; Spencer, David H.; Rettig, Michael P.; Link, Daniel C.; Walter, Matthew J.; Westervelt, Peter; DiPersio, John F.; Ley, Timothy J.
Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome
NATURE COMMUNICATIONS
IF15.7
2021-07-2730
OAAI
Smith, Amanda M.; LaValle, Taylor A.; Shinawi, Marwan; Ramakrishnan, Sai M.; Abel, Haley J.; Hill, Cheryl A.; Kirkland, Nicole M.; Rettig, Michael P.; Helton, Nichole M.; Heath, Sharon E.; Ferraro, Francesca; Chen, David Y.; Adak, Sangeeta; Semenkovich, Clay F.; Christian, Diana L.; Martin, Jenna R.; Gabel, Harrison W.; Miller, Christopher A.; Ley, Timothy J.
Remethylation of Dnmt3a-/- hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-01-2926
OAAI
Ketkar, Shamika; Verdoni, Angela M.; Smith, Amanda M.; Bangert, Celia V.; Leight, Elizabeth R.; Chen, David Y.; Brune, Meryl K.; Helton, Nichole M.; Hoock, Mieke; George, Daniel R.; Fronick, Catrina; Fulton, Robert S.; Ramakrishnan, Sai Mukund; Chang, Gue Su; Petti, Allegra A.; Spencer, David H.; Miller, Christopher A.; Ley, Timothy J.
Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential
NATURE COMMUNICATIONS
IF15.7
2018-01-31155
OAAI
Wong, Terrence N.; Miller, Christopher A.; Jotte, Matthew R. M.; Bagegni, Nusayba; Baty, Jack D.; Schmidt, Amy P.; Cashen, Amanda F.; Duncavage, Eric J.; Helton, Nichole M.; Fiala, Mark; Fulton, Robert S.; Heath, Sharon E.; Janke, Megan; Luber, Kierstin; Westervelt, Peter; Vij, Ravi; DiPersio, John F.; Welch, John S.; Graubert, Timothy A.; Walter, Matthew J.; Ley, Timothy J.; Link, Daniel C.

研究方向

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T
Timothy J. Ley
H 指数:116论文数:538被引数:8.7万
C
Christopher A. Miller
H 指数:96论文数:552被引数:7.9万
S
Sai Mukund Ramakrishnan
H 指数:13论文数:67被引数:986
R
Robert S. Fulton
H 指数:154论文数:584被引数:21.6万
D
David H. Spencer
H 指数:35论文数:210被引数:1.2万
D
Daniel C. Link
H 指数:86论文数:815被引数:3.4万
C
Catrina C. Fronick
H 指数:95论文数:338被引数:9.0万
A
Amanda M. Smith
H 指数:12论文数:44被引数:726
S
Sharon E. Heath
H 指数:56论文数:180被引数:5.0万
J
John F. DiPersio
H 指数:126论文数:1,370被引数:9.5万