Michael H.G. Kubbutat - Publications, H-index & Citations

Michael H.G. Kubbutat

peking university

33H指数

114论文数

7.8K被引数

收录论文 49

发表时间

Relevance of substrate selection for the results of biochemical WEE1 in-vitro kinase activity inhibition assays

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Mueller, Daniel G.; Gericke, Andreas; Totzke, Frank; Heidemann-Dinger, Carolin; Ketterer, Constance; Kraemer, Diane; Weber, Thomas; Kubbutat, Michael H.

Identification of CDK15 activating cyclins by a recombinant co-expression approach

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Mueller, Daniel; Ketterer, Constance; Kraemer, Diane; Heidemann-Dinger, Carolin; Pilgermayer, Lena; Weber, Thomas; Gericke, Andreas; Totzke, Frank; Kubbutat, Michael H.

Proteolytic cleavage of human p53 by calpain: A potential regulator of protein stability

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

291

OAAI

Kubbutat, MHG; Vousden, KH

Regulation of Mdm2-directed degradation by the C terminus of p53

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

198

OAAI

Kubbutat, MHG; Ludwig, RL; Ashcroft, M; Vousden, KH

7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-ones Designed by a Cut and Glue Strategy Are Dual Aurora A/VEGF-R Kinase Inhibitors 通过切割和胶水策略设计的7-(2-苯胺嘧啶-4-基)-1-苯并氮杂卓-2-酮是双重极光a/vegf-r激酶抑制剂

MOLECULES

IF4.6

2021-03-14

OAAI

Karatas, Mehmet; Chaikuad, Apirat; Berger, Bianca; Kubbutat, Michael H. G.; Totzke, Frank; Knapp, Stefan; Kunick, Conrad

Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model

SCIENTIFIC REPORTS

IF3.9

2019-03-21

OAAI

Civit, Laia; Theodorou, Ioanna; Frey, Franziska; Weber, Holger; Lingnau, Andreas; Groeber, Carsten; Blank, Michael; Dambrune, Chloe; Stunden, James; Beyer, Marc; Schultze, Joachim; Latz, Eicke; Duconge, Frederic; Kubbutat, Michael H. G.; Mayer, Guenter

IC50 profiling against 320 protein kinases: Improving the accuracy of kinase inhibitor selectivity testing

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Mueller, Daniel; Totzke, Frank; Weber, Thomas; Pathe, Marcel; Schaechtele, Christoph; Kubbutat, Michael H.

Exploring the functions of TAM kinases: assay development and characterization of potential therapeutics

MOLECULAR CANCER THERAPEUTICS

IF5.5

2018-01-01

PREAI

Chakrabarti, Alokta; Feger, Daniel; Totzke, Frank; Umber, Sarah; Stus, Orysya; Birkle, Marianne; Siedentopf, Oliver; Pathe, Marcel; Weber, Thomas; Kubbutat, Michael H. G.; Ehlert, Jan E.

A biochemical approach to discriminate between ATP-competitive and non-ATP competitive protein kinase inhibitors

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Mueller, Daniel; Totzke, Frank; Weber, Thomas; Heidemann-Dinger, Carolin; Ketterer, Constance; Kramer, Diane; Pathe, Marcel; Kubbutat, Michael H.

Cytotoxic effects of the anthraquinone derivatives 1'-deoxyrhodoptilometrin and (S)-(-)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp.

ARCHIVES OF TOXICOLOGY

IF6.9

2016-07-29

PREAI

Waetjen, Wim; Ebada, Sherif S.; Bergermann, Anja; Chovolou, Yvonni; Totzke, Frank; Kubbutat, Michael H. G.; Lin, Wenhan; Proksch, Peter

Characterization of CDK inhibitors in a biochemical assay using a comprehensive panel of human CDK-cyclin complexes

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Mueller, Daniel; Totzke, Frank; Weber, Thomas; Beisenherz-Huss, Christian; Kraemer, Diane; Heidemann-Dinger, Carolin; Ketterer, Constance; Eckert, Chris; Kubbutat, Michael H. G.

Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-04-01

OAAI

Shchekotikhin, Andrey E.; Dezhenkova, Lyubov G.; Tsvetkov, Vladimir B.; Luzikov, Yuri N.; Volodina, Yulia L.; Tatarskiy, Victor V., Jr.; Kalinina, Anastasia A.; Treshalin, Michael I.; Treshalina, Helen M.; Romanenko, Vladimir I.; Kaluzhny, Dmitry N.; Kubbutat, Michael; Schols, Dominique; Pommier, Yves; Shtil, Alexander A.; Preobrazhenskaya, Maria N.

A comprehensive screen for protein kinases involved in histone phosphorylation using a biochemical in-vitro approach

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Mueller, Daniel; Totzke, Frank; Ketterer, Constance; Beisenherz-Huss, Christian; Kraemer, Diane; Weber, Thomas; Heidemann-Dinger, Carolin; Kubbutat, Michael H. G.

Studies on glycoprotein expression differences between MCF-7 and MCF-7-Z

EUROPEAN JOURNAL OF CANCER

IF7.1

2014-11-01

PREAI

Ner-Kluza, J.; Drabik, A.; Kubbutat, M.; Lingnau, A.; Silberring, J.

Biomarker discovery and validation for assessing the response to cMet inhibition and functional inactivation

EUROPEAN JOURNAL OF CANCER

IF7.1

2014-11-01

PREAI

Jung, S.; Selzer, S.; Loessner, C.; Kuhn, K.; Fiedler, U.; Klotzbuecher, A.; Zucht, H. D.; Koncarevic, S.; Prinz, T.; Hertfelder, D.; Boehme, K. A.; Volkmer, H.; Kubbutat, M. H. G.; Budde, P.; Pike, I.

Development of a non-radioactive method to determine Protein-Methyl-Transferase activity in-vitro

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Mueller, Daniel; Beisenherz-Huss, Christian; Heidemann-Dinger, Carolin; Ketterer, Constance; Kraemer, Diane; Kubbutat, Michael H. G.

Analysis of the impact of compounds derived from marine organisms on 3D co-spheroids generated from multiple myeloma cells and stromal cell types

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Ganesan, Jayanthi; Weber, Holger; Umber, Sarah; Siedentopf, Oliver; Feger, Daniel; Garcia-Fernandez, Luis F.; Aracil Avila, Miguel; Kubbutat, Michael H. G.; Ehlert, Jan E.

Development of First Lead Structures for Phosphoinositide 3-Kinase-C27γ Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-07-14

PREAI

Freitag, Anne; Prajwal, Prajwal; Shymanets, Aliaksei; Harteneck, Christian; Nuernberg, Bernd; Schaechtele, Christoph; Kubbutat, Michael; Totzke, Frank; Laufer, Stefan A.

Cytotoxic and Protein Kinase Inhibiting Nakijiquinones and Nakijiquinols from the Sponge Dactylospongia metachromia

JOURNAL OF NATURAL PRODUCTS

IF3.6

2014-01-30

PREAI

Daletos, Georgios; de Voogd, Nicole J.; Mueller, Werner E. G.; Wray, Victor; Lin, WenHan; Feger, Daniel; Kubbutat, Michael; Aly, Amal H.; Proksch, Peter

Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-01-01

129

PREAI

de Castro Barbosa, Maria Leticia; Lima, Lidia Moreira; Tesch, Roberta; Sant'Anna, Carlos Mauricio R.; Totzke, Frank; Kubbutat, Michael H. G.; Schaechtele, Christoph; Laufer, Stefan A.; Barreiro, Eliezer J.

研究方向