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收藏Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy
Kelly, Priscilla N.; Romero, Donna L.; Yang, Yibin; Shaffer, Arthur L., III; Chaudhary, Divya; Robinson, Shaughnessy; Miao, Wenyan; Rui, Lixin; Westlin, William F.; Kapeller, Rosana; Staudt, Louis M.
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收藏Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma
Krane, Carissa M.; Deng, Bijia; Mutyam, Venkateshwar; McDonald, Casey A.; Pazdziorko, Stephen; Mason, Lawrence; Goldman, Samuel; Kasaian, Marion; Chaudhary, Divya; Williams, Cara; Ho, Melisa W. Y.
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收藏Identification, characterization and initial hit-to-lead optimization of a series of 4-arylamino-3-pyridinecarbonitrile as protein kinase C theta (PKCθ) inhibitors
Cole, Derek C.; Asselin, Magda; Brennan, Agnes; Czerwinski, Robert; Ellingboe, John W.; Fitz, Lori; Greco, Rita; Huang, Xinyi; Joseph-McCarthy, Diane; Kelly, Michael F.; Kirisits, Matthew; Lee, Julie; Li, Yuanhong; Morgan, Paul; Stock, Joseph R.; Tsao, Desiree H. H.; Wissner, Allan; Yang, Xiaoke; Chaudhary, Divya
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收藏Catalytic domain crystal structure of protein kinase C-θ (PKC θ)
Xu, ZB; Chaudhary, D; Olland, S; Wolfrom, S; Czerwinski, R; Malakian, K; Lin, L; Stahl, ML; McCarthy, DJ; Benander, C; Fitz, L; Greco, R; Somers, WS; Mosyak, L
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收藏PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθPD-1抑制T细胞受体诱导的ZAP70/CD3ζ 信号小体磷酸化和pkc θ 的下游信号传导
Sheppard, KA; Fitz, LJ; Lee, JM; Benander, C; George, JA; Wooters, J; Qiu, YC; Jussif, JM; Carter, LL; Wood, CR; Chaudhary, D
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收藏PD-L2 is a second ligand for PD-I and inhibits T cell activationPD-L2是pd-i的第二配体并抑制T细胞活化
Latchman, Y; Wood, CR; Chernova, T; Chaudhary, D; Borde, M; Chernova, I; Iwai, Y; Long, AJ; Brown, JA; Nunes, R; Greenfield, EA; Bourque, K; Boussiotis, VA; Carter, LL; Carreno, BM; Malenkovich, N; Nishimura, H; Okazaki, T; Honjo, T; Sharpe, AH; Freeman, GJ
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