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Rare earth Eu doped WO3 film prepared by magnetron sputtering for high response UV-Vis-NIR fast photodetector Chen, Ye; Qi, Dongli; Shen, Longhai; Kuang, Ye; Song, Jianyu; Zhu, Xiaotian; Ji, Qiqi; Zhu, Tingting; Li, Ziyuan; Han, Mengyao; Xu, Junhao; Li, Yuhao 分享 收藏
Photoelectric characteristic of single-phase InxGa1-xN films with tunable bandgap through RF magnetron sputtering (vol 59, pg 21828, 2024) Li, Ziyuan; Shen, Longhai; Zhou, Ouxiang; Zhu, Xiaotian; Zhang, Yu; Wang, Quhui; Qi, Dongli; Zhang, Xinglai; Han, Mengyao; Xu, Junhao; Chen, Ye; Li, Yuhao 分享 收藏
Photoelectric characteristic of single-phase InxGa1-xN films with tunable bandgap through RF magnetron sputtering Li, Ziyuan; Shen, Longhai; Zhou, Ouxiang; Zhu, Xiaotian; Zhang, Yu; Wang, Quhui; Qi, Dongli; Zhang, Xinglai; Han, Mengyao; Xu, Junhao; Chen, Ye; Li, Yuhao 分享 收藏
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Discovery of RGT-018: A potent, selective and orally bioavailable SOS1 inhibitor for mutant KRAS-driven cancers Xiao, Fei; Wang, Kailiang; Wang, Xinjuan; Li, Huijuan; Hu, Zhilong; Huang, Wei; Ren, Xiaoming; Feng, Teng; Yao, Lili; Lin, Jing; Li, Chunlai; Mei, Liufeng; Zhang, Zhuanzhuan; Liu, Yangyang; Chen, Xi; Zhu, Xiaotian; Zhong, Wenge; Xie, Zhi 分享 收藏
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Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non-Small Cell Lung Cancer Gonzalvez, Francois; Vincent, Sylvie; Baker, Theresa E.; Gould, Alexandra E.; Li, Shuai; Wardwell, Scott D.; Nadworny, Sara; Ning, Yaoyu; Zhang, Sen; Huang, Wei-Sheng; Hu, Yongbo; Li, Feng; Greenfield, Matthew T.; Zech, Stephan G.; Das, Biplab; Narasimhan, Narayana, I; Clackson, Tim; Dalgarno, David; Shakespeare, William C.; Fitzgerald, Michael; Chouitar, Johara; Griffin, Robert J.; Liu, Shengwu; Wong, Kwok-Kin; Zhu, Xiaotian; Rivera, Victor M. 分享 收藏
AP32788, a potent, selective inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, in preclinical models Gonzalvez, Francois; Zhu, Xiaotian; Huang, Wei-Sheng; Baker, Theresa E.; Ning, Yaoyu; Wardwell, Scott D.; Nadworny, Sara; Zhang, Sen; Das, Biplab; Gong, Yongjin; Greenfield, Matthew T.; Jang, Hyun G.; Kohlmann, Anna; Li, Feng; Taslimi, Paul M.; Tugnait, Meera; Xu, Yongjin; Ye, Emily Y.; Youngsaye, Willmen W.; Zech, Stephan G.; Zhang, Yun; Zhou, Tianjun; Narasimhan, Narayana I.; Dalgarno, David C.; Shakespeare, William C.; Rivera, Victor M. 分享 收藏
Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase 布格替尼 (AP26113) 的发现，一种含氧化膦的、有效的、口服活性的间变性淋巴瘤激酶抑制剂 Huang, Wei-Sheng; Liu, Shuangying; Zou, Dong; Thomas, Mathew; Wang, Yihan; Zhou, Tianjun; Romero, Jan; Kohlmann, Anna; Li, Feng; Qi, Jiwei; Cai, Lisi; Dwight, Timothy A.; Xu, Yongjin; Xu, Rongsong; Dodd, Rory; Toms, Angela; Parillon, Lois; Lu, Xiaohui; Anjum, Rana; Zhang, Sen; Wang, Frank; Keats, Jeffrey; Wardwell, Scott D.; Ning, Yaoyu; Xu, Qihong; Moran, Lauren E.; Mohemmad, Qurish K.; Jang, Hyun Gyung; Clackson, Tim; Narasimhan, Narayana I.; Rivera, Victor M.; Zhu, Xiaotian; Dalgarno, David; Shakespeare, William C. 分享 收藏
Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery Zech, Stephan G.; Kohlmann, Anna; Zhou, Tianjun; Li, Feng; Squillace, Rachel M.; Parillon, Lois E.; Greenfield, Matthew T.; Miller, David P.; Qi, Jiwei; Thomas, R. Mathew; Wang, Yihan; Xu, Yongjin; Miret, Juan J.; Shakespeare, William C.; Zhu, Xiaotian; Dalgarno, David C. 分享 收藏
Discovery of AP26113, a potent, orally active inhibitor of anaplastic lymphoma kinase and clinically relevant mutants Huang, Wei-Sheng; Li, Feng; Cai, Lisi; Xu, Yongjin; Zhang, Sen; Wardwell, Scott D.; Ning, Yaoyu; Kohlmann, Anna; Zhou, Tianjun; Ye, Emily Y.; Zhu, Xiaotian; Narasimhan, Narayana I.; Clackson, Tim; Rivera, Victor M.; Dalgarno, David; Shakespeare, William C. 分享 收藏
Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors Kohlmann, Anna; Zech, Stephan G.; Li, Feng; Zhou, Tianjun; Squillace, Rachel M.; Commodore, Lois; Greenfield, Matthew T.; Lu, Xiaohui; Miller, David P.; Huang, Wei-Sheng; Qi, Jiwei; Thomas, R. Mathew; Wang, Yihan; Zhang, Sen; Dodd, Rory; Liu, Shuangying; Xu, Rongsong; Xu, Yongjin; Miret, Juan J.; Rivera, Victor; Clackson, Tim; Shakespeare, William C.; Zhu, Xiaotian; Dalgarno, David C. 分享 收藏
Small molecule inhibitors of choline kinase lead to reduced phosphocholine levels and induction of apoptosis in cancer cells Squillace, Rachel M.; Zech, Stephan; Li, Feng; Kohlmann, Anna; Miller, David; Greenfield, Matthew; Ning, Yaoyu; Commodore, Lois; Miret, Juan; Wang, Frank; Zhou, Tianjun; Wang, Yihan; Thomas, Matthew; Qi, Jiwei; Xu, Yongjin; Rivera, Victor; Clackson, Tim; Zhu, Xiaotian; Shakespeare, William; Delgarno, David 分享 收藏
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Crizotinib-Resistant Mutants of EML4-ALK Identified Through an Accelerated Mutagenesis Screen Zhang, Sen; Wang, Frank; Keats, Jeffrey; Zhu, Xiaotian; Ning, Yaoyu; Wardwell, Scott D.; Moran, Lauren; Mohemmad, Qurish K.; Anjum, Rana; Wang, Yihan; Narasimhan, Narayana I.; Dalgarno, David; Shakespeare, William C.; Miret, Juan J.; Clackson, Tim; Rivera, Victor M. 分享 收藏
Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance Zhou, Tianjun; Commodore, Lois; Huang, Wei-Sheng; Wang, Yihan; Thomas, Mathew; Keats, Jeff; Xu, Qihong; Rivera, Victor M.; Shakespeare, William C.; Clackson, Tim; Dalgarno, David C.; Zhu, Xiaotian 分享 收藏
Discovery of 3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a Potent, Orally Active Pan-Inhibitor of Breakpoint Cluster Region-Abelson (BCR-ABL) Kinase Including the T315I Gatekeeper Mutant Huang, Wei-Sheng; Metcalf, Chester A.; Sundaramoorthi, Raji; Wang, Yihan; Zou, Dong; Thomas, R. Mathew; Zhu, Xiaotian; Cai, Lisi; Wen, David; Liu, Shuangying; Romero, Jan; Qi, Jiwei; Chen, Ingrid; Banda, Geetha; Lentini, Scott P.; Das, Sasmita; Xu, Qihong; Keats, Jeff; Wang, Frank; Wardwell, Scott; Ning, Yaoyu; Snodgrass, Joseph T.; Broudy, Marc I.; Russian, Karin; Zhou, Tianjun; Commodore, Lois; Narasimhan, Narayana I.; Mohemmad, Qurish K.; Iuliucci, John; Rivera, Victor M.; Dalgarno, David C.; Sawyer, Tomi K.; Clackson, Tim; Shakespeare, William C. 分享 收藏
Structural analysis of the inhibitory mechanism of AP24534, a pan-BCR-ABL inhibitor overriding the T315I gatekeeper mutation Zhu, Xiaotian; Zhou, Tianjun; Shakespeare, William C.; Huang, Wei-Sheng; Commodore, Lois; Metcalf, Chester A.; Wang, Yihan; Thomas, Mathew; Sundaramoorthi, Raji; Zou, Dong; Sawyer, Tomi K.; Clackson, Tim; Dalgarno, David C. 分享 收藏
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