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Stewart Shuman

memorial sloan kettering cancer center

80H指数
588论文数
2.6W被引数
收录论文 337
发表时间
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How interdiction of inositol pyrophosphate catabolism perturbs the fission yeast response to phosphate starvation抑制肌醇焦磷酸盐分解代谢干扰裂殖酵母对磷酸盐饥饿的响应
errNucleic Acids Research
IF13.1
err2026-04-25
err0
errOAAI
errJill Babor; Ana M Sanchez; Isabel Prucker; Henning J Jessen; Beate Schwer; Stewart Shuman; null
err分享
err收藏
Structure of an initiation complex of mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals local melting that engages the 3′ tracking strand at the ratchet pawl of the helicase motor分枝杆菌解旋酶-核酸酶AdnAB在 blunt double-strand break 处起始复合物的结构揭示局部熔解，其涉及解旋酶马达的棘爪棘轮处的3′追踪链
errNucleic Acids Research
IF13.1
err2026-04-13
err0
PREAI
errWarren, Garrett M.; de la Cruz, M. Jason; Goldgur, Yehuda; Shuman, Stewart
err分享
err收藏
Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast转运蛋白驱动的甘油磷胆碱（GPC）毒性从裂殖酵母到出芽酵母得以保留：肌醇焦磷酸盐和Gde1调控在裂殖酵母中的作用
errBiomolecules
IF4.8
err2026-02-16
err0
errOAAI
errHrach, Victoria Lee; Schwer, Beate; Vitek, Lane; Borowicz, Michael; Innokentev, Aleksei; Sanchez, Ana M.; Singer, Justin R.; Shuman, Stewart; Patton-Vogt, Jana
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Fission yeast Tpt1 is composed of tandem RNA 2′-phosphotransferase and Yae1 domains, both of which are essential for viability裂殖酵母Tpt1由串联的RNA 2′-磷酸转移酶和Yae1结构域组成，两者对细胞存活均至关重要
errRNA
IF5
err2026-02-01
err0
PREAI
errSarkar, Apurba; Schwer, Beate; Shuman, Stewart
err分享
err收藏
Desthiobiotin (DTB)-modified and TAMRA-modified 2OMeNAD+ are RNA 2′-phosphotransferase (Tpt1) poisons that enable affinity-tagging and fluorescence-tagging of internal RNA 2′-phosphate groupsDesthiobiotin (DTB)修饰和TAMRA修饰的2OMeNAD+是RNA 2′-磷酸转移酶(Tpt1)的抑制剂，能够实现内部RNA 2′-磷酸基团的亲和标签化和荧光标签化。
errRNA
IF5
err2025-12-01
err0
PREAI
errKasprzyk, Renata; Ghosh, Shreya; Shuman, Stewart
err分享
err收藏
Genetic suppression of precocious transcription termination identifies mutations in essential subunits of the fission yeast cleavage and polyadenylation machinery
errRNA
IF5
err2025-11-01
err0
PREAI
errInnokentev, Aleksei; Sanchez, Ana M.; Bednor, Lauren; Babor, Jill; Schwer, Beate; Shuman, Stewart
err分享
err收藏
Structural basis for sensitivity and acquired resistance of fungal cap guanine-N7 methyltransferases to the antifungal antibiotic sinefungin真菌帽状鸟嘌呤-N7甲基转移酶对真菌抗生素sinefungin的敏感性及获得性耐药性的结构基础
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-08-12
err1
errOAAI
errNilson, Daniel J.; Schwer, Beate; Almo, Steven C.; Shuman, Stewart; Ghosh, Agnidipta
err分享
err收藏
Tandem inactivation of inositol pyrophosphatases Asp1, Siw14, and Aps1 illuminates functional redundancies in inositol pyrophosphate catabolism in fission yeast串联失活inositol pyrophosphatases Asp1、Siw14和Aps1揭示了裂殖酵母中肌醇焦磷酸分解代谢的功能冗余性
errMBIO
IF4.7
err2025-05-14
err0
errOAAI
errSchwer, Beate; Prucker, Isabel; Sanchez, Ana M.; Babor, Jill; Jessen, Henning J.; Shuman, Stewart
err分享
err收藏
In vivo nucleotide excision repair by mycobacterial UvrD1 requires ATP hydrolysis but does not depend on cysteine disulfide-mediated dimerization and DNA unwinding分枝杆菌UvrD1的体内核苷酸切除修复需要ATP水解，但不依赖于半胱氨酸二硫化物介导的二聚和DNA解旋
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-04-07
err0
PREAI
errWarren, Garrett M.; Shuman, Stewart
err分享
err收藏
Fission yeast metabolome dynamics during phosphate starvation and replenishment
errMBIO
IF4.7
err2025-02-25
err0
errOAAI
errSanchez, Ana M.; Kyaw, Aye K.; Violante, Sara Nunes; Garg, Angad; Cross, Justin R.; Shuman, Stewart
err分享
err收藏
Efn1 and Efn2 are extracellular 5'-nucleotidases induced during the fission yeast response to phosphate starvation
errMBIO
IF4.7
err2025-01-08
err0
errOAAI
errInnokentev, Aleksei; Sanchez, Ana M.; Monetti, Mara; Schwer, Beate; Shuman, Stewart
err分享
err收藏
Chemical synthesis of 2OMeNAD+ and its deployment as an RNA 2′-phosphotransferase (Tpt1) 'poison' that traps the enzyme on its abortive RNA-2′-PO4-(ADP-2OMe-ribose) reaction intermediate
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-08-20
err0
errOAAI
errArnold, Jakob; Ghosh, Shreya; Kasprzyk, Renata; Brakonier, Marcel; Hanna, Markus; Marx, Andreas; Shuman, Stewart
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Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase
errMBIO
IF4.7
err2024-08-14
err1
errOAAI
errGhosh, Shreya; Sanchez, Ana M.; Schwer, Beate; Prucker, Isabel; Jork, Nikolaus; Jessen, Henning J.; Shuman, Stewart
err分享
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Structure and in vivo psoralen DNA crosslink repair activity of mycobacterial Nei2
errMBIO
IF4.7
err2024-08-14
err0
errOAAI
errWarren, Garrett M.; Shuman, Stewart
err分享
err收藏
Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1
errMBIO
IF4.7
err2024-07-17
err0
errOAAI
errSchwer, Beate; Innokentev, Aleksei; Sanchez, Ana M.; Garg, Angad; Shuman, Stewart
err分享
err收藏
Kinetic and structural insights into the requirement of fungal tRNA ligase for a 2′-phosphate end
errRNA
IF5
err2024-07-16
err0
PREAI
errGhosh, Shreya; Shuman, Stewart
err分享
err收藏
Deletions initiated by the vaccinia virus TopIB protein in yeast
errDNA REPAIR
IF2.7
err2024-05-01
err0
PREAI
errCho, Jang Eun; Shaltz, Samantha; Yakovleva, Lyudmila; Shuman, Stewart; Jinks-Robertson, Sue
err分享
err收藏
Enhanced transport of glycerophosphocholine, a common lipid metabolite, inhibits growth of Saccharomyces cerevisiae and Schizosaccharomyces pombe
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errSinger, Justin; Hrach, Victoria; Schwer, Beate; Shuman, Stewart; Patton-Vogt, Jana
err分享
err收藏
Factors governing the transcriptome changes and chronological lifespan of fission yeast during phosphate starvation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err4
errOAAI
errGarg, Angad; Sanchez, Ana M.; Schwer, Beate; Shuman, Stewart
err分享
err收藏
Genetic suppressor screen identifies Tgp1 (glycerophosphocholine transporter), Kcs1 (IP6 kinase), and Plc1 (phospholipase C) as determinants of inositol pyrophosphate toxicosis in fission yeast
errMBIO
IF4.7
err2024-02-14
err5
errOAAI
errBednor, Lauren; Sanchez, Ana M.; Garg, Angad; Shuman, Stewart; Schwer, Beate
err分享
err收藏

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