Michael L. Cleary - Publications, H-index & Citations

Michael L. Cleary

Genentech

92H指数

266论文数

3.0W被引数

收录论文 68

发表时间

Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL

BLOOD ADVANCES

IF7.1

2024-05-31

OAAI

Gentile, Gaia; Poggio, Teresa; Catalano, Antonella; Voutilainen, Minna; Lahnalampi, Mari; Andrade-Martinez, Marta; Ma, Tobias; Sankowski, Roman; Goncharenko, Lina; Tholen, Stefan; Han, Kyuho; Morgens, David W.; Prinz, Marco; Luebbert, Michael; Engel, Sophia; Hartmann, Tanja Nicole; Cario, Gunnar; Schrappe, Martin; Lenk, Lennart; Stanulla, Martin; Duyster, Justus; Bronsert, Peter; Bassik, Michael C.; Cleary, Michael L.; Schilling, Oliver; Heinaniemi, Merja; Duque-Afonso, Jesus

Genome editing-induced t(4;11) chromosomal translocations model B cell precursor acute lymphoblastic leukemias with KMT2A-AFF1 fusion

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-01-02

OAAI

Pan, Feng; Sarno, Jolanda; Jeong, Johan; Yang, Xin; Jager, Astraea; Gruber, Tanja A.; Davis, Kara L.; Cleary, Michael L.

Age and ligand specificity influence the outcome of pathogen engagement on preleukemic and leukemic B-cell precursor populations

BLOOD ADVANCES

IF7.1

2023-11-20

OAAI

Atre, Tanmaya; Farrokhi, Ali; Jo, Sumin; Salitra, Samuel; Duque-Afonso, Jesus; Cleary, Michael L.; Rolf, Nina; Reid, Gregor S. D.

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants( vol 28 , pg 1083 , 2022)

NATURE MEDICINE

IF50

2023-11-09

OAAI

Welch, Nicole L.; Zhu, Meilin; Hua, Catherine; Weller, Juliane; Mirhashemi, Marzieh Ezzaty; Nguyen, Tien G.; Mantena, Sreekar; Bauer, Matthew R.; Shaw, Bennett M.; Ackerman, Cheri M.; Thakku, Sri Gowtham; Tse, Megan W.; Kehe, Jared; Uwera, Marie-Martine; Eversley, Jacqueline S.; Bielwaski, Derek A.; McGrath, Graham; Braidt, Joseph; Johnson, Jeremy; Cerrato, Felecia; Moreno, Gage K.; Krasilnikova, Lydia A.; Petros, Brittany A.; Gionet, Gabrielle L.; King, Ewa; Huard, Richard C.; Jalbert, Samantha K.; Cleary, Michael L.; Fitzgerald, Nicholas A.; Gabriel, Stacey B.; Gallagher, Glen R.; Smole, Sandra C.; Madoff, Lawrence C.; Brown, Catherine M.; Keller, Matthew W.; Wilson, Malania M.; Kirby, Marie K.; Barnes, John R.; Park, Daniel J.; Siddle, Katherine J.; Happi, Christian T.; Hung, Deborah T.; Springer, Michael; Macinnis, Bronwyn L.; Lemieux, Jacob E.; Rosenberg, Eric; Branda, John A.; Blainey, Paul C.; Sabeti, Pardis C.; Myhrvold, Cameron

Enhancer remodeling drives MLL oncogene-dependent transcriptional dysregulation in leukemia stem cells

BLOOD ADVANCES

IF7.1

2023-06-02

OAAI

Pan, Feng; Iwasaki, Masayuki; Wu, Wenqi; Jiang, Yanan; Yang, Xin; Zhu, Li; Zhao, Zhigang; Cleary, Michael L.

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

249

OAAI

Chang, CP; Jacobs, Y; Nakamura, T; Jenkins, NA; Copeland, NG; Cleary, ML

The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

OAAI

Chang, CP; DeVivo, I; Cleary, ML

The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

255

OAAI

Slany, RK; Lavau, C; Cleary, ML

Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9 果蝇Su(var)3-9的哺乳动物直系同源物SUV39H1对转录沉默和生长控制的Set结构域依赖性调控

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

111

OAAI

Firestein, R; Cui, XM; Huie, P; Cleary, ML

Trimeric association of hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

237

OAAI

Jacobs, Y; Schnabel, CA; Cleary, ML

Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

167

OAAI

Ayton, PM; Chen, EH; Cleary, ML

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Nie, ZQ; Yan, ZJ; Chen, EH; Sechi, S; Ling, C; Zhou, SL; Xue, YT; Yang, DF; Murray, D; Kanakubo, E; Cleary, ML; Wang, WD

The TALE homeodomain protein pbx2 is not essential for development and long-term survival

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Selleri, L; DiMartino, J; van Deursen, J; Brendolan, A; Sanyal, M; Boon, E; Capellini, T; Smith, KS; Rhee, J; Pöpperl, H; Grosveld, G; Cleary, ML

MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

103

OAAI

So, CW; Cleary, ML

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

662

OAAI

Yokoyama, A; Wang, Z; Wysocka, J; Sanyal, M; Aufiero, DJ; Kitabayashi, I; Herr, W; Cleary, ML

Transformation of bone marrow B-cell progenitors by E2A-HLF requires coexpression of BCL-2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Smith, KS; Rhee, JW; Cleary, ML

A Novel Gli3 Enhancer Controls the Gli3 Spatiotemporal Expression Pattern through a TALE Homeodomain Protein Binding Site 一种新的Gli3增强子通过TALE同源域蛋白结合位点控制Gli3时空表达模式

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Coy, Sarah; Caamano, Jorge H.; Carvajal, Jaime; Cleary, Michael L.; Borycki, Anne-Gaelle

Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia

CANCER GENE THERAPY

IF5

2022-07-06

OAAI

Grueninger, Patricia K.; Uhl, Franziska; Herzog, Heike; Gentile, Gaia; Andrade-Martinez, Marta; Schmidt, Tobias; Han, Kyuho; Morgens, David W.; Bassik, Michael C.; Cleary, Michael L.; Gorka, Oliver; Zeiser, Robert; Gross, Olaf; Duque-Afonso, Jesus

Early Introduction and Rise of the Omicron Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant in Highly Vaccinated University Populations

CLINICAL INFECTIOUS DISEASES

IF7.3

2022-07-01

OAAI

Petros, Brittany A.; Turcinovic, Jacquelyn; Welch, Nicole L.; White, Laura F.; Kolaczyk, Eric D.; Bauer, Matthew R.; Cleary, Michael; Dobbins, Sabrina T.; Doucette-Stamm, Lynn; Gore, Mitch; Nair, Parvathy; Nguyen, Tien G.; Rose, Scott; Taylor, Bradford P.; Tsang, Daniel; Wendlandt, Erik; Hope, Michele; Platt, Judy T.; Jacobson, Karen R.; Bouton, Tara; Yune, Seyho; Auclair, Jared R.; Landaverde, Lena; Klapperich, Catherine M.; Hamer, Davidson H.; Hanage, William P.; MacInnis, Bronwyn L.; Sabeti, Pardis C.; Connor, John H.; Springer, Michael

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

NATURE MEDICINE

IF50

2022-02-07

151

OAAI

Welch, Nicole L.; Zhu, Meilin; Hua, Catherine; Weller, Juliane; Mirhashemi, Marzieh Ezzaty; Nguyen, Tien G.; Mantena, Sreekar; Bauer, Matthew R.; Shaw, Bennett M.; Ackerman, Cheri M.; Thakku, Sri Gowtham; Tse, Megan W.; Kehe, Jared; Uwera, Marie-Martine; Eversley, Jacqueline S.; Bielwaski, Derek A.; McGrath, Graham; Braidt, Joseph; Johnson, Jeremy; Cerrato, Felecia; Moreno, Gage K.; Krasilnikova, Lydia A.; Petros, Brittany A.; Gionet, Gabrielle L.; King, Ewa; Huard, Richard C.; Jalbert, Samantha K.; Cleary, Michael L.; Fitzgerald, Nicholas A.; Gabriel, Stacey B.; Gallagher, Glen R.; Smole, Sandra C.; Madoff, Lawrence C.; Brown, Catherine M.; Keller, Matthew W.; Wilson, Malania M.; Kirby, Marie K.; Barnes, John R.; Park, Daniel J.; Siddle, Katherine J.; Happi, Christian T.; Hung, Deborah T.; Springer, Michael; MacInnis, Bronwyn L.; Lemieux, Jacob E.; Rosenberg, Eric; Branda, John A.; Blainey, Paul C.; Sabeti, Pardis C.; Myhrvold, Cameron

研究方向