Adam R. Brown - Publications, H-index & Citations

Adam R. Brown

Pfizer

22H指数

63论文数

3.7K被引数

收录论文 15

发表时间

Rapid Development and First GMP Manufacture of AMPKγ3 Activator PF-07293893

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2026-01-01

PREAI

Baer, Jocelyn L.; Brandt, Thomas A.; Brown, Adam R.; Curto, John M.; Ellinwood, Duncan C.; Hubbell, Aran K.; Liu, Yiyang; Murray, John; Reyes, Giselle P.; Scism, Robert; Tcyrulnikov, Sergei; Wang, Aining; Weinstein, Ethan; Weisenburger, Gerald A.; Vetelino, Michael G.

Synthesis of Nirmatrelvir: Development of an Efficient, Scalable Process to Generate the Western Fragment

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2023-11-25

OAAI

Algera, Russell F.; Allais, Christophe; Baldwin, Aaron F.; Becirovic, Husein; Bowles, Paul; Brown, Adam R.; Buske, Jamie M.; Clarke, Hugh J.; Do, Nga M.; Doyle, Kevin; Fifer, Jonathan; Gray, Kaitlyn; Happe, Alan; Hardink, Mark; Hubbell, Aran K.; James, Chintelle; Khadamkar, Hrushikesh P.; Magano, Javier; McInturff, Emma L.; Mustakis, Jason; Ozbuyukkaya, Gizem; Piper, Jared L.; Place, David W.; Ragan, John A.; Rauschenberger, Blake; Reyes, Giselle; Shehadeh, Rawan; Stanchina, Corey; Stanley, Michael; Weekly, R. Matthew; Weinstein, Ethan; Weisenburger, Gerald A.; Wood, Ethan; Yayla, Hatice G.; Yu, Shu

Synthesis of Nirmatrelvir: Development of Magnesium Sulfate-Mediated Aminolysis for the Manufacture of the Eastern Fragment

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2023-11-22

PREAI

Algera, Russell F.; Allais, Christophe; Becirovic, Husein; Brown, Adam R.; Chen, Bo; Clarke, Hugh J.; Concannon, Paul E.; Du, Yansheng; Georgian, William; Lee, Johnny W.; Lee, Taegyo; Magano, Javier; Mandry, Carlos Perez; Mehta, Ruchi; Mull, Eric; Pearson, Robert; Peng, Zhihui; Piper, Jared L.; Ragan, John A.; Reyes, Giselle; Shen, Haibo; Ward, Daniel W.; Weekly, R. Matthew; Weisenburger, Gerald A.; Xu, Pengcheng; Yayla, Hatice G.; Zhang, Mengtan

Quantum Gravity in the Lab. I. Teleportation by Size and Traversable Wormholes

PRX QUANTUM

IF11

2023-02-27

OAAI

Brown, Adam R.; Gharibyan, Hrant; Leichenauer, Stefan; Lin, Henry W.; Nezami, Sepehr; Salton, Grant; Susskind, Leonard; Swingle, Brian; Walter, Michael

Quantum Gravity in the Lab. II. Teleportation by Size and Traversable Wormholes

PRX QUANTUM

IF11

2023-02-27

OAAI

Nezami, Sepehr; Lin, Henry W.; Brown, Adam R.; Gharibyan, Hrant; Leichenauer, Stefan; Salton, Grant; Susskind, Leonard; Swingle, Brian; Walter, Michael

Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2023-02-03

PREAI

Allais, Christophe; Bernhardson, David; Brown, Adam R.; Chinigo, Gary M.; Desrosiers, Jean-Nicolas; DiRico, Kenneth J.; Hotham, Ian; Jones, Brian P.; Kulkarni, Samir A.; Lewis, Chad A.; Lira, Ricardo; Loach, Richard P.; Morse, Peter D.; Mousseau, James J.; Perry, Matthew A.; Peng, Zhihui; Place, David W.; Rane, Anil M.; Samp, Lacey; Singer, Robert A.; Wang, Zheng; Weisenburger, Gerald A.; Yayla, Hatice G.; Zanghi, Joseph M.

The smallest interacting universe

JOURNAL OF HIGH ENERGY PHYSICS

IF5.5

2023-01-16

OAAI

Zini, Modjtaba Shokrian; Brown, Adam R. R.; Freedman, Michael

A quantum complexity lower bound from differential geometry

NATURE PHYSICS

IF18.4

2023-01-09

OAAI

Brown, Adam R.

A radical chlorodifluoromethylation protocol for late-stage difluoromethylation and its application to an oncology candidate

CELL REPORTS PHYSICAL SCIENCE

IF7.3

2021-04-01

OAAI

Meng, Depei; Li, Lingchun; Brown, Adam; Desrosiers, Jean-Nicolas; Duan, Shengquan; Hayward, Cheryl M.; He, Zhengbiao; Hu, Jinbo; Makowski, Teresa; Maloney, Mark; Monfette, Sebastien; Perfect, Hahdi; Piper, Jared L.; Zhou, Min; Widlicka, Daniel W.

Playing Pool with |ψ⟩: from Bouncing Billiards to Quantum Search

QUANTUM

IF5.4

2020-11-02

OAAI

Brown, Adam R.

The Python's Lunch: geometric obstructions to decoding Hawking radiation 蟒蛇的午餐: 解码霍金辐射的几何障碍

JOURNAL OF HIGH ENERGY PHYSICS

IF5.5

2020-08-25

OAAI

Brown, Adam R.; Gharibyan, Hrant; Penington, Geoff; Susskind, Leonard

Continuous Process for Preparing the Difluoromethylating Reagent [(DMPU)2Zn(CF2H)2] and Improved Synthesis of the ICHF2 Precursor

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2020-05-05

PREAI

Monfette, Sebastien; Fang, Yuan-Qing; Bio, Matthew M.; Brown, Adam R.; Crouch, Ian T.; Desrosiers, Jean-Nicolas; Duan, Shengquan; Hawkins, Joel M.; Hayward, Cheryl M.; Peperni, Nikita; Rainville, Joseph P.

CAN WE MINE A BLACK HOLE?

SCIENTIFIC AMERICAN

IF3.1

2015-01-20

PREAI

Brown, Adam

Development of a Scalable Synthesis of a HPK1 Inhibitor Featuring a Direct α-Arylation of Boc-Protected N; N-Dimethylamine by Palladium-Mediated Negishi Cross-Coupling 一种HPK1抑制剂的规模化合成方法，该方法具有通过钯介导的Negishi交叉偶联直接进行Boc保护的N,N-二甲基胺的α-芳基化特征。

The Journal of Organic Chemistry

IF0

PREAI

Dahui Zhou; Matthew Del Bel; Thomas Knauber; Simon Berritt; John Braganza; Adam Brown; Anne-Marie Dechert Schmitt; Rebecca Gallego; Mingying He; Jennifer Lafontaine; Jean Matthews; Peter Morse; Sebastien Monfette; Neal Sach; Joseph Tucker; Lei Zhang; Ru Zhou; Pingyong Liao; Tongnan Liu; Fanxiu Meng; Qiming Mu; Bin Sun; Chaobo Wu; Xin Zhao; Sajiv Nair

Development of Scalable Synthesis of Chiral Sultam via a Chiral Phosphoric Acid-Promoted tert-Butyl Carbamate Deprotection–Resolution Sequence or Diastereoselective Hydrogenation 通过手性磷酸催化的叔丁基氨基甲酸酯脱保护-拆分序列或非对映选择性氢化法，实现手性硫内酰胺的可扩展合成

Organic Process Research & Development

IF3.5

PREAI

Caroline A. Blakemore; Adam R. Brown; Todd W. Butler; Christopher W. am Ende; Nahian Khan; Sarai Lara-Boykin; Bryan Li; Guochun Ma; Javier Magano; Subham Mahapatra; Peter D. Morse; Giselle P. Reyes; Colin Rose; Neal W. Sach; Liam S. Sharninghausen; Jared Van Haitsma; Pengzhi Wang; Daniel W. Widlicka; Zebediah C. Girvin

研究方向