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Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site-Specific Integration of CFTR and Mutation-Agnostic Disease Rescue Foley, Ruth A.; Ayoub, Paul G.; Sinha, Vrishti; Juett, Colin; Sanoyca, Alicia; Duggan, Emily C.; Lathrop, Lindsay E.; Bhatt, Priyanka; Coote, Kevin; Illek, Beate; Gomperts, Brigitte N.; Kohn, Donald B.; Jonas, Steven J. 分享 收藏
Protocol Protocol for constructing an accessible exposure chamber for in vitro and in vivo modeling of airway environmental exposures 方案 构建可访问暴露舱的方案,用于体外和体内气道环境暴露的建模 Durra, Abdo; Cherry, Caroline; Luo, Coline; Huo, Emily; Passamano, Isabella; Castillo, Kristen; Lund, Andrew J.; Choi, Woosuk; Sen, Chandani; Chandran, Rachana; Rickabaugh, Tammy M.; Gomperts, Brigitte N. 分享 收藏
Open Source Repurposing Reveals Broad-Spectrum Antiviral Activity of Diphenylureas Betz, Ulrich A. K.; Garces, Robert; Beier, Norbert; Lindemann, Sven; Wolff, Karen C.; Riva, Laura; Kirkpatrick, Melanie G.; Gebara-Lamb, Amal; Mcnamara, Case W.; Damoiseaux, Robert; Gomperts, Brigitte N.; Arumugaswami, Vaithilingaraja; Strand, Marten; Gwon, Yongdae; Elofsson, Mikael; Evander, Magnus 分享 收藏
Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2 针对SARS-CoV-2的中等通量药物筛选,对微尺度人近端气道上皮气液界面模型的优化 Sen, Chandani; Rickabaugh, Tammy M.; Jeyachandran, Arjit Vijey; Yuen, Constance; Ghannam, Maisam; Durra, Abdo; Aziz, Adam; Castillo, Kristen; Garcia, Gustavo; Purkayastha, Arunima; Han, Brandon; Boulton, Felix W.; Chekler, Eugene; Garces, Robert; Wolff, Karen C.; Riva, Laura; Kirkpatrick, Melanie G.; Gebara-Lamb, Amal; Mcnamara, Case W.; Betz, Ulrich A. K.; Arumugaswami, Vaithilingaraja; Damoiseaux, Robert; Gomperts, Brigitte N. 分享 收藏
Light- field tomographic fluorescence lifetime imaging microscopy 光场层析荧光寿命成像显微镜 Ma, Yayao; Park, Jongchan; Huang, Luzhe; Sen, Chandani; Burri, Samuel; Bruschini, Claudio; Yang, Xilin; Cui, Qi; Cameron, Robert B.; Fishbein, Gregory A.; Gomperts, Brigitte N.; Ozcan, Aydogan; Charbon, Edoardo; Gao, Liang 分享 收藏
Pulmonary Fibrosis Stakeholder Summit A Joint NHLBI, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report 肺纤维化利益相关者峰会联合NHLBI,三湖基金会和肺纤维化基金会研讨会报告 Montesi, Sydney B.; Gomez, Christian R.; Beers, Michael; Brown, Robert; Chattopadhyay, Ishanu; Flaherty, Kevin R.; Garcia, Christine Kim; Gomperts, Brigitte; Hariri, Lida P.; Hogaboam, Cory M.; Jenkins, R. Gisli; Kaminski, Naftali; Kim, Grace Hyun J.; Konigshoff, Melanie; Kolb, Martin; Kotton, Darrell N.; Kropski, Jonathan A.; Lasky, Joseph; Magin, Chelsea M.; Maher, Toby M.; McCormick, Mark; Moore, Bethany B.; Nickerson-Nutter, Cheryl; Oldham, Justin; Podolanczuk, Anna J.; Raghu, Ganesh; Rosas, Ivan; Rowe, Steven M.; Schmidt, William T.; Schwartz, David; Shore, Jessica E.; Spino, Cathie; Craig, J. Matthew; Martinez, Fernando J. 分享 收藏
Activation of mTOR signaling in adult lung microvascular progenitor cells accelerates lung aging 成人肺微血管祖细胞中mTOR信号的激活加速了肺衰老 Mason, Emma C.; Menon, Swapna; Schneider, Benjamin R.; Gaskill, Christa F.; Dawson, Maggie M.; Moore, Camille M.; Armstrong, Laura Craig; Cho, Okyong; Richmond, Bradley W.; Kropski, Jonathan A.; West, James D.; Geraghty, Patrick; Gomperts, Brigitte N.; Ess, Kevin C.; Gally, Fabienne; Majka, Susan M. 分享 收藏
Targeting PEA3 transcription factors to mitigate small cell lung cancer progression Shia, David W. W.; Choi, WooSuk; Vijayaraj, Preethi; Vuong, Valarie; Sandlin, Jenna M. M.; Lu, Michelle M. M.; Aziz, Adam; Marin, Caliope; Aros, Cody J. J.; Sen, Chandani; Durra, Abdo; Lund, Andrew J. J.; Purkayastha, Arunima; Rickabaugh, Tammy M. M.; Graeber, Thomas G. G.; Gomperts, Brigitte N. N. 分享 收藏
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Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition Carraro, Gianni; Langerman, Justin; Sabri, Shan; Lorenzana, Zareeb; Purkayastha, Arunima; Zhang, Guangzhu; Konda, Bindu; Aros, Cody J.; Calvert, Ben A.; Szymaniak, Aleks; Wilson, Emily; Mulligan, Michael; Bhatt, Priyanka; Lu, Junjie; Vijayaraj, Preethi; Yao, Changfu; Shia, David W.; Lund, Andrew J.; Israely, Edo; Rickabaugh, Tammy M.; Ernst, Jason; Mense, Martin; Randell, Scott H.; Vladar, Eszter K.; Ryan, Amy L.; Plath, Kathrin; Mahoney, John E.; Stripp, Barry R.; Gomperts, Brigitte N. 分享 收藏
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery Mulay, Apoorva; Konda, Bindu; Garcia, Gustavo, Jr.; Yao, Changfu; Beil, Stephen; Villalba, Jaquelyn M.; Koziol, Colin; Sen, Chandani; Purkayastha, Arunima; Kolls, Jay K.; Pociask, Derek A.; Pessina, Patrizia; de Aja, Julio Sainz; Garcia-de-Alba, Carolina; Kim, Carla F.; Gomperts, Brigitte; Arumugaswami, Vaithilingaraja; Stripp, Barry R. 分享 收藏
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication Garcia, Gustavo, Jr.; Sharma, Arun; Ramaiah, Arunachalam; Sen, Chandani; Purkayastha, Arunima; Kohn, Donald B.; Parcells, Mark S.; Beck, Sebastian; Kim, Heeyoung; Bakowski, Malina A.; Kirkpatrick, Melanie G.; Riva, Laura; Wolff, Karen C.; Han, Brandon; Yuen, Constance; Ulmert, David; Purbey, Prabhat K.; Scumpia, Phillip; Beutler, Nathan; Rogers, Thomas F.; Chatterjee, Arnab K.; Gabriel, Guelsah; Bartenschlager, Ralf; Gomperts, Brigitte; Svendsen, Clive N.; Betz, Ulrich A. K.; Damoiseaux, Robert D.; Arumugaswami, Vaithilingaraja 分享 收藏
SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition Mullen, Peter J.; Garcia, Gustavo, Jr.; Purkayastha, Arunima; Matulionis, Nedas; Schmid, Ernst W.; Momcilovic, Milica; Sen, Chandani; Langerman, Justin; Ramaiah, Arunachalam; Shackelford, David B.; Damoiseaux, Robert; French, Samuel W.; Plath, Kathrin; Gomperts, Brigitte N.; Arumugaswami, Vaithilingaraja; Christofk, Heather R. 分享 收藏
Distinct Spatiotemporally Dynamic Wnt-Secreting Niches Regulate Proximal Airway Regeneration and Aging Aros, Cody J.; Vijayaraj, Preethi; Pantoja, Carla J.; Bisht, Bharti; Meneses, Luisa K.; Sandlin, Jenna M.; Tse, Jonathan A.; Chen, Michelle W.; Purkayastha, Arunima; Shia, David W.; Sucre, Jennifer Ms; Rickabaugh, Tammy M.; Vladar, Eszter K.; Paul, Manash K.; Gomperts, Brigitte N. 分享 收藏
High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis 高通量药物筛选确定了一种有效的Wnt抑制剂,可促进气道基底干细胞稳态 Aros, Cody J.; Paul, Manash K.; Pantoja, Carla J.; Bisht, Bharti; Meneses, Luisa K.; Vijayaraj, Preethi; Sandlin, Jenna M.; France, Bryan; Tse, Jonathan A.; Chen, Michelle W.; Shia, David W.; Rickabaugh, Tammy M.; Damoiseaux, Robert; Gomperts, Brigitte N. 分享 收藏
Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule Vijayaraj, Preethi; Minasyan, Aspram; Durra, Abdo; Karumbayaram, Saravanan; Mehrabi, Mehrsa; Aros, Cody J.; Ahadome, Sarah D.; Shia, David W.; Chung, Katherine; Sandlin, Jenna M.; Darmawan, Kelly F.; Bhatt, Kush V.; Manze, Chase C.; Paul, Manash K.; Wilkinson, Dan C.; Yan, Weihong; Clark, Amander T.; Rickabaugh, Tammy M.; Wallace, W. Dean; Graeber, Thomas G.; Damoiseaux, Robert; Gomperts, Brigitte N. 分享 收藏
Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization (vol 8, 217, 2017) Hazim, Roni A.; Karumbayaram, Saravanan; Jiang, Mei; Dimashkie, Anupama; Lopes, Vanda S.; Li, Douran; Burgess, Barry L.; Vijayaraj, Preethi; Alva-Ornelas, Jackelyn A.; Zack, Jerome A.; Kohn, Donald B.; Gomperts, Brigitte N.; Pyle, April D.; Lowry, William E.; Williams, David S. 分享 收藏
Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells Walser, Tonya C.; Jing, Zhe; Tran, Linh M.; Lin, Ying Q.; Yakobian, Natalie; Wang, Gerald; Krysan, Kostyantyn; Zhu, Li X.; Sharma, Sherven; Lee, Mi-Heon; Belperio, John A.; Ooi, Aik T.; Gomperts, Brigitte N.; Shay, Jerry W.; Larsen, Jill E.; Minna, John D.; Hong, Long-sheng; Fishbein, Michael C.; Dubinett, Steven M. 分享 收藏