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Weifan Zheng

University of Illinois Chicago

H指数:21

被引数:1,817

个人简介

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工作经历

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荣誉奖项

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Machine learning analysis of gene expression profiles of pyroptosis-related differentially expressed genes in ischemic stroke revealed potential targets for drug repurposing

SCIENTIFIC REPORTS

IF3.9

2025-02-270

OAAI

Identification of Novel GANT61 Analogs with Activity in Hedgehog Functional Assays and GLI1-Dependent Cancer Cells

IF4.6

2024-06-282

OAAI

Lead/Drug Discovery from Natural Resources

从自然资源中发现铅/药物

IF4.6

2022-11-2818

OAAI

Cheminformatics Modeling of Gene Silencing for Both Natural and Chemically Modified siRNAs

天然和化学修饰的siRNAs基因沉默的化学信息学建模

IF4.6

2022-09-282

OAAI

Original Learning Drug-Disease-Target Embedding (DDTE) from knowledge graphs to inform drug repurposing hypotheses

来自知识图的原始学习药物-疾病-目标嵌入 (DDTE)，以告知药物再利用假设

JOURNAL OF BIOMEDICAL INFORMATICS

IF4.5

2021-07-0119

OAAI

A semantic similarity based methodology for predicting protein-protein interactions: Evaluation with P53-interacting kinases

JOURNAL OF BIOMEDICAL INFORMATICS

IF4.5

2020-11-012

OAAI

Literature-Wide Association Studies (LWAS) for a Rare Disease: Drug Repurposing for Inflammatory Breast Cancer

IF4.6

2020-08-285

OAAI

TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation

CELL DEATH & DISEASE

IF9.6

2020-03-0936

OAAI

Oncogenic Role of Tumor Necrosis Factor α-Induced Protein 8 (TNFAIP8)

IF5.2

2018-12-2447

OAAI

Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2016-04-1234

OAAI

Scoring protein interaction decoys using exposed residues (SPIDER): A novel multibody interaction scoring function based on frequent geometric patterns of interfacial residues

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2012-06-0740

OAAI

Structure-based quantitative structure-activity relationship modeling of estrogen receptor β-ligands

FUTURE MEDICINAL CHEMISTRY

IF3.4

2011-06-275

PREAI

A Novel Structure-Based Multimode QSAR Method Affords Predictive Models for Phosphodiesterase Inhibitors

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2010-01-229

PRE

Structure-based shape pharmacophore modeling for the discovery of novel anesthetic compounds

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2009-07-0113

PREAI

Unconventional 2D Shape Similarity Method Affords Comparable Enrichment as a 3D Shape Method in Virtual Screening Experiments

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2009-05-2913

PREAI

From anesthetic mechanisms research to drug discovery

从麻醉机制研究到药物发现

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2008-04-3015

PREAI

Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2008-04-0957

PRE

Antitumor Agents 252. Application of validated QSAR models to database mining: discovery of novel tylophorine derivatives as potential anticancer agents

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2007-03-0689

OA

Recent progress in the computational prediction of aqueous solubility and absorption

IF3.7

2006-03-0178

OA

Quantitative structure-activity relationship modeling of dopamine D1 antagonists using comparative molecular field analysis, genetic algorithms-partial least-squares, and K nearest neighbor methods

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

1999-08-0397

PREAI