未登录NRF2 supports non-small cell lung cancer growth independently of CBP/p300-enhanced glutathione synthesisNRF2支持非小细胞肺癌的生长，且该作用独立于CBP/p300增强的谷胱甘肽合成。
Conrad, Ryan J.; Mondo, James A.; Wang, Mike Lingjue; Liu, Peter S.; Lai, Zijuan; Choudhury, Feroza K.; Li, Qingling; Wong, Weng Ruh; Lee, James; Shanahan, Frances; Lin, Eva; Martin, Scott; Rudolph, Joachim; Moffat, John G.; Sangaraju, Dewakar; Sandoval, Wendy; Sterne-Weiler, Timothy; Foster, Scott A. .png)
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收藏A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth一种非酶依赖性，依赖于inositol-requiring enzyme 1的控制癌症细胞周期进展和肿瘤生长。Zuazo-Gaztelu, Iratxe; Lawrence, David; Oikonomidi, Ioanna; Marsters, Scot; Pechuan-Jorge, Ximo; Gaspar, Catarina J.; Kan, David; Segal, Ehud; Clark, Kevin; Beresini, Maureen; Braun, Marie-Gabrielle; Rudolph, Joachim; Modrusan, Zora; Choi, Meena; Sandoval, Wendy; Reichelt, Mike; Dewitt, David C.; Kujala, Pekka; van Dijk, Suzanne; Klumperman, Judith 分享 收藏 Inhibition of GPX4 enhances CDK4/6 inhibitor and endocrine therapy activity in breast cancerHerrera-Abreu, M. T.; Guan, J.; Khalid, U.; Ning, J.; Costa, M. R.; Chan, J.; Li, Q.; Fortin, J-p.; Wong, W. R.; Perampalam, P.; Biton, A.; Sandoval, W.; Vijay, J.; Hafner, M.; Cutts, R.; Wilson, G.; Frankum, J.; Roumeliotis, T. I.; Alexander, J.; Hickman, O.; Brough, R.; Haider, S.; Choudhary, J.; Lord, C. J.; Swain, A.; Metcalfe, C.; Turner, N. C. 分享 收藏 The discovery and structural basis of two distinct state-dependent inhibitors of BamASun, Dawei; Storek, Kelly M.; Tegunov, Dimitry; Yang, Ying; Arthur, Christopher P.; Johnson, Matthew; Quinn, John G.; Liu, Weijing; Han, Guanghui; Girgis, Hany S.; Alexander, Mary Kate; Murchison, Austin K.; Shriver, Stephanie; Tam, Christine; Ijiri, Hiroshi; Inaba, Hiroko; Sano, Tatsuya; Yanagida, Hayato; Nishikawa, Junichi; Heise, Christopher E.; Fairbrother, Wayne J.; Tan, Man-Wah; Skelton, Nicholas; Sandoval, Wendy; Sellers, Benjamin D.; Ciferri, Claudio; Smith, Peter A.; Reid, Patrick C.; Cunningham, Christian N.; Rutherford, Steven T.; Payandeh, Jian 分享 收藏 Top-down mass spectrometry of native proteoforms and their complexes: a community studyHabeck, Tanja; Brown, Kyle A.; Des Soye, Benjamin; Lantz, Carter; Zhou, Mowei; Alam, Novera; Hossain, Md Amin; Jung, Wonhyeuk; Keener, James E.; Volny, Michael; Wilson, Jesse W.; Ying, Yujia; Agar, Jeffrey N.; Danis, Paul O.; Ge, Ying; Kelleher, Neil L.; Li, Huilin; Loo, Joseph A.; Marty, Michael T.; Pasa-Tolic, Ljiljana; Sandoval, Wendy; Lermyte, Frederik 分享 收藏 Exposing the molecular heterogeneity of glycosylated biotherapeuticsSchachner, Luis F.; Mullen, Christopher; Phung, Wilson; Hinkle, Joshua D.; Beardsley, Michelle Irwin; Bentley, Tracy; Day, Peter; Tsai, Christina; Sukumaran, Siddharth; Baginski, Tomasz; Dicara, Danielle; Agard, Nicholas J.; Masureel, Matthieu; Gober, Joshua; ElSohly, Adel M.; Melani, Rafael; Syka, John E. P.; Huguet, Romain; Marty, Michael T.; Sandoval, Wendy 分享 收藏 Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40Shatz-Binder, Whitney; Azumaya, Caleigh M.; Leonard, Brandon; Vuong, Ivan; Sudhamsu, Jawahar; Rohou, Alexis; Liu, Peter; Sandoval, Wendy; Bol, Karenna; Izadi, Saeed; Holder, Patrick G.; Blanchette, Craig; Perozzo, Remo; Kelley, Robert F.; Kalia, Yogeshvar 分享 收藏 分享 收藏 Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors联合PD-L1/tgf β 阻断可在免疫排除的肿瘤中扩增和分化干细胞样CD8 T细胞Castiglioni, Alessandra; Yang, Yagai; Williams, Katherine; Gogineni, Alvin; Lane, Ryan S.; Wang, Amber W.; Shyer, Justin A.; Zhang, Zhe; Mittman, Stephanie; Gutierrez, Alan; Astarita, Jillian L.; Thai, Minh; Hung, Jeffrey; Yang, Yeqing Angela; Pourmohamad, Tony; Himmels, Patricia; De Simone, Marco; Elstrott, Justin; Capietto, Aude-Helene; Cubas, Rafael; Modrusan, Zora; Sandoval, Wendy; Ziai, James; Gould, Stephen E.; Fu, Wenxian; Wang, Yulei; Koerber, James T.; Sanjabi, Shomyseh; Mellman, Ira; Turley, Shannon J.; Mueller, Soeren 分享 收藏 分享 收藏 分享 收藏 LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lungMa, Hsiao-Yen; Li, Qingling; Wong, Weng Ruh; N'Diaye, Elsa-Noah; Caplazi, Patrick; Bender, Hannah; Huang, Zhiyu; Arlantico, Alexander; Jeet, Surinder; Wong, Aaron; Emson, Claire; Brightbill, Hans; Tam, Lucinda; Newman, Robert; Roose-Girma, Merone; Sandoval, Wendy; Ding, Ning 分享 收藏 Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanismsHecht, Elizabeth Sara; Mehta, Shrenik; Wecksler, Aaron T.; Aguilar, Ben; Swanson, Nathaniel; Phung, Wilson; Kelsoe, Ananya Dubey; Benner, W. Henry; Tesar, Devin; Kelley, Robert F.; Sandoval, Wendy; Sreedhara, Alavattam 分享 收藏 High-Throughput, Quantitative Analysis of Peptide-Exchanged MHCI Complexes by Native Mass SpectrometrySchachner, Luis F.; Phung, Wilson; Han, Guanghui; Darwish, Martine; Bell, Ashley; Mellors, J. Scott; Srzentic, Kristina; Huguet, Romain; Blanchette, Craig; Sandoval, Wendy 分享 收藏 Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii先前未表征的脂蛋白lirL的缺失赋予鲍曼不动杆菌对II型信号肽酶抑制剂的抗性Huang, Ke-Jung; Pantua, Homer; Diao, Jingyu; Skippington, Elizabeth; Volny, Michael; Sandoval, Wendy; Tiku, Varnesh; Peng, Yutian; Sagolla, Meredith; Yan, Donghong; Kang, Jing; Katakam, Anand Kumar; Michaelian, Nairie; Reichelt, Mike; Tan, Man-Wah; Austin, Cary D.; Xu, Min; Hanan, Emily; Kapadia, Sharookh B. 分享 收藏 分享 收藏 BMP1 is not required for lung fibrosis in miceMa, Hsiao-Yen; N'diaye, Elsa-Noah; Caplazi, Patrick; Huang, Zhiyu; Arlantico, Alexander; Jeet, Surinder; Wong, Aaron; Brightbill, Hans D.; Li, Qingling; Wong, Weng Ruth; Sandoval, Wendy; Tam, Lucinda; Newman, Robert; Roose-Girma, Merone; Ding, Ning 分享 收藏 In vivo partial reprogramming alters age-associated molecular changes during physiological aging in miceBrowder, Kristen C.; Reddy, Pradeep; Yamamoto, Mako; Haghani, Amin; Guillen, Isabel Guillen; Sahu, Sanjeeb; Wang, Chao; Luque, Yosu; Prieto, Javier; Shi, Lei; Shojima, Kensaku; Hishida, Tomoaki; Lai, Zijuan; Li, Qingling; Choudhury, Feroza K.; Wong, Weng R.; Liang, Yuxin; Sangaraju, Dewakar; Sandoval, Wendy; Esteban, Concepcion Rodriguez; Nunez Delicado, Estrella; Guillen Garcia, Pedro; Pawlak, Michal; Vander Heiden, Jason A.; Horvath, Steve; Jasper, Heinrich; Belmonte, Juan Carlos Izpisua 分享 收藏 分享 收藏 Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissuesKapoor, Varun N.; Muller, Soren; Keerthivasan, Shilpa; Brown, Markus; Chalouni, Cecile; Storm, Elaine E.; Castiglioni, Alessandra; Lane, Ryan; Nitschke, Maximilian; Dominguez, Claudia X.; Astarita, Jillian L.; Krishnamurty, Akshay T.; Carbone, Catherine B.; Senbabaoglu, Yasin; Wang, Amber W.; Wu, Xiumin; Cremasco, Viviana; Roose-Girma, Merone; Tam, Lucinda; Doerr, Jonas; Chen, Mark Z.; Lee, Wyne P.; Modrusan, Zora; Yang, Yeqing Angela; Bourgon, Richard; Sandoval, Wendy; Shaw, Andrey S.; de Sauvage, Frederic J.; Mellman, Ira; Moussion, Christine; Turley, Shannon J. 分享 收藏 
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