未登录 The N-terminal PA domains of signal-peptide-peptidase-like 2 (SPPL2) proteases impact on TNFα cleavage 信号肽肽酶样2（SPPL2）蛋白酶的N端PA结构域对TNFα的切割产生影响 Schlosser, Christine; Sharrouf, Kinda; Papadopoulou, Alkmini A.; Haug-Kroeper, Martina; Singh, Suman; Johler, Maximilian; Pettinger, Jonas; Horn, Henrike; Koch, Marco; Hoeppner, Sabine; Fluhrer, Regina 分享 收藏
The DNase TREX1 is a substrate of the intramembrane protease SPP with implications for disease pathogenesis DNase TREX1是跨膜蛋白酶SPP的底物，与疾病发病机制有关。 Tever, Onur Kerem; Mentrup, Torben; Chinn, Ivan Kingyue; Ishikuma, Hitoshi; Fluhrer, Regina; Schmitz, Marc; Wehner, Rebekka; Behrendt, Rayk; Chinen, Javier; Schroeder, Bernd 分享 收藏
Signal peptide peptidase-like 2b modulates the amyloidogenic pathway and exhibits an Aβ-dependent expression in Alzheimer's disease 信号肽肽酶样2b调节淀粉样蛋白生成途径并在阿尔茨海默氏病中表现出a β 依赖性表达 Maccioni, Riccardo; Travisan, Caterina; Badman, Jack; Zerial, Stefania; Wagener, Annika; Andrade-Talavera, Yuniesky; Picciau, Federico; Grassi, Caterina; Chen, Gefei; Lemoine, Laetitia; Fisahn, Andre; Jiang, Richeng; Fluhrer, Regina; Mentrup, Torben; Schroeder, Bernd; Nilsson, Per; Tambaro, Simone 分享 收藏
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The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo Schneppenheim, Janna; Huettl, Susann; Mentrup, Torben; Luellmann-Rauch, Renate; Rothaug, Michelle; Engelke, Michael; Dittmann, Kai; Dressel, Ralf; Araki, Masatake; Araki, Kimi; Wienands, Juergen; Fluhrer, Regina; Saftig, Paul; Schroeder, Bernd 分享 收藏
Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage Papadopoulou, Alkmini A.; Stelzer, Walter; Silber, Mara; Schlosser, Christine; Spitz, Charlotte; Haug-Kroeper, Martina; Straub, Tobias; Mueller, Stephan A.; Lichtenthaler, Stefan F.; Muhle-Goll, Claudia; Langosch, Dieter; Fluhrer, Regina 分享 收藏
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19 Heard, Amanda; Landmann, Jack H.; Hansen, Ava R.; Papadopolou, Alkmini; Hsu, Yu-Sung; Selli, Mehmet Emrah; Warrington, John M.; Lattin, John; Chang, Jufang; Ha, Helen; Haug-Kroeper, Martina; Doray, Balraj; Gill, Saar; Ruella, Marco; Hayer, Katharina E.; Weitzman, Matthew D.; Green, Abby M.; Fluhrer, Regina; Singh, Nathan 分享 收藏
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis 膜内蛋白水解终止了C型凝集素受体Dectin-1的吞噬体信号传导 Mentrup, Torben; Stumpff-Niggemann, Anna Yamina; Leinung, Nadja; Schlosser, Christine; Schubert, Katja; Wehner, Rebekka; Tunger, Antje; Schatz, Valentin; Neubert, Patrick; Gradtke, Ann-Christine; Wolf, Janina; Rose-John, Stefan; Saftig, Paul; Dalpke, Alexander; Jantsch, Jonathan; Schmitz, Marc; Fluhrer, Regina; Jacobsen, Ilse D.; Schroeder, Bernd 分享 收藏
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Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins (vol 20, e46451, 2019) Papadopoulou, Alkmini A.; Mueller, Stephan A.; Mentrup, Torben; Shmueli, Merav D.; Niemeyer, Johannes; Haug-Kroper, Martina; von Blume, Julia; Mayerhofer, Artur; Feederle, Regina; Schroeder, Bernd; Lichtenthaler, Stefan F.; Fluhrer, Regina 分享 收藏
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis Mentrup, Torben; Theodorou, Kosta; Cabrera-Cabrera, Florencia; Hethig, Andreas O.; Happ, Kathrin; Gijbels, Marion; Gradtke, Ann-Christine; Rabe, Bjoern; Fukumori, Akio; Steiner, Harald; Tholey, Andreas; Fluhrer, Regina; Donners, Marjo; Schroeder, Bernd 分享 收藏
Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleavage of SNARE proteins Papadopoulou, Alkmini A.; Mueller, Stephan A.; Mentrup, Torben; Shmueli, Merav D.; Niemeyer, Johannes; Haug-Kroeper, Martina; von Blume, Julia; Mayerhofer, Artur; Feederle, Regina; Schroeder, Bernd; Lichtenthaler, Stefan F.; Fluhrer, Regina 分享 收藏
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban Niemeyer, Johannes; Mentrup, Torben; Heidasch, Ronny; Mueller, Stephan A.; Biswas, Uddipta; Meyer, Rieke; Papadopoulou, Alkmini A.; Dederer, Verena; Haug-Kroeper, Martina; Adamski, Vivian; Luellmann-Rauch, Renate; Bergmann, Martin; Mayerhofer, Artur; Saftig, Paul; Wennemuth, Gunther; Jessberger, Rolf; Fluhrer, Regina; Lichtenthaler, Stefan F.; Lemberg, Marius K.; Schroeder, Bernd 分享 收藏
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Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases Fleck, Daniel; Voss, Matthias; Brankatschk, Ben; Giudici, Camilla; Hampel, Heike; Schwenk, Benjamin; Edbauer, Dieter; Fukumori, Akio; Steiner, Harald; Kremmer, Elisabeth; Haug-Kroeper, Martina; Rossner, Moritz J.; Fluhrer, Regina; Willem, Michael; Haass, Christian 分享 收藏
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