Christopher V. Nicchitta

Duke University Medical Center

57H指数

195论文数

8.7K被引数

收录论文 74

发表时间

The PAXT connection is a modifier of rare codon-enriched protein expression PAXT连接是一种稀有密码子富集蛋白表达的修饰因子

Nature Communications

IF15.7

2026-09-17

OAAI

Taylor Niehoff; Jackson Peterson; Siqi Li; Sijin Chen; Christopher V. Nicchitta; Alain Laederach; Christopher M. Counter

Programmable mRNA 3′UTR engineering restores MHC-I and overcomes immune evasion in prostate cancer 可编程mRNA 3'utr工程恢复mhc-i并克服前列腺癌中的免疫逃避

Nature Biomedical Engineering

IF26.6

2026-06-16

PREAI

Furong Huang; Fuwen Yuan; Kexin Li; Ya Cui; Lei Li; Wenbin Ye; Zhifen Cui; Jingyue Yan; Qiang Chen; Christopher Nicchitta; Yuebao Zhang; William Hankey; Jeffrey Everitt; Kai-Lieh Huang; Mu-En Wang; Ming Chen; Jiaoti Huang; Hongyan Wang; Eric J. Wagner; Xin Lu; Yizhou Dong; Wei Li; Qianben Wang

Correction: Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane 校正：定量蛋白质组学将LRRC59相互作用组与内质网膜上的mRNA翻译联系起来

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2026-05-13

OAAI

Molly M. Hannigan; Alyson M. Hoffman; J. Will Thompson; Tianli Zheng; Christopher V. Nicchitta

An atypical form of 60S ribosomal subunit in Diamond-Blackfan anemia linked to RPL17 variants

JCI INSIGHT

IF6.1

2024-08-01

OAAI

Fellmann, Florence; Saunders, Carol; O'Donohue, Marie-Francoise; Reid, David W.; Mcfadden, Kelsey A.; Montel-Lehry, Nathalie; Yu, Cong; Fang, Mingyan; Zhang, Jianguo; Royer-Bertrand, Beryl; Farinelli, Pietro; Karboul, Narjesse; Willer, Jason R.; Fievet, Lorraine; Bhuiyan, Zahurul Alam; Kleinhenz, Alissa L. W.; Jadeau, Julie; Fulbright, Joy; Rivolta, Carlo; Renella, Raffaele; Katsanis, Nicholas; Beckmann, Jacques S.; V. Nicchitta, Christopher; Da Costa, Lydie; Davis, Erica E.; Gleizes, Pierre-Emmanuel

Targeted engineering mRNA 3'UTR length enhances immunotherapy response in prostate cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Huang, Furong; Yuan, Fuwen; Cui, Ya; Li, Lei; Li, Kexin; Cui, Zhifen; Yan, Jingyue; Chen, Qiang; Nicchitta, Christopher; Ye, Wenbin; Zhang, Yuebao; Hankey, William; Everitt, Jeffrey; Chen, Ming; Huang, Jiaoti; Wang, Hongyan; Lu, Xin; Wagner, Eric; Dong, Yizhou; Li, Wei; Wang, Qianben

An emerging role for the endoplasmic reticulum in stress granule biogenesis 内质网在应激颗粒生物发生中的新兴作用

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2024-03-01

PREAI

Nicchitta, Christopher V.

High-throughput quantitation of protein-RNA UV-crosslinking efficiencies as a predictive tool for high-confidence identification of RNA-binding proteins 蛋白质-RNA UV交联效率的高通量定量作为高置信度鉴定RNA结合蛋白的预测工具

RNA

IF5

2024-02-29

PREAI

Kristofich, Johncarlo; Nicchitta, Christopher V.

Signal-noise metrics for RNA binding protein identification reveal broad spectrum protein-RNA interaction frequencies and dynamics

NATURE COMMUNICATIONS

IF15.7

2023-09-21

OAAI

Kristofich, JohnCarlo; Nicchitta, Christopher V.

Cooperative regulation of coupled oncoprotein synthesis and stability in triple-negative breast cancer by EGFR and CDK12/13

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-09-11

OAAI

Ang, Hazel X.; Sutiman, Natalia; Deng, Xinyue L.; Liu, Annie; Cerda-Smith, Christian G.; Hutchinson, Haley M.; Kim, Holly; Bartelt, Luke C.; Chen, Qiang; Barrera, Alejandro; Lin, Jiaxing; Sheng, Zhecheng; McDowell, Ian C.; Reddy, Timothy E.; Nicchitta, Christopher V.; Wood, Kris C.

Examining SRP pathway function in mRNA localization to the endoplasmic reticulum

RNA

IF5

2023-08-29

PREAI

Child, Jessica R.; Hofler, Alex C.; Chen, Qiang; Yang, Brenda H.; Kristofich, Johncarlo; Zheng, Tianli; Hannigan, Molly M.; Elles, Andrew L.; Reid, David W.; Nicchitta, Christopher V.

Complementary Roles of GADD34-and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response 含GADD34-and CReP的真核起始因子2α 磷酸酶在未折叠蛋白反应中的互补作用

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Reid, David W.; Tay, Angeline S. L.; Sundaram, Jeyapriya R.; Lee, Irene C. J.; Chen, Qiang; George, Simi E.; Nicchitta, Christopher V.; Shenolikar, Shirish

ABL kinases regulate translation in HER2+cells through Y-box-binding protein 1 to facilitate colonization of the brain

CELL REPORTS

IF6.9

2022-08-01

OAAI

McKernan, Courtney M.; Khatri, Aaditya; Hannigan, Molly; Child, Jessica; Chen, Qiang; Mayro, Benjamin; Snyder, David; V. Nicchitta, Christopher; Pendergast, Ann Marie

Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules 将内质网靶向和胞质mrna募集到膜相关应激颗粒中

RNA

IF5

2021-07-08

OAAI

Child, Jessica R.; Chen, Qiang; Reid, David W.; Jagannathan, Sujatha; Nicchitta, Christopher, V

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2020-11-01

OAAI

Hannigan, Molly M.; Hoffman, Alyson M.; Thompson, J. Will; Zheng, Tianli; Nicchitta, Christopher, V

y Heterogeneous translational landscape of the endoplasmic reticulum revealed by ribosome proximity labeling and transcriptome analysis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-05-01

OAAI

Hoffman, Alyson M.; Chen, Qiang; Zheng, Tianli; Nicchitta, Christopher V.

Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis

JOURNAL OF VIROLOGY

IF3.8

2018-04-01

OAAI

Reid, David W.; Campos, Rafael K.; Child, Jessica R.; Zheng, Tianli; Chan, Kitti Wing Ki; Bradrick, Shelton S.; Vasudevan, Subhash G.; Garcia-Blanco, Mariano A.; Nicchitta, Christopher V.

Oncoprotein AEG-1 is an endoplasmic reticulum RNA-binding protein whose interactome is enriched in organelle resident protein-encoding mRNAs 癌蛋白AEG-1是一种内质网RNA结合蛋白，其相互作用组富含细胞器驻留蛋白编码mrna

RNA

IF5

2018-02-07

OAAI

Hsu, Jack C. -C.; Reid, David W.; Hoffman, Alyson M.; Sarkar, Devanand; Nicchitta, Christopher V.

Simple and inexpensive ribosome profiling analysis of mRNA translation mRNA翻译的简单而廉价的核糖体谱分析

METHODS

IF4.3

2015-12-01

OAAI

Reid, David W.; Shenolikar, Shirish; Nicchitta, Christopher V.

Diversity and selectivity in mRNA translation on the endoplasmic reticulum 内质网上mRNA翻译的多样性和选择性

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2015-03-04

209

OAAI

Reid, David W.; Nicchitta, Christopher V.

A Novel Ribosomopathy Caused by Dysfunction of RPL10 Disrupts Neurodevelopment and Causes X-Linked Microcephaly in Humans 由RPL10功能障碍引起的新型核糖病变会破坏神经发育并导致人类X连锁小头畸形

GENETICS

IF5.1

2014-10-01

OAAI

Brooks, Susan S.; Wall, Alissa L.; Golzio, Christelle; Reid, David W.; Kondyles, Amalia; Willer, Jason R.; Botti, Christina; Nicchitta, Christopher V.; Katsanis, Nicholas; Davis, Erica E.

研究方向