未登录 N-Branched Tricyclic Guanidines as Novel Melanocortin-3 Receptor Agonists and Melanocortin-4 Receptor Antagonists N-支链三环胍类化合物作为新型促黑激素-3受体激动剂和促黑激素-4受体拮抗剂 Weirath, Nicholas A.; Zajac, Jonathan W. P.; Donow, Haley M.; Lavoi, Travis M.; Pinilla, Clemencia; Santos, Radleigh G.; Prajapati, Ritu; Speth, Robert; Ericson, Mark D.; Sarupria, Sapna; Giulianotti, Marcello A. 分享 收藏
Lab on a chip (LOC) platform for drug screening against the intracellular forms of Trypanosoma cruzi Cadena, Maria Fernanda; Rosero-Yanez, Gustavo; Isa-Jara, Ramiro; Belaunzaran, Maria Laura; Giulianotti, Marc A.; Pinilla, Clemencia; Soto, Catalina D. Alba; Perez, Maximiliano; Lerner, Betiana; Gimenez, Guadalupe 分享 收藏
Ag-driven CD8+ T cell clonal expansion is a prominent feature of MASH in humans and mice Burtis, Abbigayl E. C.; Denicola, Destiny M. C.; Ferguson, Megan E.; Santos, Radleigh G.; Pinilla, Clemencia; Kriss, Michael S.; Orlicky, David J.; Tamburini, Beth A. Jiron; Gillen, Austin E.; Burchill, Matthew A. 分享 收藏
Structure-Activity Relationship of Pyrrolidine Pentamine Derivatives as Inhibitors of the Aminoglycoside 6′-N-Acetyltransferase Type Ib Sklenicka, Jan; Tran, Tung; Ramirez, Maria S.; Donow, Haley M.; Magana, Angel J.; Lavoi, Travis; Mamun, Yasir; Jimenez, Veronica; Chapagain, Prem; Santos, Radleigh; Pinilla, Clemencia; Giulianotti, Marc A.; Tolmasky, Marcelo E. 分享 收藏
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput 'Unbiased' Screening Campaign (vol 64, pg 5577, 2021) Doering, Skye R.; Freeman, Katie; Debevec, Ginamarie; Geer, Phaedra; Santos, Radleigh G.; Lavoi, Travis M.; Giulianotti, Marc A.; Pinilla, Clemencia; Appel, Jon R.; Houghten, Richard A.; Ericson, Mark D.; Haskell-Luevano, Carrie 分享 收藏
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Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist Ericson, Mark D.; Doering, Skye R.; Larson, Courtney M.; Freeman, Katie T.; LaVoi, Travis M.; Donow, Haley M.; Santos, Radleigh G.; Cho, Rachel H.; Koerperich, Zoe M.; Giulianotti, Marc A.; Pinilla, Clemencia; Houghten, Richard A.; Haskell-Luevano, Carrie 分享 收藏
Inhibition of Aminoglycoside 6′-N-acetyltransferase Type Ib (AAC(6′)-Ib): Structure-Activity Relationship of Substituted Pyrrolidine Pentamine Derivatives as Inhibitors Rocha, Kenneth; Magallon, Jesus; Reeves, Craig; Phan, Kimberly; Vu, Peter; Oakley-Havens, Crista L.; Kwan, Stella; Ramirez, Maria Soledad; LaVoi, Travis; Donow, Haley; Chapagain, Prem; Santos, Radleigh; Pinilla, Clemencia; Giulianotti, Marc A.; Tolmasky, Marcelo E. 分享 收藏
CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope Greaves, Sarah A.; Ravindran, Avinash; Santos, Radleigh G.; Chen, Lan; Falta, Michael T.; Wang, Yang; Mitchell, Angela M.; Atif, Shaikh M.; Mack, Douglas G.; Tinega, Alex N.; Maier, Lisa A.; Dai, Shaodong; Pinilla, Clemencia; Grunewald, Johan; Fontenot, Andrew P. 分享 收藏
Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire Brown, Ivy K.; Dyjack, Nathan; Miller, Mindy M.; Krovi, Harsha; Rios, Cydney; Woolaver, Rachel; Harmacek, Laura; Tu, Ting-Hui; O'Connor, Brian P.; Danhorn, Thomas; Vestal, Brian; Gapin, Laurent; Pinilla, Clemencia; Seibold, Max A.; Scott-Browne, James; Santos, Radleigh G.; Reinhardt, R. Lee 分享 收藏
Beryllium-specific CD4+T cells induced by chemokine neoantigens perpetuate inflammation Falta, Michael T.; Crawford, Jeremy C.; Tinega, Alex N.; Landry, Laurie G.; Crawford, Frances; Mack, Douglas G.; Martin, Allison K.; Atif, Shaikh M.; Li, Li; Santos, Radleigh G.; Nakayama, Maki; Kappler, John W.; Maier, Lisa A.; Thomas, Paul G.; Pinilla, Clemencia; Fontenot, Andrew P. 分享 收藏
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput Unbiased Screening Campaign Doering, Skye R.; Freeman, Katie; Debevec, Ginamarie; Geer, Phaedra; Santos, Radleigh G.; Lavoi, Travis M.; Giulianotti, Marc A.; Pinilla, Clemencia; Appel, Jon R.; Houghten, Richard A.; Ericson, Mark D.; Haskell-Luevano, Carrie 分享 收藏
The value of antimicrobial peptides in the age of resistance 抗菌肽在耐药时代的价值 Magana, Maria; Pushpanathan, Muthuirulan; Santos, Ana L.; Leanse, Leon; Fernandez, Michael; Ioannidis, Anastasios; Giulianotti, Marc A.; Apidianakis, Yiorgos; Bradfute, Steven; Ferguson, Andrew L.; Cherkasov, Artem; Seleem, Mohamed N.; Pinilla, Clemencia; de la Fuente-Nunez, Cesar; Lazaridis, Themis; Dai, Tianhong; Houghten, Richard A.; Hancock, Robert E. W.; Tegos, George P. 分享 收藏
Discovery of Polypharmacological Melanocortin-3 and-4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a μM MC4R Partial Agonist Fleming, Katlyn A.; Freeman, Katie T.; Powers, Mike D.; Santos, Radleigh G.; Debevec, Ginamarie; Giulianotti, Marc A.; Houghten, Richard A.; Doering, Skye R.; Pinilla, Clemencia; Haskell-Luevano, Carrie 分享 收藏
GDP-L-fucose synthase is a CD4+ T cell-specific autoantigen in DRB3*02:02 patients with multiple sclerosis Gdp-l-岩藻糖合酶是02:02 DRB3的多发性硬化症患者的CD4 T细胞特异性自身抗原 Planas, Raquel; Santos, Radleigh; Tomas-Ojer, Paula; Cruciani, Carolina; Lutterotti, Andreas; Faigle, Wolfgang; Schaeren-Wiemers, Nicole; Espejo, Carmen; Eixarch, Herena; Pinilla, Clemencia; Martin, Roland; Sospedra, Mireia 分享 收藏
Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2 Doering, Skye R.; Freeman, Katie T.; Schnell, Sathya M.; Haslach, Erica M.; Dirain, Marvin; Debevec, Ginamarie; Geer, Phaedra; Santos, Radleigh G.; Giulianotti, Marc A.; Pinilla, Clemencia; Appel, Jon R.; Speth, Robert C.; Houghten, Richard A.; Haskell-Luevano, Carrie 分享 收藏
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Improvement of IFNγ ELISPOT Performance Following Overnight Resting of Frozen PBMC Samples Confirmed Through Rigorous Statistical Analysis (vol 4, pg 1, 2015) Santos, Radleigh; Buying, Alcinette; Sabri, Nazila; Yu, John; Gringeri, Anthony; Bender, James; Janetzki, Sylvia; Pinilla, Clemencia; Judkowski, Valeria A. 分享 收藏
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Cytokine Production but Lack of Proliferation in Peripheral Blood Mononuclear Cells from Chronic Chagas' Disease Cardiomyopathy Patients in Response to T. cruzi Ribosomal P Proteins Longhi, Silvia A.; Atienza, Augusto; Perez Prados, Graciela; Buying, Alcinette; Balouz, Virginia; Buscaglia, Carlos A.; Santos, Radleigh; Tasso, Laura M.; Bonato, Ricardo; Chiale, Pablo; Pinilla, Clemencia; Judkowski, Valeria A.; Gomez, Karina A. 分享 收藏
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