未登录Loss of the maternal effect gene NLRP2 impairs embryonic and extra-embryonic development, revealing a novel genetic cause of congenital anomalies†
Sharif, Momal; Anvar, Zahra; Chakchouk, Imen; El-Dessouky, Sara H.; Zemet, Roni; Kao, Eric C.; Sharaf-Eldin, Wessam E.; Wan, Ying-Wooi; Liu, Zhandong; Liu, Pengfei; Jochum, Michael; Van Den Veyver, Ignatia B. .png)
分享.png)
收藏Multi-omics delineate growth factor network underlying exercise effects in an Alzheimer's mouse model多组学描绘了运动效应在阿尔茨海默病小鼠模型中生长因子网络的内在机制Li, X; Liu, CZ; Li, WB; Qi, GT; Dai, YW; Gu, CH; Sun, YX; Zhou, WJ; Ciliberto, VC; Liang, J; Kumar, SU; Guan, DY; Hu, ZY; Zheng, H; Liu, ZD; Chen, H; Wan, YW; Sun, Z 分享 收藏 Modeling antisense oligonucleotide therapy in MECP2 duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levelsBajikar, Sameer S.; Sztainberg, Yehezkel; Trostle, Alexander J.; Tirumala, Harini P.; Wan, Ying-Wooi; Harrop, Caroline L.; Bengtsson, Jesse D.; Carvalho, Claudia M. B.; Pehlivan, Davut; Suter, Bernhard; Neul, Jeffrey L.; Liu, Zhandong; Jafar-Nejad, Paymaan; Rigo, Frank; Zoghbi, Huda Y. 分享 收藏 MATR3 pathogenic variants differentially impair its cryptic splicing repression functionKhan, Mashiat; Chen, Xiao Xiao Lily; Dias, Michelle; Santos, Jhune Rizsan; Kour, Sukhleen; You, Justin; van Bruggen, Rebekah; Youssef, Mohieldin M. M.; Wan, Ying-Wooi; Liu, Zhandong; Rosenfeld, Jill A.; Tan, Qiumin; Pandey, Udai Bhan; Yalamanchili, Hari Krishna; Park, Jeehye 分享 收藏 分享 收藏 Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1 (vol 111, pg 481, 2023)Coffin, Stephanie L.; Durham, Mark A.; Nitschke, Larissa; Xhako, Eder; Brown, Amanda M.; Revelli, Jean-Pierre; Gonzalez, Esmeralda Villavicencio; Lin, Tao; Handler, Hillary P.; Dai, Yanwan; Trostle, Alexander J.; Wan, Ying-Wooi; Liu, Zhandong; V. Sillitoe, Roy; Orr, Harry T.; Zoghbi, Huda Y. 分享 收藏 Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1Coffin, Stephanie L.; Durham, Mark A.; Nitschke, Larissa; Xhako, Eder; Brown, Amanda M.; Revelli, Jean-Pierre; Gonzalez, Esmeralda Villavicencio; Lin, Tao; Handler, Hillary P.; Dai, Yanwan; Trostle, Alexander J.; Wan, Ying-Wooi; Liu, Zhandong; V. Sillitoe, Roy; Orr, Harry T.; Zoghbi, Huda Y. 分享 收藏 Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturationSun, Jialin; Osenberg, Sivan; Irwin, Austin; Ma, Li-Hu; Lee, Nigel; Xiang, Yangfei; Li, Feng; Wan, Ying-Wooi; Park, In-Hyun; Maletic-Savatic, Mirjana; Ballas, Nurit 分享 收藏 Environmental oxygen affects ex vivo growth and proliferation of mesenchymal progenitors by modulating mitogen-activated protein kinase and mammalian target of rapamycin signalingCabreira, Maria da Graca; Wang, Xiaohong; Critsinelis, Andre; Setegne, Mekedlawit; Lotfi, Parisa; Wan, Ying-Wooi; Barrios, Gabriela; Mei, Zhuyong; Gee, Adrian P.; Buja, Louis Maximilian; Perin, Emerson 分享 收藏 Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathyChen, Suet Nee; Lam, Chi Keung; Wan, Ying-Wooi; Gao, Shanshan; Malak, Olfat A.; Zhao, Shane Rui; Lombardi, Raffaella; Ambardekar, Amrut, V; Bristow, Michael R.; Cleveland, Joseph; Gigli, Marta; Sinagra, Gianfranco; Graw, Sharon; Taylor, Matthew R. G.; Wu, Joseph C.; Mestroni, Luisa 分享 收藏 Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesisOnur, Tarik Seref; Laitman, Andrew; Zhao, He; Keyho, Ryan; Kim, Hyemin; Wang, Jennifer; Mair, Megan; Wang, Huilan; Li, Lifang; Perez, Alma; de Haro, Maria; Wan, Ying-Wooi; Allen, Genevera; Lu, Boxun; Al-Ramahi, Ismael; Liu, Zhandong; Botas, Juan 分享 收藏 The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cellsBado, Igor L.; Zhang, Weijie; Hu, Jingyuan; Xu, Zhan; Wang, Hai; Sarkar, Poonam; Li, Lucian; Wan, Ying-Wooi; Liu, Jun; Wu, William; Lo, Hin Ching; Kim, Ik Sun; Singh, Swarnima; Janghorban, Mahnaz; Muscarella, Aaron M.; Goldstein, Amit; Singh, Purba; Jeong, Hyun-Hwan; Liu, Chaozhong; Schiff, Rachel; Huang, Shixia; Ellis, Matthew J.; Gaber, M. Waleed; Gugala, Zbigniew; Liu, Zhandong; Zhang, Xiang H-F 分享 收藏 Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1Lee, Won-Seok; Lavery, Laura; Rousseaux, Maxime W. C.; Rutledge, Eric B.; Jang, Youjin; Wan, Ying-Wooi; Wu, Sih-Rong; Kim, Wonho; Al-Ramahi, Ismael; Rath, Smruti; Adamski, Carolyn J.; Bondar, Vitaliy V.; Tewari, Ambika; Soleimani, Shirin; Mota, Samantha; Yalamanchili, Hari K.; Orr, Harry T.; Liu, Zhandong; Botas, Juan; Zoghbi, Huda Y. 分享 收藏 Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndromeShao, Yingyao; Sztainberg, Yehezkel; Wang, Qi; Bajikar, Sameer S.; Trostle, Alexander J.; Wan, Ying-Wooi; Jafar-Nejad, Paymaan; Rigo, Frank; Liu, Zhandong; Tang, Jianrong; Zoghbi, Huda Y. 分享 收藏 Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models阿尔茨海默病小鼠模型人脑转录组和功能解剖的Meta分析Wan, Ying-Wooi; Al-Ouran, Rami; Mangleburg, Carl G.; Perumal, Thanneer M.; Lee, Tom, V; Allison, Katherine; Swarup, Vivek; Funk, Cory C.; Gaiteri, Chris; Allen, Mariet; Wang, Minghui; Neuner, Sarah M.; Kaczorowski, Catherine C.; Philip, Vivek M.; Howell, Gareth R.; Martini-Stoica, Heidi; Zheng, Hui; Mei, Hongkang; Zhong, Xiaoyan; Kim, Jungwoo Wren; Dawson, Valina L.; Dawson, Ted M.; Pao, Ping-Chieh; Tsai, Li-Huei; Haure-Mirande, Jean-Vianney; Ehrlich, Michelle E.; Chakrabarty, Paramita; Levites, Yona; Wang, Xue; Dammer, Eric B.; Srivastava, Gyan; Mukherjee, Sumit; Sieberts, Solveig K.; Omberg, Larsson; Dang, Kristen D.; Eddy, James A.; Snyder, Phil; Chae, Yooree; Amberkar, Sandeep; Wei, Wenbin; Hide, Winston; Preuss, Christoph; Ergun, Ayla; Ebert, Phillip J.; Airey, David C.; Mostafavi, Sara; Yu, Lei; Klein, Hans-Ulrich; Carter, Gregory W.; Collier, David A.; Golde, Todd E.; Levey, Allan, I; Bennett, David A.; Estrada, Karol; Townsend, T. Matthew; Zhang, Bin; Schadt, Eric; De Jager, Philip L.; Price, Nathan D.; Ertekin-Taner, Nilufer; Liu, Zhandong; Shulman, Joshua M.; Mangravite, Lara M.; Logsdon, Benjamin A. 分享 收藏 Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndromeLavery, Laura A.; Ure, Kerstin; Wan, Ying-Wooi; Luo, Chongyuan; Trostle, Alexander J.; Wang, Wei; Jin, Haijing; Lopez, Joanna; Lucero, Jacinta; Durham, Mark A.; Castanon, Rosa; Nery, Joseph R.; Liu, Zhandong; Goodell, Margaret; Ecker, Joseph R.; Behrens, M. Margarita; Zoghbi, Huda Y. 分享 收藏 Type I interferon response drives neuroinflammation and synapse loss in Alzheimer diseaseI型干扰素反应驱动阿尔茨海默病的神经炎症和突触丢失Roy, Ethan R.; Wang, Baiping; Wan, Ying-wooi; Chiu, Gabriel; Cole, Allysa; Yin, Zhuoran; Propson, Nicholas E.; Xu, Yin; Jankowsky, Joanna L.; Liu, Zhandong; Lee, Virginia M-Y; Trojanowski, John Q.; Ginsberg, Stephen D.; Butovsky, Oleg; Zheng, Hui; Cao, Wei 分享 收藏 TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreadingMartini-Stoica, Heidi; Cole, Allysa L.; Swartzlander, Daniel B.; Chen, Fading; Wan, Ying-Wooi; Bajaj, Lakshya; Bader, David A.; Lee, Virginia M. Y.; Trojanowski, John Q.; Liu, Zhandong; Sardiello, Marco; Zheng, Hui 分享 收藏 分享 收藏 Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity大脑深部刺激诱导促进神经发生和可塑性的基因表达和剪接变化Pohodich, Amy E.; Yalamanchili, Hari; Raman, Ayush T.; Wan, Ying-Wooi; Gundry, Michael; Hao, Shuang; Jin, Haijing; Tang, Jianrong; Liu, Zhandong; Zoghbi, Huda Y. 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
