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收藏Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells组蛋白分子伴侣HIRA失活揭示了黑色素细胞前体正常胚胎发育与成体黑色素细胞干细胞维持之间的联系
Jaber-Hijazi, F; Arnold, R; Swaminathan, K; Gilroy, K; Wenzel, AT; Lagnado, A; Kirschner, K; Robertson, N; Reid, C; Fullarton, N; Pawlikowski, J; Rai, TS; Baranyk, I; Shi, CH; Yip, KY; Blyth, K; Mesirov, JP; Harris, ML; Passos, JF; Machesky, LM; Adams, PD
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收藏MULTI-OMICS AND FUNCTIONAL PRECISION MEDICINE FOR NEWLY DIAGNOSED AND RECURRENT PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS
Crawford, John R.; Lo, Yan Yuen; Pagadala, Meghana S.; Chapman, Owen S.; Sridhar, Sunita; Juarez, Edwin F.; Tzaridis, Theophilos; Chau, Lianne Q.; Wang, Jun; Eisemann, Tanja; Masihi, Meher Beigi; Chambers, Kendall R.; Dixit, Deobrat; Koubourli, Daphne; Larson, Jon D.; Guidugli, Lucia; Hammer, Monia; Wong, Terence; Abdullaev, Zied; Quezado, Martha; Martins, Timothy J.; Reich, Michael; Sears, Timothy; Hobbs, Charlotte; Kingsmore, Stephen F.; Levy, Michael L.; Gonda, David; Malicki, Denise M.; Snuderl, Matija; Becker, Pamela S.; Tamayo, Pablo; Elster, Jennifer D.; Aldape, Kenneth; Carter, Hannah; Paul, Megan R.; Mesirov, Jill P.; Chavez, Lukas; Wechsler-Reya, Robert J.
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收藏Developmental basis of SHH medulloblastoma heterogeneity
Gold, Maxwell P.; Ong, Winnie; Masteller, Andrew M.; Ghasemi, David R.; Galindo, Julie Anne; Park, Noel R.; Huynh, Nhan C.; Donde, Aneesh; Pister, Veronika; Saurez, Raul A.; Vladoiu, Maria C.; Hwang, Grace H.; Eisemann, Tanja; Donovan, Laura K.; Walker, Adam D.; Benetatos, Joseph; Dufour, Christelle; Garzia, Livia; Segal, Rosalind A.; Wechsler-Reya, Robert J.; Mesirov, Jill P.; Korshunov, Andrey; Pajtler, Kristian W.; Pomeroy, Scott L.; Ayrault, Olivier; Davidson, Shawn M.; Cotter, Jennifer A.; Taylor, Michael D.; Fraenkel, Ernest
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收藏Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS
Johnson, Jeanette A. I.; Tsang, Ashley P.; Mitchell, Jacob T.; Zhou, David L.; Bowden, Julia; Davis-Marcisak, Emily; Sherman, Thomas; Liefeld, Ted; Loth, Melanie; Goff, Loyal A.; Zimmerman, Jacquelyn W.; Kinny-Koester, Ben; Jaffee, Elizabeth M.; Tamayo, Pablo; Mesirov, Jill P.; Reich, Michael; Fertig, Elana J.; Stein-O'Brien, Genevieve L.
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收藏Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma圆形染色体外DNA促进高危髓母细胞瘤的肿瘤异质性
Chapman, Owen S.; Luebeck, Jens; Sridhar, Sunita; Wong, Ivy Tsz-Lo; Dixit, Deobrat; Wang, Shanqing; Prasad, Gino; Rajkumar, Utkrisht; Pagadala, Meghana S.; Larson, Jon D.; He, Britney Jiayu; Hung, King L.; Lange, Joshua T.; Dehkordi, Siavash R.; Chandran, Sahaana; Adam, Miriam; Morgan, Ling; Wani, Sameena; Tiwari, Ashutosh; Guccione, Caitlin; Lin, Yingxi; Dutta, Aditi; Lo, Yan Yuen; Juarez, Edwin; Robinson, James T.; Korshunov, Andrey; Michaels, John-Edward A.; Cho, Yoon-Jae; Malicki, Denise M.; Coufal, Nicole G.; Levy, Michael L.; Hobbs, Charlotte; Scheuermann, Richard H.; Crawford, John R.; Pomeroy, Scott L.; Rich, Jeremy N.; Zhang, Xinlian; Chang, Howard Y.; Dixon, Jesse R.; Bagchi, Anindya; Deshpande, Aniruddha J.; Carter, Hannah; Fraenkel, Ernest; Mischel, Paul S.; Wechsler-Reya, Robert J.; Bafna, Vineet; Mesirov, Jill P.; Chavez, Lukas
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收藏The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
Wu, Victoria H.; Yung, Bryan S.; Faraji, Farhoud; Saddawi-Konefka, Robert; Wang, Zhiyong; Wenzel, Alexander T.; Song, Miranda J.; Pagadala, Meghana S.; Clubb, Lauren M.; Chiou, Joshua; Sinha, Sanju; Matic, Marin; Raimondi, Francesco; Hoang, Thomas S.; Berdeaux, Rebecca; Vignali, Dario A. A.; Iglesias-Bartolome, Ramiro; Carter, Hannah; Ruppin, Eytan; Mesirov, Jill P.; Gutkind, J. Silvio
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收藏Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
Pagadala, Meghana; Sears, Timothy J.; Wu, Victoria H.; Perez-Guijarro, Eva; Kim, Hyo; Castro, Andrea; Talwar, James V.; Gonzalez-Colin, Cristian; Cao, Steven; Schmiedel, Benjamin J.; Goudarzi, Shervin; Kirani, Divya; Au, Jessica; Zhang, Tongwu; Landi, Teresa; Salem, Rany M.; Morris, Gerald P.; Harismendy, Olivier; Patel, Sandip Pravin; Alexandrov, Ludmil B.; Mesirov, Jill P.; Zanetti, Maurizio; Day, Chi-Ping; Fan, Chun Chieh; Thompson, Wesley K.; Merlino, Glenn; Gutkind, J. Silvio; Vijayanand, Pandurangan; Carter, Hannah
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收藏A chemogenetic approach reveals a GPCR-Gαs-PKA signaling axis promoting T cell dysfunction and cancer immunotherapy failure
Yung, Bryan S.; Wu, Victoria H.; Faraji, Farhoud; Saddawi-Konefka, Robert; Wang, Zhiyong; Wenzel, Alexander T.; Song, Miranda; Pagadala, Meghana S.; Clubb, Lauren M.; Chiou, Joshua; Sinha, Sanju; Matic, Marin; Raimondi, Francesco; Hoang, Thomas; Berdeaux, Rebecca; Vignali, Dario A.; Iglesias-Bartolome, Ramiro; Carter, Hannah; Ruppin, Eytan; Mesirov, Jill P.; Gutkind, J. Silvio
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