未登录 Compound Activity Prediction with Dose-Dependent Transcriptomic Profiles and Deep Learning Godinez, William J.; Trifonov, Vladimir; Fang, Bin; Kuzu, Guray; Pei, Luying; Guiguemde, W. Armand; Martin, Eric J.; King, Frederick J.; Jenkins, Jeremy L.; Skewes-Cox, Peter 分享 收藏
A conserved metabolic signature associated with response to fast-acting anti-malarial agents 与对速效抗疟疾药物的反应相关的保守代谢特征 Simwela, Nelson V.; Guiguemde, W. Armand; Straimer, Judith; Regnault, Clement; Stokes, Barbara H.; Tavernelli, Luis E.; Yokokawa, Fumiaki; Taft, Benjamin; Diagana, Thierry T.; Barrett, Michael P.; Waters, Andrew P. 分享 收藏
Design of potent antimalarials with generative chemistry Godinez, William J.; Ma, Eric J.; Chao, Alexander T.; Pei, Luying; Skewes-Cox, Peter; Canham, Stephen M.; Jenkins, Jeremy L.; Young, Joseph M.; Martin, Eric J.; Guiguemde, W. Armand 分享 收藏
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Van Voorhis, Wesley C.; Adams, John H.; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H.; Alano, Pietro; Alday, Aintzane; Resto, Yesmalie Aleman; Alsibaee, Aishah; Alzualde, Ainhoa; Andrews, Katherine T.; Avery, Simon V.; Avery, Vicky M.; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; Bowling, Tana; Bosch, Juergen; Boucher, Lauren E.; Boyom, Fabrice F.; Brea, Jose; Brennan, Marian; Burton, Audrey; Caffrey, Conor R.; Camarda, Grazia; Carrasquilla, Manuela; Carter, Dee; Cassera, Maria Belen; Cheng, Ken Chih-Chien; Chindaudomsate, Worathad; Chubb, Anthony; Colon, Beatrice L.; Colon-Lopez, Daisy D.; Corbett, Yolanda; Crowther, Gregory J.; Cowan, Noemi; D'Alessandro, Sarah; Le Dang, Na; Delves, Michael; DeRisi, Joseph L.; Du, Alan Y.; Duffy, Sandra; El-Sayed, Shimaa Abd El-Salam; Ferdig, Michael T.; Robledo, Jose A. Fernandez; Fidock, David A.; Florent, Isabelle; Fokou, Patrick V. T.; Galstian, Ani; Javier Gamo, Francisco; Gokool, Suzanne; Gold, Ben; Golub, Todd; Goldgof, Gregory M.; Guha, Rajarshi; Guiguemde, W. Armand; Gural, Nil; Guy, R. Kiplin; Hansen, Michael A. E.; Hanson, Kirsten K.; Hemphill, Andrew; van Huijsduijnen, Rob Hooft; Horii, Takaaki; Horrocks, Paul; Hughes, Tyler B.; Huston, Christopher; Igarashi, Ikuo; Ingram-Sieber, Katrin; Itoe, Maurice A.; Jadhav, Ajit; Jensen, Amornrat Naranuntarat; Jensen, Laran T.; Jiang, Rays H. Y.; Kaiser, Annette; Keiser, Jennifer; Ketas, Thomas; Kicka, Sebastien; Kim, Sunyoung; Kirk, Kiaran; Kumar, Vidya P.; Kyle, Dennis E.; Jose Lafuente, Maria; Landfear, Scott; Lee, Nathan; Lee, Sukjun; Lehane, Adele M.; Li, Fengwu; Little, David; Liu, Liqiong; Llinas, Manuel; Loza, Maria I.; Lubar, Aristea; Lucantoni, Leonardo; Lucet, Isabelle; Maes, Louis; Mancama, Dalu; Mansour, Nuha R.; March, Sandra; McGowan, Sheena; Vera, Iset Medina; Meister, Stephan; Mercer, Luke; Mestres, Jordi; Mfopa, Alvine N.; Misra, Raj N.; Moon, Seunghyun; Moore, John P.; Rodrigues da Costa, Francielly Morais; Mueller, Joachim; Muriana, Arantza; Hewitt, Stephen Nakazawa; Nare, Bakela; Nathan, Carl; Narraidoo, Nathalie; Nawaratna, Sujeevi; Ojo, Kayode K.; Ortiz, Diana; Panic, Gordana; Papadatos, George; Parapini, Silvia; Patra, Kailash; Ngoc Pham; Prats, Sarah; Plouffe, David M.; Poulsen, Sally-Ann; Pradhan, Anupam; Quevedo, Celia; Quinn, Ronald J.; Rice, Christopher A.; Rizk, Mohamed Abdo; Ruecker, Andrea; St Onge, Robert; Ferreira, Rafaela Salgado; Samra, Jasmeet; Robinett, Natalie G.; Schlecht, Ulrich; Schmitt, Marjorie; Villela, Filipe Silva; Silvestrini, Francesco; Sinden, Robert; Smith, Dennis A.; Soldati, Thierry; Spitzmueller, Andreas; Stamm, Serge Maximilian; Sullivan, David J.; Sullivan, William; Suresh, Sundari; Suzuki, Brian M.; Suzuki, Yo; Swamidass, S. Joshua; Taramelli, Donatella; Tchokouaha, Lauve R. Y.; Theron, Anjo; Thomas, David; Tonissen, Kathryn F.; Townson, Simon; Tripathi, Abhai K.; Trofimov, Valentin; Udenze, Kenneth O.; Ullah, Imran; Vallieres, Cindy; Vigil, Edgar; Vinetz, Joseph M.; Phat Voong Vinh; Hoan Vu; Watanabe, Nao-aki; Weatherby, Kate; White, Pamela M.; Wilks, Andrew F.; Winzeler, Elizabeth A.; Wojcik, Edward; Wree, Melanie; Wu, Wesley; Yokoyama, Naoaki; Zollo, Paul H. A.; Abla, Nada; Blasco, Benjamin; Burrows, Jeremy; Laleu, Benoit; Leroy, Didier; Spangenberg, Thomas; Wells, Timothy; Willis, Paul A. 分享 收藏
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Potent Plasmodium falciparum Gametocytocidal Activity of Diaminonaphthoquinones, Lead Antimalarial Chemotypes Identified in an Antimalarial Compound Screen Tanaka, Takeshi Q.; Guiguemde, W. Armand; Barnett, David S.; Maron, Maxim I.; Min, Jaeki; Connelly, Michele C.; Suryadevara, Praveen Kumar; Guy, R. Kiplin; Williamson, Kim C. 分享 收藏
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium Belen Jimenez-Diaz, Maria; Ebert, Daniel; Salinas, Yandira; Pradhan, Anupam; Lehane, Adele M.; Myrand-Lapierre, Marie-Eve; O'Loughlin, Kathleen G.; Shackleford, David M.; de Almeida, Mariana Justino; Carrillo, Angela K.; Clark, Julie A.; Dennis, Adelaide S. M.; Diep, Jonathon; Deng, Xiaoyan; Duffy, Sandra; Endsley, Aaron N.; Fedewa, Greg; Guiguemde, W. Armand; Gomez, Maria G.; Holbrook, Gloria; Horst, Jeremy; Kim, Charles C.; Liu, Jian; Lee, Marcus C. S.; Matheny, Amy; Santos Martinez, Maria; Miller, Gregory; Rodriguez-Alejandre, Ane; Sanz, Laura; Sigal, Martina; Spillman, Natalie J.; Stein, Philip D.; Wang, Zheng; Zhu, Fangyi; Waterson, David; Knapp, Spencer; Shelat, Anang; Avery, Vicky M.; Fidock, David A.; Gamo, Francisco-Javier; Charman, Susan A.; Mirsalis, Jon C.; Ma, Hongshen; Ferrer, Santiago; Kirk, Kiaran; Angulo-Barturen, Inigo; Kyle, Dennis E.; DeRisi, Joseph L.; Floyd, David M.; Guy, R. Kiplin 分享 收藏
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Lead Optimization of Antimalarial Propafenone Analogues Lowes, David; Pradhan, Anupam; Iyer, Lalitha V.; Parman, Toufan; Gow, Jason; Zhu, Fangyi; Furimsky, Anna; Lemoff, Andrew; Guiguemde, W. Armand; Sigal, Martina; Clark, Julie A.; Wilson, Emily; Tang, Liang; Connelly, Michele C.; DeRisi, Joseph L.; Kyle, Dennis E.; Mirsalis, Jon; Guy, R. Kiplin 分享 收藏
Lead Optimization of 3-Carboxyl-4(1H)-Quinolones to Deliver Orally Bioavailable Antimalarials Zhang, Yiqun; Clark, Julie A.; Connelly, Michele C.; Zhu, Fangyi; Min, Jaeki; Guiguemde, W. Armand; Pradhan, Anupam; Iyer, Lalitha; Furimsky, Anna; Gow, Jason; Parman, Toufan; El Mazouni, Farah; Phillips, Margaret A.; Kyle, Dennis E.; Mirsalis, Jon; Guy, R. Kiplin 分享 收藏
Optimization of Propafenone Analogues as Antimalarial Leads Lowes, David J.; Guiguemde, W. Armand; Connelly, Michele C.; Zhu, Fangyi; Sigal, Martina S.; Clark, Julie A.; Lemoff, Andrew S.; Derisi, Joseph L.; Wilson, Emily B.; Guy, R. Kiplin 分享 收藏
Synthesis and Evaluation of 7-Substituted 4-Aminoquinoline Analogues for Antimalarial Activity Hwang, Jong Yeon; Kawasuji, Takashi; Lowes, David J.; Clark, Julie A.; Connelly, Michele C.; Zhu, Fangyi; Guiguemde, W. Armand; Sigal, Martina S.; Wilson, Emily B.; DeRisi, Joseph L.; Guy, R. Kiplin 分享 收藏
Evaluation of Diarylureas for Activity Against Plasmodium falciparum Zhang, Yiqun; Anderson, Marc; Weisman, Jennifer L.; Lu, Min; Choy, Cindy J.; Boyd, Vincent A.; Price, Jeanine; Sigal, Martina; Clark, Julie; Connelly, Michele; Zhu, Fangyi; Guiguemde, W. Armand; Jeffries, Cynthia; Yang, Lei; Lemoff, Andrew; Liou, Ally P.; Webb, Thomas R.; DeRisi, Joseph L.; Guy, R. Kiplin 分享 收藏
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