未登录 Identification of highly selective SIK 1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation Babbe, Holger; Sundberg, Thomas B.; Tichenor, Mark; Seierstad, Mark; Bacani, Genesis; Berstler, James; Chai, Wenying; Chang, Leon; Chung, De Michael; Coe, Kevin; Collins, Bernard; Finley, Michael; Guletsky, Alexander; Lemke, Christopher T.; Mak, Puiying A.; Mathur, Ashok; Mercado-Marin, Eduardo, V; Metkar, Shailesh; Raymond, Donald D.; Rives, Marie -Laure; Rizzolio, Michele; Shaffer, Paul L.; Smith, Russell; Smith, Jacqueline; Steele, Ruth; Steffens, Helena; Suarez, Javier; Tian, Gaochao; Majewski, Nathan; Volak, Laurie P.; Wei, Jianmei; Desai, Prerak T.; Ong, Luvena L.; Koudriakova, Tatiana; Goldberg, Steven D.; Hirst, Gavin; Kaushik, Virendar K.; Ort, Tatiana; Seth, Nilufer; Graham, Daniel B.; Plevy, Scott; Venable, Jennifer D.; Xavier, Ramnik J.; Towne, Jennifer E. 分享 收藏
A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis Yoon, Sung-Hee; Meyer, Mark B.; Arevalo, Carlos; Tekguc, Murat; Zhang, Chengcheng; Wang, Jialiang S.; Andrade, Christian D. Castro; Strauss, Katelyn; Sato, Tadatoshi; Benkusky, Nancy A.; Lee, Seong Min; Berdeaux, Rebecca; Foretz, Marc; Sundberg, Thomas B.; Xavier, Ramnik J.; Adelmann, Charles H.; Brooks, Daniel J.; Anselmo, Anthony; Sadreyev, Ruslan I.; Rosales, Ivy A.; Fisher, David E.; Gupta, Navin; Morizane, Ryuji; Greka, Anna; Pike, J. Wesley; Mannstadt, Michael; Wein, Marc N. 分享 收藏
The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes Novel CDK8-GATA3-FOXP3 Pathway Arnett, Azlann; Moo, Keagan G.; Flynn, Kaitlin J.; Sundberg, Thomas B.; Johannessen, Liv; Shamji, Alykhan F.; Gray, Nathanael S.; Decker, Thomas; Zheng, Ye; Gersuk, Vivian H.; Rahman, Ziaur S.; Levy, David E.; Marie, Isabelle J.; Linsley, Peter S.; Xavier, Ramnik J.; Khor, Bernard 分享 收藏
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption Tang, Cheng-Chia; Andrade, Christian D. Castro; O'Meara, Maureen J.; Yoon, Sung-Hee; Sato, Tadatoshi; Brooks, Daniel J.; Bouxsein, Mary L.; Martins, Janaina da Silva; Wang, Jinhua; Gray, Nathanael S.; Misof, Barbara; Roschger, Paul; Boulin, Stephane; Klaushofer, Klaus; Velduis-Vlug, Annegreet; Vegting, Yosta; Rosen, Clifford J.; O'Connell, Daniel; Sundberg, Thomas B.; Xavier, Ramnik J.; Ung, Peter; Schlessinger, Avner; Kronenberg, Henry M.; Berdeaux, Rebecca; Foretz, Marc; Wein, Marc N. 分享 收藏
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells Johannessen, Liv; Sundberg, Thomas B.; O'Connell, Daniel J.; Kolde, Raivo; Berstler, James; Billings, Katelyn J.; Khor, Bernard; Seashore-Ludlow, Brinton; Fassl, Anne; Russell, Caitlin N.; Latorre, Isabel J.; Jiang, Baishan; Graham, Daniel B.; Perez, Jose R.; Sicinski, Piotr; Phillips, Andrew J.; Schreiber, Stuart L.; Gray, Nathanael S.; Shamji, Alykhan F.; Xavier, Ramnik J. 分享 收藏
SIKs control osteocyte responses to parathyroid hormone (vol 7, 13176, 2017) SIKs控制骨细胞对甲状旁腺激素的反应 (第7卷，13176，2017) Wein, Marc N.; Liang, Yanke; Goransson, Olga; Sundberg, Thomas B.; Wang, Jinhua; Williams, Elizabeth A.; O'Meara, Maureen J.; Govea, Nicolas; Beqo, Belinda; Nishimori, Shigeki; Nagano, Kenichi; Brooks, Daniel J.; Martins, Janaina S.; Corbin, Braden; Anselmo, Anthony; Sadreyev, Ruslan; Wu, Joy Y.; Sakamoto, Kei; Foretz, Marc; Xavier, Ramnik J.; Baron, Roland; Bouxsein, Mary L.; Gardella, Thomas J.; Divieti-Pajevic, Paola; Gray, Nathanael S.; Kronenberg, Henry M. 分享 收藏
SIKs control osteocyte responses to parathyroid hormone Wein, Marc N.; Liang, Yanke; Goransson, Olga; Sundberg, Thomas B.; Wang, Jinhua; Williams, Elizabeth A.; O'Meara, Maureen J.; Govea, Nicolas; Beqo, Belinda; Nishimori, Shigeki; Nagano, Kenichi; Brooks, Daniel J.; Martins, Janaina S.; Corbin, Braden; Anselmo, Anthony; Sadreyev, Ruslan; Wu, Joy Y.; Sakamoto, Kei; Foretz, Marc; Xavier, Ramnik J.; Baron, Roland; Bouxsein, Mary L.; Gardella, Thomas J.; Divieti-Pajevic, Paola; Gray, Nathanael S.; Kronenberg, Henry M. 分享 收藏
Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo Sundberg, Thomas B.; Liang, Yanke; Wu, Huixian; Choi, Hwan Geun; Kim, Nam Doo; Sim, Taebo; Johannessen, Liv; Petrone, Adam; Khor, Bernard; Graham, Daniel B.; Latorre, Isabel J.; Phillips, Andrew J.; Schreiber, Stuart L.; Perez, Jose; Shamji, Alykhan F.; Gray, Nathanael S.; Xavier, Ramnik J. 分享 收藏
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Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging Gustafson, Jeffrey L.; Neklesa, Taavi K.; Cox, Carly S.; Roth, Anke G.; Buckley, Dennis L.; Tae, Hyun Seop; Sundberg, Thomas B.; Stagg, D. Blake; Hines, John; McDonnell, Donald P.; Norris, John D.; Crews, Craig M. 分享 收藏
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells Khor, Bernard; Gagnon, John D.; Goel, Gautam; Roche, Marly I.; Conway, Kara L.; Tran, Khoa; Aldrich, Leslie N.; Sundberg, Thomas B.; Paterson, Alison M.; Mordecai, Scott; Dombkowski, David; Schirmer, Melanie; Tan, Pauline H.; Bhan, Atul K.; Roychoudhuri, Rahul; Restifo, Nicholas P.; O'Shea, John J.; Medoff, Benjamin D.; Shamji, Alykhan F.; Schreiber, Stuart L.; Sharpe, Arlene H.; Shaw, Stanley Y.; Xavier, Ramnik J. 分享 收藏
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Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells Sundberg, Thomas B.; Choi, Hwan Geun; Song, Joo-Hye; Russell, Caitlin N.; Hussain, Mahmud M.; Graham, Daniel B.; Khor, Bernard; Gagnon, John; O'Connell, Daniel J.; Narayan, Kavitha; Dancik, Vlado; Perez, Jose R.; Reinecker, Hans-Christian; Gray, Nathanael S.; Schreiber, Stuart L.; Xavier, Ramnik J.; Shamji, Alykhan F. 分享 收藏
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7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one(Bz-423), a benzodiazepine, suppresses keratinocyte proliferation and has antipsoriatic activity in the human skin-severe, combined Immunodeficient mouse transplant model Bhagavathula, Narasimharao; Nerusu, Kamalakar C.; Hanosh, Andrew; Aslam, Muhammad N.; Sundberg, Thomas B.; Opipari, Anthony W.; Johnson, Kent; Kang, Sewon; Glick, Gary D.; Varani, James 分享 收藏
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