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Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2 肺促血栓形成微环境中的外泌体通过整合素β2驱动肿瘤相关血栓形成和转移 Lucotti, Serena; Ogitani, Yusuke; Kanific, Candia M.; Geri, Jacob; Kim, Young Hun; Gu, Jinghua; Balaji, Uthra; Bojmar, Linda; Shaashua, Lee; Song, Yi; Cioffi, Michele; Lauritzen, Pernille; Joseph, Oveen M.; Asao, Tetsuhiko; Grandgenett, Paul M.; Hollingsworth, Michael A.; Peralta, Christopher; Pagano, Alexandra E.; Molina, Henrik; Lengel, Harry B.; Dunne, Elizabeth G.; Jing, Xiaohong; Schmitter, Madeleine; Borriello, Lucia; Miller, Thomas; Zhang, Haiying; Romin, Yevgeniy; Manova, Katia; Paul, Doru; Remmel, H. Lawrence; O'Reilly, Eileen M.; Janagin, William R.; Kelsen, David; Castellino, Sharon M.; Giulino-Roth, Lisa; Jones, David R.; Condeelis, John S.; Pascual, Virginia; Bussel, James B.; Boudreau, Nancy; Matei, Irina; Entenberg, David; Bromberg, Jacqueline F.; Simeone, Diane M.; Lyden, David 分享 收藏
Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression Wortzel, Inbal; Seo, Yura; Akano, Ife; Shaashua, Lee; Tobias, Gabriel Cardial; Hebert, Jakob; Kim, Kyung-A; Kim, Dooa; Dror, Shani; Liu, Yanshen; Azrak, Griffin Campbell; Cioffi, Michele; Johnson, Kofi Ennu; Hennika, Tammy; Twerski, Meshulam Zisha; Kushner, Alexis; Math, Robert; Han, Yoon Dae; Han, Dai Hoon; Jung, Minsun; Park, Juyeong; Paik, Soonmyung; Shin, Jeon-Soo; Lee, Min Goo; Russo, Marco Vincenzo; Zakheim, Daniel; Barnes, Jesse; Mehta, Sunjoy; Manova, Katia; Schwartz, Robert E.; Thakur, Basant Kumar; Boudreau, Nancy; Matei, Irina; Zhang, Haiying; Sidoli, Simone; Bromberg, Jacqueline; David, Yael; Kim, Han Sang; Lyden, David 分享 收藏
MAP kinase kinase 1 (MEK1) within extracellular vesicles inhibits tumour growth by promoting anti-tumour immunity Searles, Stephen C.; Chen, Wei-Shan; Yee, Jarrod D.; Lee, Preston; Lee, Calvin K.; Caron, Christine; Neto, Felippe; Matei, Irina; Lyden, David; Bui, Jack D. 分享 收藏
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer Bojmar, Linda; Zambirinis, Constantinos P.; Hernandez, Jonathan M.; Chakraborty, Jayasree; Shaashua, Lee; Kim, Junbum; Johnson, Kofi Ennu; Hanna, Samer; Askan, Gokce; Burman, Jonas; Ravichandran, Hiranmayi; Zheng, Jian; Jolissaint, Joshua S.; Srouji, Rami; Song, Yi; Choubey, Ankur; Kim, Han Sang; Cioffi, Michele; van Beek, Elke; Sigel, Carlie; Jessurun, Jose; Velasco Riestra, Paulina; Blomstrand, Hakon; Joensson, Carolin; Joensson, Anette; Lauritzen, Pernille; Buehring, Weston; Ararso, Yonathan; Hernandez, Dylanne; Vinagolu-Baur, Jessica P.; Friedman, Madison; Glidden, Caroline; Firmenich, Laetitia; Lieberman, Grace; Mejia, Dianna L.; Nasar, Naaz; Mutvei, Anders P.; Paul, Doru M.; Bram, Yaron; Costa-Silva, Bruno; Basturk, Olca; Boudreau, Nancy; Zhang, Haiying; Matei, Irina R.; Hoshino, Ayuko; Kelsen, David; Sagi, Irit; Scherz, Avigdor; Scherz-Shouval, Ruth; Yarden, Yosef; Oren, Moshe; Egeblad, Mikala; Lewis, Jason S.; Keshari, Kayvan; Grandgenett, Paul M.; Hollingsworth, Michael A.; Rajasekhar, Vinagolu K.; Healey, John H.; Bjoernsson, Bergthor; Simeone, Diane M.; Tuveson, David A.; Iacobuzio-Donahue, Christine A.; Bromberg, Jaqueline; Vincent, C. Theresa; O'Reilly, Eileen M.; DeMatteo, Ronald P.; Balachandran, Vinod P.; D'Angelica, Michael I.; Kingham, T. Peter; Allen, Peter J.; Simpson, Amber L.; Elemento, Olivier; Sandstroem, Per; Schwartz, Robert E.; Jarnagin, William R.; Lyden, David 分享 收藏
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight Kim, JangKeun; Tierney, Braden T.; Overbey, Eliah G.; Dantas, Ezequiel; Fuentealba, Matias; Park, Jiwoon; Narayanan, S. Anand; Wu, Fei; Najjar, Deena; Chin, Christopher R.; Meydan, Cem; Loy, Conor; Mathyk, Begum; Klotz, Remi; Ortiz, Veronica; Nguyen, Khiem; Ryon, Krista A.; Damle, Namita; Houerbi, Nadia; Patras, Laura I.; Schanzer, Nathan; Hutchinson, Gwyneth A.; Foox, Jonathan; Bhattacharya, Chandrima; Mackay, Matthew; Afshin, Evan E.; Hirschberg, Jeremy Wain; Kleinman, Ashley S.; Schmidt, Julian C.; Schmidt, Caleb M.; Schmidt, Michael A.; Beheshti, Afshin; Matei, Irina; Lyden, David; Mullane, Sean; Asadi, Amran; Lenz, Joan S.; Mzava, Omary; Yu, Min; Ganesan, Saravanan; De Vlaminck, Iwijn; Melnick, Ari M.; Barisic, Darko; Winer, Daniel A.; Zwart, Sara R.; Crucian, Brian E.; Smith, Scott M.; Mateus, Jaime; Furman, David; Mason, Christopher E. 分享 收藏
Cosmic kidney disease: an integrated panomic, physiological andmorphological study into spaceflight-induced renal dysfunction 宇宙肾脏疾病: 对太空飞行引起的肾功能不全的综合，生理和形态学研究 Siew, Keith; Nestler, Kevin A.; Nelson, Charlotte; D'Ambrosio, Viola; Zhong, Chutong; Li, Zhongwang; Grillo, Alessandra; Wan, Elizabeth R.; Patel, Vaksha; Overbey, Eliah; Kim, JangKeun; Yun, Sanghee; Vaughan, Michael B.; Cheshire, Chris; Cubitt, Laura; Broni-Tabi, Jessica; Al-Jaber, Maneera Yousef; Boyko, Valery; Meydan, Cem; Barker, Peter; Arif, Shehbeel; Afsari, Fatemeh; Allen, Noah; Al-Maadheed, Mohammed; Altinok, Selin; Bah, Nourdine; Border, Samuel; Brown, Amanda L.; Burling, Keith; Cheng-Campbell, Margareth; Colon, Lorianna M.; Degoricija, Lovorka; Figg, Nichola; Finch, Rebecca; Foox, Jonathan; Faridi, Pouya; French, Alison; Gebre, Samrawit; Gordon, Peter; Houerbi, Nadia; Kahrood, Hossein Valipour; Kiffer, Frederico C.; Klosinska, Aleksandra S.; Kubik, Angela; Lee, Han-Chung; Li, Yinghui; Lucarelli, Nicholas; Marullo, Anthony L.; Matei, Irina; McCann, Colleen M.; Mimar, Sayat; Naglah, Ahmed; Nicod, Jerome; O'Shaughnessy, Kevin M.; De Oliveira, Lorraine Christine; Oswalt, Leah; Patras, Laura Ioana; Polo, San-Huei Lai; Rodriguez-Lopez, Maria; Roufosse, Candice; Sadeghi-Alavijeh, Omid; Sanchez-Hodge, Rebekah; Paul, Anindya S.; Schittenhelm, Ralf Bernd; Schweickart, Annalise; Scott, Ryan T.; Sian, Terry Chin Choy Lim Kam; da Silveira, Willian A.; Slawinski, Hubert; Snell, Daniel; Sosa, Julio; Saravia-Butler, Amanda M.; Tabetah, Marshall; Tanuwidjaya, Erwin; Walker-Samuel, Simon; Yang, Xiaoping; Yasmin; Zhang, Haijian; Godovac-Zimmermann, Jasminka; Sarder, Pinaki; Sanders, Lauren M.; Costes, Sylvain V.; Campbell, Robert A. A.; Karouia, Fathi; Mohamed-Alis, Vidya; Rodriques, Samuel; Lynham, Steven; Steele, Joel Ricky; Baranzini, Sergio; Fazelinia, Hossein; Dai, Zhongquan; Uruno, Akira; Shiba, Dai; Yamamoto, Masayuki; Almeida, Eduardo A. C.; Blaber, Elizabeth; Schisler, Jonathan C.; Eisch, Amelia J.; Muratani, Masafumi; Zwart, Sara R.; Smith, Scott M.; Galazka, Jonathan M.; Mason, Christopher E.; Beheshti, Afshin; Walsh, Stephen B. 分享 收藏
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew Jones, Christopher W.; Overbey, Eliah G.; Lacombe, Jerome; Ecker, Adrian J.; Meydan, Cem; Ryon, Krista; Tierney, Braden; Damle, Namita; Mackay, Matthew; Afshin, Evan E.; Foox, Jonathan; Park, Jiwoon; Nelson, Theodore M.; Mohamad, Mir Suhail; Byhaqui, Syed Gufran Ahmad; Aslam, Burhan; Tali, Ummer Akbar; Nisa, Liaqun; Menon, Priya V.; Patel, Chintan O.; Khan, Sharib A.; Ebert, Doug J.; Everson, Aaron; Schubert, Michael C.; Ali, Nabila N.; Sarma, Mallika S.; Kim, Jangkeun; Houerbi, Nadia; Grigorev, Kirill; Medina, J. Sebastian Garcia; Summers, Alexander J.; Gu, Jian; Altin, John A.; Fattahi, Ali; Hirzallah, Mohammad I.; Wu, Jimmy H.; Stahn, Alexander C.; Beheshti, Afshin; Klotz, Remi; Ortiz, Veronica; Yu, Min; Patras, Laura; Matei, Irina; Lyden, David; Melnick, Ari; Banerjee, Neil; Mullane, Sean; Kleinman, Ashley S.; Loesche, Michael; Menon, Anil S.; Donoviel, Dorit B.; Urquieta, Emmanuel; Mateus, Jaime; Sargsyan, Ashot E.; Shelhamer, Mark; Zenhausern, Frederic; Bershad, Eric M.; Basner, Mathias; Mason, Christopher E. 分享 收藏
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA) Overbey, Eliah G.; Ryon, Krista; Kim, Jangkeun; Tierney, Braden T.; Klotz, Remi; Ortiz, Veronica; Mullane, Sean; Schmidt, Julian C.; Mackay, Matthew; Damle, Namita; Najjar, Deena; Matei, Irina; Patras, Laura; Medina, J. Sebastian Garcia; Kleinman, Ashley S.; Hirschberg, Jeremy Wain; Proszynski, Jacqueline; Narayanan, S. Anand; Schmidt, Caleb M.; Afshin, Evan E.; Innes, Lucinda; Saldarriaga, Mateo Mejia; Schmidt, Michael A.; Granstein, Richard D.; Shirah, Bader; Yu, Min; Lyden, David; Mateus, Jaime; Mason, Christopher E. 分享 收藏
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight Houerbi, Nadia; Kim, Jangkeun; Overbey, Eliah G.; Batra, Richa; Schweickart, Annalise; Patras, Laura; Lucotti, Serena; Ryon, Krista A.; Najjar, Deena; Meydan, Cem; Damle, Namita; Chin, Christopher; Narayanan, S. Anand; Guarnieri, Joseph W.; Widjaja, Gabrielle; Beheshti, Afshin; Tobias, Gabriel; Vatter, Fanny; Hirschberg, Jeremy Wain; Kleinman, Ashley; Afshin, Evan E.; Mackay, Matthew; Chen, Qiuying; Miller, Dawson; Gajadhar, Aaron S.; Williamson, Lucy; Tandel, Purvi; Yang, Qiu; Chu, Jessica; Benz, Ryan; Siddiqui, Asim; Hornburg, Daniel; Gross, Steven; Shirah, Bader; Krumsiek, Jan; Mateus, Jaime; Mao, Xiao; Matei, Irina; Mason, Christopher E. 分享 收藏
Spatiotemporal expression and control of haemoglobin in space Borg, Josef; Loy, Conor; Kim, Jangkeun; Buhagiar, Alfred; Chin, Christopher; Damle, Namita; De Vlaminck, Iwijn; Felice, Alex; Liu, Tammy; Matei, Irina; Meydan, Cem; Muratani, Masafumi; Mzava, Omary; Overbey, Eliah; Ryon, Krista A.; Smith, Scott M.; Tierney, Braden T.; Trudel, Guy; Zwart, Sara R.; Beheshti, Afshin; Mason, Christopher E.; Borg, Joseph 分享 收藏
Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load Nanaware, Padma P.; Khan, Zohaib N.; Clement, Cristina C.; Shetty, Madhur; Mota, Ines; Seltzer, Ethan S.; Dzieciatkowska, Monika; Gamboni, Fabia; D'Alessandro, Angelo; Ng, Charles; Nagayama, Manabu; Lichti, Cheryl F.; Soni, Rajesh K.; Geri, Jacob B.; Matei, Irina; Lyden, David; Longman, Randy; Lu, Theresa T.; Wan, Xiaoxiao; Unanue, Emil R.; Stern, Lawrence J.; Santambrogio, Laura 分享 收藏
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight Garcia-Medina, J. Sebastian; Sienkiewicz, Karolina; Narayanan, S. Anand; Overbey, Eliah G.; Grigorev, Kirill; Ryon, Krista A.; Burke, Marissa; Proszynski, Jacqueline; Tierney, Braden; Schmidt, Caleb M.; Mencia-Trinchant, Nuria; Klotz, Remi; Ortiz, Veronica; Foox, Jonathan; Chin, Christopher; Najjar, Deena; Matei, Irina; Chan, Irenaeus; Cruchaga, Carlos; Kleinman, Ashley; Kim, Jangkeun; Lucaci, Alexander; Loy, Conor; Mzava, Omary; De Vlaminck, Iwijn; Singaraju, Anvita; Taylor, Lynn E.; Schmidt, Julian C.; Schmidt, Michael A.; Blease, Kelly; Moreno, Juan; Boddicker, Andrew; Zhao, Junhua; Lajoie, Bryan; Altomare, Andrew; Kruglyak, Semyon; Levy, Shawn; Yu, Min; Hassane, Duane C.; Bailey, Susan M.; Bolton, Kelly; Mateus, Jaime; Mason, Christopher E. 分享 收藏
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Perioperative liver biopsy captures features of the liver pre-metastatic niche and predicts metastatic outcome after pancreatic cancer resection Bojmar, Linda; Zambirinis, Constantinos P.; Hernandez, Jonathan; Chakraborty, Jayasree; Hanna, Samer; Simeone, Diane; Kelsen, David; Zhang, Haiying; Matei, Irina R.; Sandstrom, Per; Schwartz, Robert; Jarnagin, William R.; Lyden, David 分享 收藏
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Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection Brown, Julia A.; Sanidad, Katherine Z.; Lucotti, Serena; Lieber, Carolin M.; Cox, Robert M.; Ananthanarayanan, Aparna; Basu, Srijani; Chen, Justin; Shan, Mengrou; Amir, Mohammed; Schmidt, Fabian; Weisblum, Yiska; Cioffi, Michele; Li, Tingting; Rowdo, Florencia Madorsky; Martin, M. Laura; Guo, Chun-Jun; Lyssiotis, Costas; Layden, Brian T.; Dannenberg, Andrew J.; Bieniasz, Paul D.; Lee, Benhur; Inohara, Naohiro; Matei, Irina; Plemper, Richard K.; Zeng, Melody Y. 分享 收藏
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