未登录Paediatric meningitis in the conjugate vaccine era and a novel clinical decision model to predict bacterial aetiology
Martin, N. G.; Defres, S.; Willis, L.; Beckley, R.; Hardwick, H.; Coxon, A.; Kadambari, S.; Yu, L. -M.; Liu, X.; Galal, U.; Conlin, K.; Griffiths, M. J.; Kneen, R.; Nadel, S.; Heath, P. T.; Kelly, D. E.; Solomon, T.; Sadarangani, M.; Pollard, A. J. .png)
分享.png)
收藏KRAS inhibition triggers coordinated neoplastic and immune remodeling in the tumor microenvironmentLu, Daniel; Osgood, Tao; Ma, Shining; Estrada, Juan; Arias, Vanessa; Yamawaki, Tracy; Hoang, Uyen; Rex, Karen; Devoss, Jason; Canon, Jude; Lipford, Rusty; Wang, Songli; Coxon, Angela; Li, Chi-Ming 分享 收藏 Unveiling diverse trimeric forms of STEAP1 in human prostate cancer cells: Exploring STEAP1-STEAP2 interdependence for expression and plasma membrane localizationLi, Cong; Liang, Lingming; Park, Joonhee; Pryshchep, Olga; Staley, Binnaz; Li, Peng; Alba, Ben; Liu, Xuan; Li, Fei; Moore, Gregory L.; Bernett, Matthew J.; Muchhal, Umesh; Desjarlais, John; Coxon, Angela; Bailis, Julie M. 分享 收藏 Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancersPayton, Marc; Belmontes, Brian; Hanestad, Kelly; Moriguchi, Jodi; Chen, Kui; Mccarter, John D.; Chung, Grace; Ninniri, Maria Stefania; Sun, Jan; Manoukian, Raffi; Chambers, Stuart; Ho, Seok-Man; Kurzeja, Robert J. M.; Edson, Katheryne Z.; Dahal, Upendra P.; Wu, Tian; Wannberg, Sharon; Beltran, Pedro J.; Canon, Jude; Boghossian, Andrew S.; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Minocherhomji, Sheroy; Bourbeau, Matthew P.; Allen, Jennifer R.; Coxon, Angela; Tamayo, Nuria A.; Hughes, Paul E. 分享 收藏 Preclinical Assessment of a MUC12-Targeted BiTE (Bispecific T-cell Engager) MoleculePham, Elizabeth; Friedrich, Matthias; Aeffner, Famke; Lutteropp, Michael; Mariano, Natalie F.; Deegen, Petra; Dahlhoff, Christoph; Vogel, Franziska; Bluemel, Claudia; Harrold, John M.; Brandl, Christian; Grinberg, Natalia; Rattel, Benno; Coxon, Angela; Bailis, Julie M. 分享 收藏 AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeysGoldstein, Rebecca L.; Goyos, Ana; Li, Chi-Ming; Deegen, Petra; Bogner, Pamela; Sternjak, Alexander; Thomas, Oliver; Klinger, Matthias; Wahl, Joachim; Friedrich, Matthias; Rattel, Benno; Lamas, Edwin; Min, Xiaoshan; Sudom, Athena; Farshbaf, Mozhgan; Coxon, Angela; Balazs, Mercedesz; Arvedson, Tara 分享 收藏 Characterization of a Novel FLT3 BITE Molecule for the Treatment of Acute Myeloid LeukemiaBrauchle, Bettina; Goldstein, Rebecca L.; Karbowski, Christine M.; Henn, Anja; Li, Chi-Ming; Buecklein, Veit L.; Krupka, Christina; Boyle, Michael C.; Koppikar, Priya; Haubner, Sascha; Wahl, Joachim; Dahlhoff, Christoph; Raum, Tobias; Rardin, Matthew J.; Sastri, Christine; Rock, Dan A.; Von Bergwelt-Baildon, Michael; Frank, Brendon; Metzeler, Klaus H.; Case, Ryan; Friedrich, Matthias; Balazs, Mercedesz; Spiekermann, Karsten; Coxon, Angela; Subklewe, Marion; Arvedson, Tara 分享 收藏 Antitumor activity of AMG757, a half-life extended (HLE) bispecific T-cell engager (BiTE®) immune therapy targeting DLL3, in human PDX and orthotopic mouse models of small cell lung cancer (SCLC)Cooke, Keegan; Estrada, Juan; Zhan, Jinghui; Werner, Jonathan; Caenepeel, Sean; Giffin, Mike; Bailis, Julie M.; Coxon, Angela; Hughes, Paul E.; Canon, Jude 分享 收藏 Preclinical evaluation of BiTE®immune therapy targeting MUC17 or CLDN18.2 for gastric cancerBailis, Julie M.; Lutterbuese, Petra; Thomas, Oliver; Locher, Kathrin; Harrold, John; Boyle, Michael; Wahl, Joachim; Li, Shyun; Sternjak, Alexander; Henn, Anja; Dahlhoff, Christoph; Naegele, Virginie; Rattel, Benno; Raum, Tobias; Coxon, Angela 分享 收藏 Discovery and preclinical evaluation of AMG 397, a potent, selective and orally bioavailable MCL1 inhibitorCaenepeel, Sean; Karen, Rex; Belmontes, Brian; Verlinsky, Alla; Tan, Hong; Yang, Yajing; Chen, Xiaoyue; Li, Kexue; Allen, Jennifer; Wahlstrom, Jan; Canon, Jude; Coxon, Angela; Hughes, Paul 分享 收藏 Dual Inhibition of Angiopoietin-TIE2 and MET Alters the Tumor Microenvironment and Prolongs Survival in a Metastatic Model of Renal Cell CarcinomaElbanna, May; Orillion, Ashley R.; Damayanti, Nur P.; Adelaiye-Ogala, Remi; Shen, Li; Miles, Kiersten Marie; Chintala, Sreenivasulu; Ciamporcero, Eric; Ramakrishnan, Swathi; Ku, Sheng-yu; Rex, Karen; Caenepeel, Sean; Coxon, Angela; Pili, Roberto 分享 收藏 分享 收藏 Exploiting MCL1 Dependency with Combination MEK+MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non-Small Cell Lung CancerNangia, Varuna; Siddiqui, Faria M.; Caeriepeel, Sean; Timonina, Daria; Bilton, Samantha J.; Phan, Nicole; Gomez-Caraballo, Maria; Archibald, Hannah L.; Li, Chendi; Fraser, Cameron; Rigas, Diamanda; Vajda, Kristof; Ferris, Lorin A.; Lanuti, Michael; Wright, Cameron D.; Raskin, Kevin A.; Cahill, Daniel P.; Shin, John H.; Keyes, Colleen; Sequist, Lecia, V; Piotrowska, Zofia; Farago, Anna F.; Azzoli, Christopher G.; Gainor, Justin F.; Sarosiek, Kristopher A.; Brown, Sean P.; Coxon, Angela; Benes, Cyril H.; Hughes, Paul E.; Hata, Aaron N. 分享 收藏 AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established TherapiesCaenepeel, Sean; Brown, Sean P.; Belmontes, Brian; Moody, Gordon; Keegan, Kathleen S.; Chui, Danny; Whittington, Douglas A.; Huang, Xin; Poppe, Leszek; Cheng, Alan C.; Cardozom, Mario; Houze, Jonathan; Li, Yunxiao; Lucas, Brian; Paras, Nick A.; Wang, Xianghong; Taygerly, Joshua P.; Vimolratana, Marc; Zancanella, Manuel; Zhu, Liusheng; Cajulis, Elaina; Osgood, Tao; Sun, Jan; Damon, Leah; Egan, Regina K.; Greninger, Patricia; McClanaghan, Joseph D.; Gong, Jianan; Moujalled, Donia; Pomilio, Giovanna; Beltran, Pedro; Benes, Cyril H.; Roberts, Andrew W.; Huang, David C.; Wei, Andrew; Canon, Jude; Coxon, Angela; Hughes, Paul E. 分享 收藏 分享 收藏 Cynomolgus monkey plasma cell gene signature to quantify the in vivoactivity of a half-life extended anti-BCMA BiTE® for the treatment of multiple myelomaGoyos, Ana; Li, Chi-Ming; Deegen, Petra; Bogner, Pamela; Thomas, Oliver; Wahl, Joachim; Goldstein, Rebecca; Friedrich, Maththias; Coxon, Angela; Balazs, Mercedesz; Arvedson, Tara 分享 收藏 Generation and evaluation of an FLT3 CAR-T cell therapy for the treatment of acute myeloid leukemiaBakker, Alice; Lebrec, Herve; Lindl, Bettina; Adams, Gregor; Mardiros, Armen; Koppikar, Priya; Li, Chi Ming; Gong, Mei; Zheng, Yan; Sastri, Christine; Balazs, Mercedesz; Goldstein, Rebecca; Rock, Dan; Wu, Lawren; Polverino, Anthony; Subklewe, Marion; Coxon, Angela; Arvedson, Tara 分享 收藏 分享 收藏 分享 收藏 High-throughput small-molecule and RNAi screens identify Aurora kinase B inhibitors as a novel treatment for Merkel cell carcinomaGelb, T.; Urban, D.; Coxon, A.; Gryder, B.; Xiao, Y.; Glavin, R.; Chakka, S.; Lee, O.; Shen, M.; Lal-Nag, M.; Hall, M.; Brownell, I. 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
