Claudio O. Fernández - Publications, H-index & Citations

Claudio O. Fernández

universidad nacional de rosario

41H指数

118论文数

6.5K被引数

收录论文 51

发表时间

Structural biology of alpha-synuclein amyloid ﬁlaments: Implications in synucleinopathies α-突触核蛋白淀粉样纤维的结构生物学：在突触核蛋白病中的意义

Journal of Parkinsons Disease

IF5

2026-06-19

PREAI

Phelippe do Carmo Gonçalves; Irina Fernández; Claudio O. Fernández Outón

A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features 一种新型的α-突触核蛋白G14R错义变体与不典型神经病理特征相关联

Molecular Neurodegeneration

IF17.5

2025-09-28

OAAI

Christof Brücke; Mohammed Al-Azzani; Nagendran Ramalingam; Maria Ramón; Rita L. Sousa; Fiamma Buratti; Michael Zech; Kevin Sicking; Leslie Amaral; Ellen Gelpi; Aswathy Chandran; Aishwarya Agarwal; Susana R. Chaves; Claudio O. Fernández; Ulf Dettmer; Janin Lautenschläger; Markus Zweckstetter; Ruben Fernandez Busnadiego; Alexander Zimprich; Tiago Fleming Outeiro

A Novel α-Synuclein K58N Missense Variant in a Patient with Parkinson's Disease 一种新型α-突触核蛋白K58N错义变异在一名帕金森病患者中的发现

Movement Disorders

IF7.6

2025-09-04

OAAI

Mohammed Al-Azzani PhD; Sandrina Weber MD; Nagendran Ramalingam PhD; Maria Ramón MSc; Liana Shvachiy PhD; Gonçalo Mestre MSc; Michael Zech MD; Kevin Sicking PhD; Alain Ibáñez de Opakua PhD; Vidyashree Jayanthi BSc; Leslie Amaral PhD; Aishwarya Agarwal PhD; Aswathy Chandran PhD; Susana R. Chaves PhD; Juliane Winkelmann MD; Claudia Trenkwalder MD; Maike Schwager MSc; Silke Pauli PhD; Ulf Dettmer PhD; Claudio O. Fernández PhD; Janin Lautenschläger PhD; Markus Zweckstetter PhD; Ruben Fernandez Busnadiego PhD; Brit Mollenhauer MD; Tiago Fleming Outeiro PhD

Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-10-28

OAAI

de Bruyn, Emile; Dorn, Anton Emil; Rossetti, Giulia; Fernandez, Claudio; Outeiro, Tiago F.; Schulz, Joerg B.; Carloni, Paolo

Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents

ACS OMEGA

IF4.3

2023-07-13

OAAI

Bruna-Haupt, Ezequiel F.; Perretti, Marcelle D.; Garro, Hugo A.; Carrillo, Romen; Machin, Felix; Lorenzo-Castrillejo, Isabel; Gutierrez, Lucas; Vega-Hissi, Esteban G.; Mamberto, Macarena; Menacho-Marquez, Mauricio; Fernandez, Claudio O.; Garcia, Celina; Pungitore, Carlos R.

New mescaline-related N-acylhydrazone and its unsubstituted benzoyl derivative: Promising metallophores for copper-associated deleterious effects relief in Alzheimer's disease

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2023-01-01

PREAI

Carvalho, Alessandra; Barbosa, Barbara Marinho; Flores, Jesica S.; do Carmo Goncalves, Phelippe; Diniz, Renata; Cordeiro, Yraima; Fernandez, Claudio O.; Cukierman, Daphne S.; Rey, Nicolas A.

Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts

NATURE COMMUNICATIONS

IF15.7

2019-12-04

147

OAAI

Strohaeker, Timo; Jung, Byung Chul; Liou, Shu-Hao; Fernandez, Claudio O.; Riedel, Dietmar; Becker, Stefan; Halliday, Glenda M.; Bennati, Marina; Kim, Woojin S.; Lee, Seung-Jae; Zweckstetter, Markus

Binucleating Hydrazonic Ligands and Their μ-Hydroxodicopper(II) Complexes as Promising Structural Motifs for Enhanced Antitumor Activity

INORGANIC CHEMISTRY

IF4.7

2019-06-17

PREAI

Rada, Jesica Paola; Bastos, Beatriz S. M.; Anselmino, Luciano; Franco, Chris H. J.; Lanznaster, Mauricio; Diniz, Renata; Fernandez, Claudio O.; Menacho-Marquez, Mauricio; Percebom, Ana Maria; Rey, Nicolas A.

Membrane binding, internalization, and sorting of alpha-synuclein in the cell

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2018-08-14

OAAI

Masaracchia, Caterina; Hnida, Marilena; Gerhardt, Ellen; da Fonseca, Tomas Lopes; Villar-Pique, Anna; Branco, Tiago; Stahlberg, Markus A.; Dean, Camin; Fernandez, Claudio O.; Milosevic, Ira; Outeiro, Tiago F.

Small-Molecule-Induced Soluble Oligomers of α-Synuclein with Helical Structure

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2017-08-23

PREAI

Fonseca-Ornelas, Luis; Schmidt, Carla; Camacho-Zarco, Aldo R.; Fernandez, Claudio O.; Becker, Stefan; Zweckstetter, Markus

Bioinorganic Chemistry of Parkinson's Disease: Affinity and Structural Features of Cu(I) Binding to the Full-Length β-Synuclein Protein

INORGANIC CHEMISTRY

IF4.7

2017-08-18

OAAI

Miotto, Marco C.; Pavese, Mayra D.; Quintanar, Liliana; Zweckstetter, Markus; Griesinger, Christian; Fernandez, Claudio O.

A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2017-05-01

OAAI

Cukierman, Daphne Schneider; Pinheiro, Ana Beatriz; Castineiras-Filho, Sergio L. P.; da Silva, Anastacia Sa P.; Miotto, Marco C.; De Falco, Anna; Ribeiro, Thales de P.; Maisonette, Silvia; da Cunha, Alessandra L. M. C.; Hauser-Davis, Rachel A.; Landeira-Fernandez, J.; Aucelio, Ricardo Q.; Outeiro, Tiago F.; Pereira, Marcos D.; Fernandez, Claudio O.; Rey, Nicolas A.

Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-oxic parallel beta-sheet structured species

SCIENTIFIC REPORTS

IF3.9

2017-02-03

OAAI

Gonzalez-Lizarraga, Florencia; Socias, Sergio B.; Avila, Cesar L.; Torres-Bugeau, Clarisa M.; Barbosa, Leandro R. S.; Binolfi, Andres; Sepulveda-Diaz, Julia E.; Del-Bel, Elaine; Fernandez, Claudio O.; Papy-Garcia, Dulce; Itri, Rosangela; Raisman-Vozari, Rita; Chehin, Rosana N.

Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-10-05

OAAI

Villar-Pique, Anna; da Fonseca, Tomas Lopes; Sant'Anna, Ricardo; Szegoe, Eva Monika; Fonseca-Ornelas, Luis; Pinho, Raquel; Carija, Anita; Gerhardt, Ellen; Masaracchia, Caterina; Gonzalez, Enrique Abad; Rossetti, Giulia; Carloni, Paolo; Fernandez, Claudio O.; Foguel, Debora; Milosevic, Ira; Zweckstetter, Markus; Ventura, Salvador; Outeiro, Tiago Fleming

Copper Coordination Features of Human Islet Amyloid Polypeptide: The Type 2 Diabetes Peptide

INORGANIC CHEMISTRY

IF4.7

2016-10-05

OAAI

Sanchez-Lopez, Carolina; Cortes-Mejia, Rodrigo; Miotto, Marco C.; Binolfi, Andres; Fernandez, Claudio O.; del Campo, Jorge M.; Quintanar, Liliana

Phthalocyanines as Molecular Scaffolds to Block Disease-Associated Protein Aggregation

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2016-05-02

OAAI

Valiente-Gabioud, Ariel A.; Miotto, Marco C.; Chesta, Maria E.; Lombardo, Veronica; Binolfi, Andres; Fernandez, Claudio O.

Spectroscopic and Theoretical Study of CuI Binding to His111 in the Human Prion Protein Fragment 106-115

INORGANIC CHEMISTRY

IF4.7

2016-03-01

OAAI

Arcos-Lopez, Trinidad; Qayyum, Munzarin; Rivillas-Acevedo, Lina; Miotto, Marco C.; Grande-Aztatzi, Rafael; Fernandez, Claudio O.; Hedman, Britt; Hodgson, Keith O.; Vela, Alberto; Solomon, Edward I.; Quintanar, Liliana

Copper Binding to the N-Terminally Acetylated, Naturally Occurring Form of Alpha-Synuclein Induces Local Helical Folding

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2015-05-15

OAAI

Miotto, Marco C.; Valiente-Gabioud, Ariel A.; Rossetti, Giulia; Zweckstetter, Markus; Carloni, Paolo; Selenko, Philipp; Griesinger, Christian; Binolfi, Andres; Fernandez, Claudio O.

Small molecule-mediated stabilization of vesicle-associated helical α-synuclein inhibits pathogenic misfolding and aggregation

NATURE COMMUNICATIONS

IF15.7

2014-12-19

OAAI

Fonseca-Ornelas, Luis; Eisbach, Sybille E.; Paulat, Maria; Giller, Karin; Fernandez, Claudio O.; Outeiro, Tiago F.; Becker, Stefan; Zweckstetter, Markus

Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions 突触核蛋白病的生物无机化学: 破译Met基序和His-50在AS-Cu(I) 相互作用中的结合特征

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2014-12-01

OAAI

Miotto, Marco C.; Binolfi, Andres; Zweckstetter, Markus; Griesinger, Christian; Fernandez, Claudio O.

研究方向