Markus Zweckstetter - Publications, H-index & Citations

Markus Zweckstetter

german center for neurodegenerative diseases

90H指数

429论文数

2.8W被引数

收录论文 196

发表时间

IFI16 restricts SARS-CoV-2 replication by disrupting nucleocapsid-driven phase separation IFI16通过破坏核衣壳驱动的相分离来限制SARS-CoV-2的复制

Communications Biology

IF5.1

2026-06-01

OAAI

Ilaria Cislaghi; Sarah Turati; Dalila Vicario; Gloria Griffante; Shikha Chandel; Irene Lo Cigno; Ranieri Bizzarri; Barbara Storti; Tina Ukmar Godec; Milan Zachrdla; Markus Zweckstetter; Lucia Signorini; Kevin Kamau Maina; Serena Delbue; Cinzia Borgogna; Marisa Gariglio

Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation 敲除与LRRK2拮抗的RAB磷酸酶PPM1H破坏轴突自噬并加剧α-突触核蛋白聚集

Cell Reports

IF6.9

2026-05-21

OAAI

Michel Fricke; Anna Mechel; Lennart Evers; Björn Twellsieck; Jessica M. Grein; Maria-Sol Cima-Omori; Mohammed Al-Azzani; Tiago F. Outeiro; Markus Zweckstetter; Erika L.F. Holzbaur; C. Alexander Boecker

A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features 一种新型的α-突触核蛋白G14R错义变体与不典型神经病理特征相关联

Molecular Neurodegeneration

IF17.5

2025-09-28

OAAI

Christof Brücke; Mohammed Al-Azzani; Nagendran Ramalingam; Maria Ramón; Rita L. Sousa; Fiamma Buratti; Michael Zech; Kevin Sicking; Leslie Amaral; Ellen Gelpi; Aswathy Chandran; Aishwarya Agarwal; Susana R. Chaves; Claudio O. Fernández; Ulf Dettmer; Janin Lautenschläger; Markus Zweckstetter; Ruben Fernandez Busnadiego; Alexander Zimprich; Tiago Fleming Outeiro

A Novel α-Synuclein K58N Missense Variant in a Patient with Parkinson's Disease 一种新型α-突触核蛋白K58N错义变异在一名帕金森病患者中的发现

Movement Disorders

IF7.6

2025-09-04

OAAI

Mohammed Al-Azzani PhD; Sandrina Weber MD; Nagendran Ramalingam PhD; Maria Ramón MSc; Liana Shvachiy PhD; Gonçalo Mestre MSc; Michael Zech MD; Kevin Sicking PhD; Alain Ibáñez de Opakua PhD; Vidyashree Jayanthi BSc; Leslie Amaral PhD; Aishwarya Agarwal PhD; Aswathy Chandran PhD; Susana R. Chaves PhD; Juliane Winkelmann MD; Claudia Trenkwalder MD; Maike Schwager MSc; Silke Pauli PhD; Ulf Dettmer PhD; Claudio O. Fernández PhD; Janin Lautenschläger PhD; Markus Zweckstetter PhD; Ruben Fernandez Busnadiego PhD; Brit Mollenhauer MD; Tiago Fleming Outeiro PhD

Current practices in the study of biomolecular condensates: a community comment 生物分子凝聚体研究中的当前实践：一篇社区评论

Nature Communications

IF15.7

2025-08-19

OAAI

Simon Alberti; Paolo Arosio; Robert B. Best; Steven Boeynaems; Danfeng Cai; Rosana Collepardo-Guevara; Gregory L. Dignon; Rumiana Dimova; Shana Elbaum-Garfinkle; Nicolas L. Fawzi; Monika Fuxreiter; Amy S. Gladfelter; Alf Honigmann; Ankur Jain; Jerelle A. Joseph; Tuomas P. J. Knowles; Keren Lasker; Edward A. Lemke; Kresten Lindorff-Larsen; Reinhard Lipowsky; Jeetain Mittal; Samrat Mukhopadhyay; Sua Myong; Rohit V. Pappu; Karsten Rippe; Tatyana A. Shelkovnikova; Anthony G. Vecchiarelli; Susanne Wegmann; Huaiying Zhang; Mingjie Zhang; Chloe Zubieta; Markus Zweckstetter; Dorothee Dormann; Tanja Mittag

Deep learning empowered sensor fusion boosts infant movement classification

COMMUNICATIONS MEDICINE

IF6.3

2025-01-14

OAAI

Kulvicius, Tomas; Zhang, Dajie; Poustka, Luise; Boelte, Sven; Jahn, Lennart; Fluegge, Sarah; Kraft, Marc; Zweckstetter, Markus; Nielsen-Saines, Karin; Woergoetter, Florentin; Marschik, Peter B.

Impact of distinct FG nucleoporin repeats on Nup98 self-association

NATURE COMMUNICATIONS

IF15.7

2024-05-07

OAAI

de Opakua, Alain Ibanez; Pantoja, Christian F.; Cima-Omori, Maria-Sol; Dienemann, Christian; Zweckstetter, Markus

Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions

NATURE COMMUNICATIONS

IF15.7

2024-03-02

OAAI

Anton, Rosa; Trevino, Miguel A.; Pantoja-Uceda, David; Felix, Sara; Babu, Maria; Cabrita, Eurico J.; Zweckstetter, Markus; Tinnefeld, Philip; Vera, Andres M.; Oroz, Javier

Regulation of tau by peptidyl-prolyl isomerases

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2024-02-01

OAAI

Zhuang, Shannon; Chakraborty, Pijush; Zweckstetter, Markus

Multimodal interactions drive chromatin phase separation and compaction 多模态相互作用驱动染色质相分离和压实

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-12-04

OAAI

Ukmar-Godec, Tina; Cima-Omori, Maria- Sol; Yerkesh, Zhadyra; Eswara, Karthik; Yu, Taekyung; Ramesh, Reshma; Riviere, Gwladys; de Opakua, Alain Ibanez; Fischle, Wolfgang; Zweckstetter, Markus

Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density

NATURE COMMUNICATIONS

IF15.7

2023-10-27

OAAI

Shen, Zheng; Sun, Daxiao; Savastano, Adriana; Varga, Sara Joana; Cima-Omori, Maria-Sol; Becker, Stefan; Honigmann, Alf; Zweckstetter, Markus

Role of aberrant phase separation in pathological protein aggregation

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-10-01

PREAI

Chakraborty, Pijush; Zweckstetter, Markus

Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II

NATURE COMMUNICATIONS

IF15.7

2023-09-25

OAAI

Flores-Solis, David; Lushpinskaia, Irina P.; Polyansky, Anton A.; Changiarath, Arya; Boehning, Marc; Mirkovic, Milana; Walshe, James; Pietrek, Lisa M.; Cramer, Patrick; Stelzl, Lukas S.; Zagrovic, Bojan; Zweckstetter, Markus

Acetylation discriminates disease-specific tau deposition

NATURE COMMUNICATIONS

IF15.7

2023-09-22

OAAI

Chakraborty, Pijush; Riviere, Gwladys; Hebestreit, Alina; de Opakua, Alain Ibanez; Vorberg, Ina M.; Andreas, Loren B.; Zweckstetter, Markus

Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology

NATURE COMMUNICATIONS

IF15.7

2023-09-06

OAAI

Huang, Yongqi; Wen, Jitao; Ramirez, Lisa-Marie; Guemuesdil, Eymen; Pokhrel, Pravin; Man, Viet H.; Ye, Haiqiong; Han, Yue; Liu, Yunfei; Li, Ping; Su, Zhengding; Wang, Junmei; Mao, Hanbin; Zweckstetter, Markus; Perrett, Sarah; Wu, Si; Gao, Meng

Alpha-synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain 多系统萎缩和帕金森氏病患者脑内注射后大脑扩散的 α-突触核蛋白原纤维

BRAIN PATHOLOGY

IF6.2

2023-07-24

OAAI

Zhang, Shuyu; Dauer, Karina; Strohaeker, Timo; Tatenhorst, Lars; Gomes, Lucas Caldi; Mayer, Simon; Jung, Byung Chul; Kim, Woojin S. S.; Lee, Seung-Jae; Becker, Stefan; Liesche-Starnecker, Friederike; Zweckstetter, Markus; Lingor, Paul

Molecular-level interplay between intrinsically disordered clients and Hsp90

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2023-06-01

PREAI

Ramirez, Lisa Marie; Zweckstetter, Markus

Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-05-22

OAAI

Yu, Taekyung; Flores-Solis, David; Eastep, Gunnar N.; Becker, Stefan; Zweckstetter, Markus

Tenth International Symposium on the Hsp90 chaperone machine Switzerland, October 19-23, 2022 第十届Hsp90伴侣机国际研讨会瑞士，2022年10月19至23日

CELL STRESS & CHAPERONES

IF3.2

2023-05-01

OAAI

Edkins, Adrienne L. L.; Zweckstetter, Markus; Sawarkar, Ritwick

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage

NATURE COMMUNICATIONS

IF15.7

2023-04-06

OAAI

Rosado-Ramos, Rita; Pocas, Goncalo M.; Marques, Daniela; Foito, Alexandre; Sevillano, David M.; Lopes-da-Silva, Mafalda; Goncalves, Luis G.; Menezes, Regina; Ottens, Marcel; Stewart, Derek; de Opakua, Alain Ibanez; Zweckstetter, Markus; Seabra, Miguel C.; Mendes, Cesar S.; Outeiro, Tiago Fleming; Domingos, Pedro M.; Santos, Claudia N.

研究方向