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Proteomic signatures of Alzheimer's disease and Lewy body dementias: A comparative analysis Canal-Garcia, Anna; Branca, Rui M.; Francis, Paul T.; Ballard, Clive; Winblad, Bengt; Lehtio, Janne; Nilsson, Per; Aarsland, Dag; Pereira, Joana B.; Bereczki, Erika 分享 收藏
A pragmatic, multicentre, double-blind, placebo-controlled randomised trial to assess the safety, clinical and cost-effectiveness of mirtazapine and carbamazepine in people with Alzheimer's disease and agitated behaviours: the HTA-SYMBAD trial Banerjee, Sube; Farina, Nicolas; Henderson, Catherine; High, Juliet; Stirling, Susan; Shepstone, Lee; Fountain, Julia; Ballard, Clive; Bentham, Peter; Burns, Alistair; Fox, Chris; Francis, Paul; Howard, Robert; Knapp, Martin; Leroi, Iracema; Livingston, Gill; Nilforooshan, Ramin; Nurock, Shirley; O'Brien, John; Price, Annabel; Thomas, Alan J.; Swart, Ann Marie; Telling, Tanya; Tabet, Naji 分享 收藏
Decreased DHA-containing phospholipids in the neocortex of dementia with Lewy bodies are associated with soluble Aβ42, phosphorylated α-synuclein, and synaptopathology Chong, Joyce R. R.; Chai, Yuek Ling; Xing, Huayang; Herr, Deron R.; Wenk, Markus R.; Francis, Paul T.; Ballard, Clive; Aarsland, Dag; Silver, David L.; Chen, Christopher P. P.; Cazenave-Gassiot, Amaury; Lai, Mitchell K. P. 分享 收藏
Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer's disease but not Lewy body dementias Chai, Yuek Ling; Lee, Jasinda H. H.; Chong, Joyce R. R.; Ballard, Clive; Francis, Paul T.; Kennedy, Brian K.; Arumugam, Thiruma V.; Chen, Christopher P. P.; Aarsland, Dag; Lai, Mitchell K. P. 分享 收藏
DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types 皮层中阿尔茨海默氏病神经病理学的DNA甲基化特征主要由非神经元细胞类型的变化驱动 Shireby, Gemma; Dempster, Emma L.; Policicchio, Stefania; Smith, Rebecca G.; Pishva, Ehsan; Chioza, Barry; Davies, Jonathan P.; Burrage, Joe; Lunnon, Katie; Vellame, Dorothea Seiler; Love, Seth; Thomas, Alan; Brookes, Keeley; Morgan, Kevin; Francis, Paul; Hannon, Eilis; Mill, Jonathan 分享 收藏
Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology 人类额叶皮层的表观基因组全关联研究确定了Lewy体病理学中的差异甲基化 Pihlstrom, Lasse; Shireby, Gemma; Geut, Hanneke; Henriksen, Sandra Pilar; Rozemuller, Annemieke J. M.; Tunold, Jon-Anders; Hannon, Eilis; Francis, Paul; Thomas, Alan J.; Love, Seth; Mill, Jonathan; van de Berg, Wilma D. J.; Toft, Mathias 分享 收藏
Relevance of sleep and associated structural changes in GBA1 mouse to human rapid eye movement behavior disorder Gelegen, Cigdem; Cash, Diana; Ilic, Katarina; Sander, Millie; Kim, Eugene; Simmons, Camilla; Bernanos, Michel; Lama, Joana; Randall, Karen; Brown, Jonathan T.; Kalanj-Bognar, Svjetlana; Cooke, Samuel; Chaudhuri, K. Ray; Ballard, Clive; Francis, Paul; Rosenzweig, Ivana 分享 收藏
A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex 阿尔茨海默氏病表观基因组全关联研究的荟萃分析突出了皮质中新的差异甲基化位点 Smith, Rebecca G.; Pishva, Ehsan; Shireby, Gemma; Smith, Adam R.; Roubroeks, Janou A. Y.; Hannon, Eilis; Wheildon, Gregory; Mastroeni, Diego; Gasparoni, Gilles; Riemenschneider, Matthias; Giese, Armin; Sharp, Andrew J.; Schalkwyk, Leonard; Haroutunian, Vahram; Viechtbauer, Wolfgang; van den Hove, Daniel L. A.; Weedon, Michael; Brokaw, Danielle; Francis, Paul T.; Thomas, Alan J.; Love, Seth; Morgan, Kevin; Walter, Joern; Coleman, Paul D.; Bennett, David A.; De Jager, Philip L.; Mill, Jonathan; Lunnon, Katie 分享 收藏
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Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease Lawingco, Ted; Chaudhury, Sultan; Brookes, Keeley J.; Guetta-Baranes, Tamar; Guerreiro, Rita; Bras, Jose; Hardy, John; Francis, Paul; Thomas, Alan; Belbin, Olivia; Morgan, Kevin 分享 收藏
Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementia 伴随的神经退行性疾病有助于从轻度认知障碍过渡到痴呆 McAleese, Kirsty E.; Colloby, Sean J.; Thomas, Alan J.; Al-Sarraj, Safa; Ansorge, Olaf; Neal, James; Roncaroli, Federico; Love, Seth; Francis, Paul T.; Attems, Johannes 分享 收藏
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Striatal Dopaminergic Deficit and Sleep in Idiopathic Rapid Eye Movement Behaviour Disorder: An Explorative Study 特发性快速眼动行为障碍的纹状体多巴胺能缺陷和睡眠: 一项探索性研究 Wasserman, Danielle; Bindman, Dorothea; Nesbitt, Alexander D.; Cash, Diana; Milosevic, Milan; Francis, Paul T.; Chaudhuri, K. Ray; Leschziner, Guy D.; Ferini-Strambi, Luigi; Ballard, Clive; Eccles, Amy; Rosenzweig, Ivana 分享 收藏
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Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex 重新校准表观遗传时钟: 评估人类大脑皮层生物年龄的意义 Shireby, Gemma L.; Davies, Jonathan P.; Francis, Paul T.; Burrage, Joe; Walker, Emma M.; Neilson, Grant W. A.; Dahir, Aisha; Thomas, Alan J.; Love, Seth; Smith, Rebecca G.; Lunnon, Katie; Kumari, Meena; Schalkwyk, Leonard C.; Morgan, Kevin; Brookes, Keeley; Hannon, Eilis; Mill, Jonathan 分享 收藏
Genetic risk for Alzheimer's disease influences neuropathology via multiple biological pathways Hannon, Eilis; Shireby, Gemma L.; Brookes, Keeley; Attems, Johannes; Sims, Rebecca; Cairns, Nigel J.; Love, Seth; Thomas, Alan J.; Morgan, Kevin; Francis, Paul T.; Mill, Jonathan 分享 收藏
Visual hallucinations in neurological and ophthalmological disease: pathophysiology and management O'Brien, John; Taylor, John Paul; Ballard, Clive; Barker, Roger A.; Bradley, Clare; Burns, Alistair; Collerton, Daniel; Dave, Sonali; Dudley, Rob; Francis, Paul; Gibbons, Andrea; Harris, Kate; Lawrence, Vanessa; Leroi, Iracema; McKeith, Ian; Michaelides, Michel; Naik, Chaitali; O'Callaghan, Claire; Olsen, Kirsty; Onofrj, Marco; Pinto, Rebecca; Russell, Gregor; Swann, Peter; Thomas, Alan; Urwyler, Prabitha; Weil, Rimona Sharon; Ffytche, Dominic 分享 收藏
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