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Thomas D. Hurley

indiana university system

55H指数
226论文数
9.6K被引数
收录论文 50
发表时间
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Impaired malin expression and interaction with partner proteins in Lafora diseaseLafora病中malin表达受损及其与伴侣蛋白的相互作用
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-05-01
err1
errOAAI
errSkurat, Alexander, V; Segvich, Dyann M.; Contreras, Christopher J.; Hu, Yueh-Chiang; Hurley, Thomas D.; DePaoli-Roach, Anna A.; Roach, Peter J.
err分享
err收藏
Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-01-17
err9
PREAI
errUllman, Julie C.; Mellem, Kevin T.; Xi, Yannan; Ramanan, Vyas; Merritt, Hanne; Choy, Rebeca; Gujral, Tarunmeet; Young, Lyndsay E. A.; Blake, Kerrigan; Tep, Samnang; Homburger, Julian R.; O'Regan, Adam; Ganesh, Sandya; Wong, Perryn; Satterfield, Terrence F.; Lin, Baiwei; Situ, Eva; Yu, Cecile; Espanol, Bryan; Sarwaikar, Richa; Fastman, Nathan; Tzitzilonis, Christos; Lee, Patrick; Reiton, Daniel; Morton, Vivian; Santiago, Pam; Won, Walter; Powers, Hannah; Cummings, Beryl B.; Hoek, Maarten; Graham, Robert R.; Chandriani, Sanjay J.; Bainer, Russell; DePaoli-Roach, Anna A.; Roach, Peter J.; Hurley, Thomas D.; Sun, Ramon C.; Gentry, Matthew S.; Sinz, Christopher; Dick, Ryan A.; Noonberg, Sarah B.; Beattie, David T.; Morgans Jr, David J.; Green, Eric M.
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The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex
errCELL REPORTS
IF6.9
err2022-07-01
err13
errOAAI
errFastman, Nathan M.; Liu, Yuxi; Ramanan, Vyas; Merritt, Hanne; Ambing, Eileen; DePaoli-Roach, Anna A.; Roach, Peter J.; Hurley, Thomas D.; Mellem, Kevin T.; Ullman, Julie C.; Green, Eric; Morgans, Jr. David; Tzitzilonis, Christos
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err收藏
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation
errCELL METABOLISM
IF30.9
err2021-07-01
err49
errOAAI
errSun, Ramon C.; Young, Lyndsay E. A.; Bruntz, Ronald C.; Markussen, Kia H.; Zhou, Zhengqiu; Conroy, Lindsey R.; Hawkinson, Tara R.; Clarke, Harrison A.; Stanback, Alexandra E.; Macedo, Jessica K. A.; Emanuelle, Shane; Brewer, M. Kathryn; Rondon, Alberto L.; Mestas, Annette; Sanders, William C.; Mahalingan, Krishna K.; Tang, Buyun; Chikwana, Vimbai M.; Segvich, Dyann M.; Contreras, Christopher J.; Allenger, Elizabeth J.; Brainson, Christine F.; Johnson, Lance A.; Taylor, Richard E.; Armstrong, Dustin D.; Shaffer, Robert; Waechter, Charles J.; Vander Kooi, Craig W.; DePaoli-Roach, Anna A.; Roach, Peter J.; Hurley, Thomas D.; Drake, Richard R.; Gentry, Matthew S.
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Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2021-02-01
err13
errOAAI
errHuddle, Brandt C.; Grimley, Edward; Chtcherbinine, Mikhail; Buchman, Cameron D.; Takahashi, Cyrus; Debnath, Bikash; McGonigal, Stacy C.; Mao, Shuai; Li, Siwei; Felton, Jeremy; Pan, Shu; Wen, Bo; Sun, Duxin; Neamati, Nouri; Buckanovich, Ronald J.; Hurley, Thomas D.; Larsen, Scott D.
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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-03-05
err46
errOAAI
errTang, Buyun; Frasinyuk, Mykhaylo S.; Chikwana, Vimbai M.; Mahalingan, Krishna K.; Morgan, Cynthia A.; Segvich, Dyann M.; Bondarenko, Svitlana P.; Mrug, Galyna P.; Wyrebek, Przemyslaw; Watt, David S.; DePaoli-Roach, Anna A.; Roach, Peter J.; Hurley, Thomas D.
err分享
err收藏
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells
errCELL REPORTS
IF6.9
err2019-03-01
err124
errOAAI
errChefetz, Ilana; Grimley, Edward; Yang, Kun; Hong, Linda; Vinogradova, Ekaterina V.; Suciu, Radu; Kovalenko, Ilya; Karnak, David; Morgan, Cynthia A.; Chtcherbinine, Mikhail; Buchman, Cameron; Huddle, Brandt; Barraza, Scott; Morgan, Meredith; Bernstein, Kara A.; Yoon, Euisik; Lombard, David B.; Bild, Andrea; Mehta, Geeta; Romero, Iris; Chiang, Chun-Yi; Landen, Charles; Cravatt, Benjamin; Hurley, Thomas D.; Larsen, Scott D.; Buckanovich, Ronald J.
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ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells
errCELL CHEMICAL BIOLOGY
IF7.2
err2018-12-01
err47
errOAAI
errSarvi, Sana; Crispin, Richard; Lu, Yuting; Zeng, Lifan; Hurley, Thomas D.; Houston, Douglas R.; von Kriegsheim, Alex; Chen, Che-Hong; Mochly-Rosen, Daria; Ranzani, Marco; Mathers, Marie E.; Xu, Xiaowei; Xu, Wei; Adams, David J.; Carragher, Neil O.; Fujita, Mayumi; Schuchter, Lynn; Unciti-Broceta, Asier; Brunton, Valerie G.; Patton, E. Elizabeth
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Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2018-09-17
err60
errOAAI
errHuddle, Brandt C.; Grimley, Edward; Buchman, Cameron D.; Chtcherbinine, Mikhail; Debnath, Bikash; Mehta, Pooja; Yang, Kun; Morgan, Cynthia A.; Li, Siwei; Felton, Jeremy; Sun, Duxin; Mehta, Geeta; Neamati, Nouri; Buckanovich, Ronald J.; Hurley, Thomas D.; Larsen, Scott D.
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Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2017-03-06
err42
errOAAI
errBuchman, Cameron D.; Hurley, Thomas D.
err分享
err收藏
Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells脂质去饱和是卵巢癌干细胞的代谢标志物和治疗靶点
errCELL STEM CELL
IF20.4
err2017-03-01
err462
errOAAI
errLi, Junjie; Condello, Salvatore; Thomes-Pepin, Jessica; Ma, Xiaoxiao; Xia, Yu; Hurley, Thomas D.; Matei, Daniela; Cheng, Ji-Xin
err分享
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Incorporation of phosphate into glycogen by glycogen synthase
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2016-05-01
err18
errOAAI
errContreras, Christopher J.; Segvich, Dyann M.; Mahalingan, Krishna; Chikwana, Vimbai M.; Kirley, Terence L.; Hurley, Thomas D.; DePaoli-Roach, Anna A.; Roach, Peter J.
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err收藏
Characterization of Two Distinct Structural Classes of Selective Aldehyde Dehydrogenase 1A1 Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2015-02-10
err83
errOAAI
errMorgan, Cynthia A.; Hurley, Thomas D.
err分享
err收藏
Hominids adapted to metabolize ethanol long before human-directed fermentation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2014-12-01
err93
errOAAI
errCarrigan, Matthew A.; Uryasev, Oleg; Frye, Carole B.; Eckman, Blair L.; Myers, Candace R.; Hurley, Thomas D.; Benner, Steven A.
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err收藏
Enrichment of Chemical Libraries Docked to Protein Conformational Ensembles and Application to Aldehyde Dehydrogenase 2
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2014-06-30
err16
errOAAI
errWang, Bo; Buchman, Cameron D.; Li, Liwei; Hurley, Thomas D.; Meroueh, Samy O.
err分享
err收藏
β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroids
errONCOGENE
IF7.3
err2014-06-23
err156
errOAAI
errCondello, S.; Morgan, C. A.; Nagdas, S.; Cao, L.; Turek, J.; Hurley, T. D.; Matei, D.
err分享
err收藏
Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2014-01-31
err47
errOAAI
errKimble-Hill, Ann C.; Parajuli, Bibek; Chen, Che-Hong; Mochly-Rosen, Daria; Hurley, Thomas D.
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Selective ALDH3A1 Inhibition by Benzimidazole Analogues Increase Mafosfamide Sensitivity in Cancer Cells
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2014-01-10
err69
errOAAI
errParajuli, Bibek; Fishel, Melissa L.; Hurley, Thomas D.
err分享
err收藏
The Role of Phosphoinositol Lipids in Amot Membrane Association
errBIOPHYSICAL JOURNAL
IF3.1
err2014-01-01
err0
errOAAI
errKimble-Hill, Ann C.; Johnson, Merrell; Firestone, Millicent A.; Petrache, Horia; Hurley, Thomas D.; Wells, Clark D.; Seifert, Soenke
err分享
err收藏
Toward Understanding the Role of Amot80 Lipid Binding in Cellular Proliferation and Migration
errBIOPHYSICAL JOURNAL
IF3.1
err2014-01-01
err0
errOAAI
errDonovan, Emily L.; Kimble-Hill, Ann C.; Hurley, Thomas D.; Wells, Clark D.
err分享
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研究方向

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合作学者
合作期刊
B
Benjamin F. Cravatt
H 指数: 148 · 论文数: 867
J
Jonathan S. Stamler
H 指数: 131 · 论文数: 421
D
David J. Adams
H 指数: 113 · 论文数: 968
D
Daria Mochly‐Rosen
H 指数: 99 · 论文数: 474
M
Markus Grompe
H 指数: 96 · 论文数: 404
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