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Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants Hincelin-Mery, Agnes; Nicolas, Xavier; Cantalloube, Cathy; Pomponio, Robert; Lewanczyk, Pascale; Benamor, Myriam; Ofengeim, Dimitry; Krupka, Emmanuel; Hsiao-Nakamoto, Jennifer; Eastenson, Amy; Atassi, Nazem 分享 收藏
An innovative phase 2 proof-of-concept trial design to evaluate SAR445088, a monoclonal antibody targeting complement C1s in chronic inflammatory demyelinating polyneuropathy Querol, Luis; Lewis, Richard A.; Hartung, Hans-Peter; Van Doorn, Pieter A.; Wallstroem, Erik; Luo, Xiaodong; Alonso-Alonso, Miguel; Atassi, Nazem; Hughes, Richard A. C. 分享 收藏
Classical Complement Pathway Inhibition in a Human-On-A-Chip Model of Autoimmune Demyelinating Neuropathies Rumsey, John W.; Lorance, Case; Jackson, Max; Sasserath, Trevor; McAleer, Christopher W.; Long, Christopher J.; Goswami, Arindom; Russo, Melissa A.; Raja, Shruti M.; Gable, Karissa L.; Emmett, Doug; Hobson-Webb, Lisa D.; Chopra, Manisha; Howard, James F., Jr.; Guptill, Jeffrey T.; Storek, Michael J.; Alonso-Alonso, Miguel; Atassi, Nazem; Panicker, Sandip; Parry, Graham; Hammond, Timothy; Hickman, James J. 分享 收藏
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Selective atrophy of the cervical enlargement in whole spinal cord MRI of amyotrophic lateral sclerosis Barry, Robert L.; Torrado-Carvajal, Angel; Kirsch, John E.; Arabasz, Grae E.; Albrecht, Daniel S.; Alshelh, Zeynab; Pijanowski, Olivia; Lewis, Austin J.; Keegan, Mackenzie; Reynolds, Beverly; Knight, Paulina C.; Morrissey, Erin J.; Loggia, Marco L.; Atassi, Nazem; Hooker, Jacob M.; Babu, Suma 分享 收藏
Comparison of Two Clinical Upper Motor Neuron Burden Rating Scales in ALS Using Quantitative Brain Imaging Makary, Meena M.; Weerasekara, Akila; Rodham, Haley; Hightower, Baileigh G.; Tseng, Chieh-En J.; Chan, James; Chew, Sheena; Paganoni, Sabrina; Ratai, Eva-Maria; Zurcher, Nicole R.; Hooker, Jacob M.; Atassi, Nazem; Babu, Suma 分享 收藏
Ultra-high field (7T) functional magnetic resonance imaging in amyotrophic lateral sclerosis: a pilot study Barry, Robert L.; Babu, Suma; Anteraper, Sheeba Arnold; Triantafyllou, Christina; Keil, Boris; Rowe, Olivia E.; Rangaprakash, D.; Paganoni, Sabrina; Lawson, Robert; Dheel, Christina; Cernasov, Paul M.; Rosen, Bruce R.; Ratai, Eva-Maria; Atassi, Nazem 分享 收藏
Ibudilast (MN-166) in amyotrophic lateral sclerosis- an open label, safety and pharmacodynamic trial Babu, Suma; Hightower, Baileigh G.; Chan, James; Zurcher, Nicole R.; Kivisakk, Pia; Tseng, Chieh-En J.; Sanders, Danica L.; Robichaud, Ashley; Banno, Haruhiko; Evora, Armineuza; Ashokkumar, Akshata; Pothier, Lindsay; Paganoni, Sabrina; Chew, Sheena; Dojillo, Joanna; Matsuda, Kazuko; Gudesblatt, Mark; Berry, James D.; Cudkowicz, Merit E.; Hooker, Jacob M.; Atassi, Nazem 分享 收藏
Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS Miller, Timothy; Cudkowicz, Merit; Shaw, Pamela J.; Andersen, Peter M.; Atassi, Nazem; Bucelli, Robert C.; Genge, Angela; Glass, Jonathan; Ladha, Shafeeq; Ludolph, Albert L.; Maragakis, Nicholas J.; McDermott, Christopher J.; Pestronk, Alan; Ravits, John; Salachas, Francois; Trudell, Randall; Van Damme, Philip; Zinman, Lorne; Bennett, C. Frank; Lane, Roger; Sandrock, Alfred; Runz, Heiko; Graham, Danielle; Houshyar, Hani; McCampbell, Alexander; Nestorov, Ivan; Chang, Ih; McNeill, Manjit; Fanning, Laura; Fradette, Stephanie; Ferguson, Toby A. 分享 收藏
Moving Toward Multicenter Therapeutic Trials in Amyotrophic Lateral Sclerosis: Feasibility of Data Pooling Using Different Translocator Protein PET Radioligands Van Weehaeghe, Donatienne; Babu, Suma; De Vocht, Joke; Zurcher, Nicole R.; Chew, Sheena; Tseng, Chieh-En J.; Loggia, Marco L.; Koole, Michel; Rezaei, Ahmadreza; Schramm, Georg; Van Damme, Philip; Hooker, Jacob M.; Van Laere, Koen; Atassi, Nazem 分享 收藏
Multi-Modal Signatures of Tau Pathology, Neuronal Fiber Integrity, and Functional Connectivity in Traumatic Brain Injury Wooten, Dustin W.; Ortiz-Teran, Laura; Zubcevik, Nevena; Zhang, Xiaomeng; Huang, Chuan; Sepulcre, Jorge; Atassi, Nazem; Johnson, Keith A.; Zafonte, Ross D.; El Fakhri, Georges 分享 收藏
Prospective natural history study of C9orf72 ALS clinical characteristics and biomarkers Cammack, Alexander J.; Atassi, Nazem; Hyman, Theodore; van den Berg, Leonard H.; Harms, Matthew; Baloh, Robert H.; Brown, Robert H.; van Es, Michael A.; Veldink, Jan H.; de Vries, Balint S.; Rothstein, Jeffrey D.; Drain, Caroline; Jockel-Balsarotti, Jennifer; Malcolm, Amber; Boodram, Sonia; Salter, Amber; Wightman, Nicholas; Yu, Hong; Sherman, Alexander, V; Esparza, Thomas J.; McKenna-Yasek, Diane; Owegi, Margaret A.; Douthwright, Catherine; McCampbell, Alexander; Ferguson, Toby; Cruchaga, Carlos; Cudkowicz, Merit; Miller, Timothy M. 分享 收藏
Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach 肌萎缩侧索硬化症患者的分层: 众包方法 Kueffner, Robert; Zach, Neta; Bronfeld, Maya; Norel, Raquel; Atassi, Nazem; Balagurusamy, Venkat; Di Camillo, Barbara; Chio, Adriano; Cudkowicz, Merit; Dillenberger, Donna; Garcia-Garcia, Javier; Hardiman, Orla; Hoff, Bruce; Knight, Joshua; Leitner, Melanie L.; Li, Guang; Mangravite, Lara; Norman, Thea; Wang, Liuxia; Alkallas, Rached; Anghel, Catalina; Avril, Jeanne; Bacardit, Jaume; Balser, Barbara; Balser, John; Bar-Sinai, Yoav; Ben-David, Noa; Ben-Zion, Eyal; Bliss, Robin; Cai, Jialu; Chernyshev, Anatoly; Chiang, Jung-Hsien; Chicco, Davide; Corriveau, Bhavna Ahuja Nicole; Dai, Junqiang; Deshpande, Yash; Desplats, Eve; Durgin, Joseph S.; Espiritu, Shadrielle Melijah G.; Fan, Fan; Fevrier, Philippe; Fridley, Brooke L.; Godzik, Adam; Golinska, Agnieszka; Gordon, Jonathan; Graw, Stefan; Guo, Yuelong; Herpelinck, Tim; Hopkins, Julia; Huang, Barbara; Jacobsen, Jeremy; Jahandideh, Samad; Jeon, Jouhyun; Ji, Wenkai; Jung, Kenneth; Karanevich, Alex; Koestler, Devin C.; Kozak, Michael; Kurz, Christoph; Lalansingh, Christopher; Larrieu, Thomas; Lazzarini, Nicola; Lerner, Boaz; Lesinski, Wojciech; Liang, Xiaotao; Lin, Xihui; Lowe, Jarrett; Mackey, Lester; Meier, Richard; Min, Wenwen; Mnich, Krzysztof; Nahmias, Violette; Noel-MacDonnell, Janelle; O'Donnell, Adrienne; Paadre, Susan; Park, Ji; Polewko-Klim, Aneta; Raghavan, Rama; Rudnicki, Witold; Saghapour, Ehsan; Salomond, Jean-Bernard; Sankaran, Kris; Sendorek, Dorota; Sharan, Vatsal; Shiah, Yu-Jia; Sirois, Jean-Karl; Sumanaweera, Dinithi N.; Usset, Joseph; Vang, Yeeleng S.; Vens, Celine; Wadden, Dave; Wang, David; Wong, Wing Chung; Xie, Xiaohui; Xu, Zhiqing; Yang, Hsih-Te; Yu, Xiang; Zhang, Haichen; Zhang, Li; Zhang, Shihua; Zhu, Shanfeng; Xiao, Jinfeng; Fang, Wen-Chieh; Peng, Jian; Yang, Chen; Chang, Huan-Jui; Stolovitzky, Gustavo 分享 收藏
Implementing Motor Unit Number Index (MUNIX) in a large clinical trial: Real world experience from 27 centres Neuwirth, Christoph; Braun, Nathalie; Claeys, Kristl G.; Bucelli, Robert; Fournier, Christina; Bromberg, Mark; Petri, Susanne; Goedee, Stephan; Lenglet, Timothee; Leppanen, Ron; Canosa, Antonio; Goodman, Ira; Al-Lozi, Muhammad; Ohkubo, Takuya; Huebers, Annemarie; Atassi, Nazem; Abrahao, Agessandro; Funke, Andreas; Appelfeller, Martin; Tuemmler, Anke; Finegan, Eoin; Glass, Jonathan D.; Babu, Suma; Ladha, Shafeeq S.; Kwast-Rabben, Olga; Juntas-Morales, Raul; Coffey, Amina; Chaudhry, Vinay; Vu, Tuan; Saephanh, Chow; Newhard, Colleen; Zakrzewski, Marion; Rosier, Esther; Hamel, Nancy; Raheja, Divisha; Raaijman, Jesper; Ferguson, Toby; Weber, Markus 分享 收藏
Integrated magnetic resonance imaging and [11C]-PBR28 positron emission tomographic imaging in amyotrophic lateral sclerosis Alshikho, Mohamad J.; Zuercher, Nicole R.; Loggia, Marco L.; Cernasov, Paul; Reynolds, Beverly; Pijanowski, Olivia; Chonde, Daniel B.; Izquierdo Garcia, David; Mainero, Caterina; Catana, Ciprian; Chan, James; Babu, Suma; Paganoni, Sabrina; Hooker, Jacob M.; Atassi, Nazem 分享 收藏
Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS Goutman, Stephen A.; Brown, Morton B.; Glass, Jonathan D.; Boulis, Nicholas M.; Johe, Karl; Hazel, Tom; Cudkowicz, Merit; Atassi, Nazem; Borges, Lawrence; Patil, Parag G.; Sakowski, Stacey A.; Feldman, Eva L. 分享 收藏
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Head-to-Head Comparison of 11C-PBR28 and 18F-GE180 for Quantification of the Translocator Protein in the Human Brain Zanotti-Fregonara, Paolo; Pascual, Belen; Rizzo, Gaia; Yu, Meixiang; Pal, Neha; Beers, David; Carter, Randall; Appel, Stanley H.; Atassi, Nazem; Masdeu, Joseph C. 分享 收藏
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