Mario Zoratti

University of Padua

61H指数

190论文数

1.4W被引数

收录论文 75

发表时间

Tumor-specific targeting of a mitochondrial Kv1.3 channel inhibitor through conjugation to gastrin/cholecystokinin B receptor ligand strongly reduces pancreatic ductal adenocarcinoma in orthotopic models 通过将线粒体Kv1.3通道抑制剂与胃泌素/胆囊收缩素B受体配体缀合进行肿瘤特异性靶向，可显著降低正位胰腺导管腺癌模型中的肿瘤负荷。

Pharmacological Research

IF10.5

2026-02-20

OAAI

Sofia Parrasia; Carlotta Paoli; Tatiana Varanita; Valentina Brillo; Mostafa A.L Abdel-Salam; Alberto Ongaro; Claudia Hornisch; Beatrice Angi; Magdalena Bachmann; Filippo Bergamin; Vincenzo Corbo; Elena Fiorini; Andrea Rossa; Giovanna Bossio; Erich Gulbins; Alessandro Carrer; Mario Zoratti; Andrea Mattarei; Paolo Ruzza; Lucia Biasutto

Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo 线粒体钙依赖性钾通道KCa3.1的药理学靶向触发细胞死亡并减少体内肿瘤生长和转移

CELL DEATH & DISEASE

IF9.6

2022-12-20

OAAI

Bachmann, Magdalena; Rossa, Andrea; Varanita, Tatiana; Fioretti, Bernard; Biasutto, Lucia; Milenkovic, Stefan; Checchetto, Vanessa; Peruzzo, Roberta; Ahmad, Syed A.; Patel, Sameer H.; Lukowski, Robert; Edwards, Michael J.; Ceccarelli, Matteo; Gulbins, Erich; Zoratti, Mario; Mattarei, Andrea; Szabo, Ildiko

Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IF12.8

2022-02-16

OAAI

Severin, Filippo; Urbani, Andrea; Varanita, Tatiana; Bachmann, Magdalena; Azzolini, Michele; Martini, Veronica; Pizzi, Marco; Dei Tos, Angelo Paolo; Frezzato, Federica; Mattarei, Andrea; Ghia, Paolo; Bertilaccio, Maria Teresa Sabrina; Gulbins, Erich; Paradisi, Cristina; Zoratti, Mario; Semenzato, Gianpietro Carlo; Leanza, Luigi; Trentin, Livio; Szabo, Ildiko

Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction 利用pycyanin治疗由于呼吸复合物III功能障碍引起的线粒体疾病

NATURE COMMUNICATIONS

IF15.7

2021-04-08

OAAI

Peruzzo, Roberta; Corra, Samantha; Costa, Roberto; Brischigliaro, Michele; Varanita, Tatiana; Biasutto, Lucia; Rampazzo, Chiara; Ghezzi, Daniele; Leanza, Luigi; Zoratti, Mario; Zeviani, Massimo; De Pitta, Cristiano; Viscomi, Carlo; Costa, Rodolfo; Szabo, Ildiko

An Angiopep2-PAPTP Construct Overcomes the Blood-Brain Barrier. New Perspectives against Brain Tumors

PHARMACEUTICALS

IF4.8

2021-02-06

OAAI

Parrasia, Sofia; Rossa, Andrea; Varanita, Tatiana; Checchetto, Vanessa; De Lorenzi, Riccardo; Zoratti, Mario; Paradisi, Cristina; Ruzza, Paolo; Mattarei, Andrea; Szabo, IldikO; Biasutto, Lucia

Synthesis and cellular effects of a mitochondria-targeted inhibitor of the two-pore potassium channel TASK-3 两孔钾通道TASK-3的线粒体靶向抑制剂的合成和细胞作用

PHARMACOLOGICAL RESEARCH

IF10.5

2021-02-01

OAAI

Bachmann, Magdalena; Rossa, Andrea; Antoniazzi, Giuseppe; Biasutto, Lucia; Carrer, Andrea; Campagnaro, Monica; Leanza, Luigi; Gonczi, Monika; Csernoch, Laszlo; Paradisi, Cristina; Mattarei, Andrea; Zoratti, Mario; Szabo, Ildiko

Strategies to target bioactive molecules to subcellular compartments. Focus on natural compounds 将生物活性分子靶向亚细胞区室的策略。专注于天然化合物

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-11-01

PREAI

Biasutto, Lucia; Mattarei, Andrea; La Spina, Martina; Azzolini, Michele; Parrasia, Sofia; Szabo, Ildiko; Zoratti, Mario

Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction 受损的线粒体ATP产生通过ER应激诱导下调Wnt信号传导

CELL REPORTS

IF6.9

2019-08-01

OAAI

Costa, Roberto; Peruzzo, Roberta; Bachmann, Magdalena; Dalla Monta, Giulia; Vicario, Mattia; Santinon, Giulia; Mattarei, Andrea; Moro, Enrico; Quintana-Cabrera, Ruben; Scorranot, Luca; Zeviani, Massimo; Vallese, Francesca; Zoratti, Mario; Paradisi, Cristina; Argenton, Francesco; Brini, Marisa; Cali, Tito; Dupont, Sirio; Szabo, Ildiko; Leanza, Luigi

Pharmacological modulation of mitochondrial ion channels

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2019-01-02

OAAI

Leanza, Luigi; Checchetto, Vanessa; Biasutto, Lucia; Rossa, Andrea; Costa, Roberto; Bachmann, Magdalena; Zoratti, Mario; Szabo, Ildiko

Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents

FRONTIERS IN ONCOLOGY

IF3.3

2018-04-23

OAAI

Mattarei, Andrea; Romio, Matteo; Manago, Antonella; Zoratti, Mario; Paradisi, Cristina; Szabo, Ildiko; Leanza, Luigi; Biasutto, Lucia

LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux

FRONTIERS IN PHYSIOLOGY

IF3.4

2017-11-17

OAAI

Austin, Shane; Tavakoli, Mojtaba; Pfeiffer, Christina; Seifert, Julia; Mattarei, Andrea; De Stefani, Diego; Zoratti, Mario; Nowikovsky, Karin

Potential anti-cancer activity of 7-O-pentyl quercetin: Efficient, membrane-targeted kinase inhibition and pro-oxidant effect

PHARMACOLOGICAL RESEARCH

IF10.5

2017-10-01

PREAI

Sassi, Nicola; Mattarei, Andrea; Espina, Virginia; Liotta, Lance; Zoratti, Mario; Paradisi, Cristina; Biasutto, Lucia

Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells

FRONTIERS IN ONCOLOGY

IF3.3

2017-09-29

OAAI

Peruzzo, Roberta; Mattarei, Andrea; Romio, Matteo; Paradisi, Cristina; Zoratti, Mario; Szabo, Ildik; Leanza, Luigi

Mitochondrial genetic haplogroups and depressive symptoms: A large study among people in North America

JOURNAL OF AFFECTIVE DISORDERS

IF4.9

2017-08-01

OAAI

Veronese, Nicola; Stubbs, Brendon; Solmi, Marco; Vaona, Alberto; Demurtas, Jacopo; Carvalho, Andre F.; Koyanagi, Ai; Thompson, Trevor; Zoratti, Mario; Maggi, Stefania

Resveratrol derivatives as a pharmacological tool

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

IF4.8

2017-07-04

PREAI

Biasutto, Lucia; Mattarei, Andrea; Azzolini, Michele; La Spina, Martina; Sassi, Nicola; Romio, Matteo; Paradisi, Cristina; Zoratti, Mario

Novel lipid-mimetic prodrugs delivering active compounds to adipose tissue 新型脂质模拟前药将活性化合物递送至脂肪组织

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-07-01

PREAI

Mattarei, Andrea; Rossa, Andrea; Bombardelli, Veronica; Azzolini, Michele; La Spina, Martina; Paradisi, Cristina; Zoratti, Mario; Biasutto, Lucia

Now UCP(rotein), Now You Don't: UCP1 Is Not Mandatory for Thermogenesis

CELL METABOLISM

IF30.9

2017-04-01

OAAI

Szabo, Ildiko; Zoratti, Mario

Early effects of the antineoplastic agent salinomycin on mitochondrial function

CELL DEATH & DISEASE

IF9.6

2015-10-22

OAAI

Manago, A.; Leanza, L.; Carraretto, L.; Sassi, N.; Grancara, S.; Quintana-Cabrera, R.; Trimarco, V.; Toninello, A.; Scorrano, L.; Trentin, L.; Semenzato, G.; Gulbins, E.; Zoratti, M.; Szabo, I.

Amino Acid Carbamates As Prodrugs Of Resveratrol

SCIENTIFIC REPORTS

IF3.9

2015-10-14

OAAI

Mattarei, Andrea; Azzolini, Michele; La Spina, Martina; Zoratti, Mario; Paradisi, Cristina; Biasutto, Lucia

N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol

MOLECULES

IF4.6

2015-09-03

OAAI

Mattarei, Andrea; Azzolini, Michele; Zoratti, Mario; Biasutto, Lucia; Paradisi, Cristina

研究方向