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L

Leonard Post

University of Colorado System

41H指数
185论文数
10.0K被引数
收录论文 23
发表时间
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Evaluating the Use of Merlin-YAP Dual-label Immunohistochemistry for Predicting Response to TEAD Inhibitor VT3989
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errTang, T.; Gordon, K.; Li, Y.; Lewis, J.; McBrearty, N.; Sharma, N.; Post, L.
err分享
err收藏
Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription识别小分子抑制TEAD调节的转录的抗性机制
errEMBO REPORTS
IF6.2
err2024-08-05
err0
PREAI
errKulkarni, Aishwarya; Mohan, Varshini; Tang, Tracy T.; Post, Leonard; Chan, Yih-Chih; Manning, Murray; Thio, Niko; Parker, Benjamin L.; Dawson, Mark A.; Rosenbluh, Joseph; Vissers, Joseph H. A.; Harvey, Kieran F.
err分享
err收藏
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer
errNATURE COMMUNICATIONS
IF15.7
err2024-05-03
err10
errOAAI
errHaderk, Franziska; Chou, Yu-Ting; Cech, Lauren; Fernandez-Mendez, Celia; Yu, Johnny; Olivas, Victor; Meraz, Ismail M.; Rabago, Dora Barbosa; Kerr, D. Lucas; Gomez, Carlos; Allegakoen, David V.; Guan, Juan; Shah, Khyati N.; Herrington, Kari A.; Gbenedio, Oghenekevwe M.; Nanjo, Shigeki; Majidi, Mourad; Tamaki, Whitney; Pourmoghadam, Yashar K.; Rotow, Julia K.; McCoach, Caroline E.; Riess, Jonathan W.; Gutkind, J. Silvio; Tang, Tracy T.; Post, Leonard; Huang, Bo; Santisteban, Pilar; Goodarzi, Hani; Bandyopadhyay, Sourav; Kuo, Calvin J.; Roose, Jeroen P.; Wu, Wei; Blakely, Collin M.; Roth, Jack A.; Bivona, Trever G.
err分享
err收藏
Comparing TEAD palmitoylation inhibitors with differential TEAD selectivity in combination efficacy with targeted therapies and in renal safety
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errTang, Tracy T.; Post, Leonard
err分享
err收藏
VT3989, the first-in-class and first-in-human TEAD auto-palmitoylation inhibitor, enhances the efficacy and durability of multiple targeted therapies of the MAPK and P13K/AKT/mTOR pathways
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-12-01
err0
PREAI
errTang, Tracy T.; Post, Leonard
err分享
err收藏
TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C InhibitorsTEAD抑制克服了YAP1/TAZ驱动的对KRASG12C抑制剂的原发性和获得性抗性
errCANCER RESEARCH
IF16.6
err2023-11-07
err18
errOAAI
errEdwards, A. Cole; Stalnecker, Clint A.; Morales, Alexis Jean; Taylor, Khalilah E.; Klomp, Jennifer E.; Klomp, Jeffrey A.; Waters, Andrew M.; Sudhakar, Niranjan; Hallin, Jill; Tang, Tracy T.; Olson, Peter; Post, Leonard; Christensen, James G.; Cox, Adrienne D.; Der, Channing J.
err分享
err收藏
CD38 x ICAM-1 Bispecific Antibody Is a Novel Approach for Treating Multiple Myeloma and Lymphoma
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-10-10
err3
PREAI
errChen, Xiaocheng; Wong, Oi Kwan; Reiman, Lauren; Sherbenou, Daniel W.; Post, Leonard
err分享
err收藏
A novel topoisomerase I inhibitor based anti-ICAM-1 antibody drug conjugate for the treatment of hematologic malignancies and solid tumors
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errWong, Oi Kwan; Jackson, David; Shi, Lei; Fei, Qi; Chen, Xiaocheng; Post, Leonard
err分享
err收藏
VBI-002, a CD47xICAM-1 bispecific antibody for the treatment of hepatocellular carcinoma, melanoma and non-small cell lung cancers
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errWong, Oi Kwan; Wang, Xinhua; Post, Leonard; Chen, Xiaocheng
err分享
err收藏
VBI-003, a CD47xEpCAM bispecific antibody as a potential treatment for colorectal and small cell lung cancers
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errWong, Oi Kwan; Wang, Xinhua; Chen, Xiaocheng; Post, Leonard
err分享
err收藏
Inhibition of YAP/TAZ-driven TEAD activity prevents growth of NF2-null schwannoma and meningioma
errBRAIN
IF11.7
err2022-09-23
err24
errOAAI
errLaraba, Liyam; Hillson, Lily; de Guibert, Julio Grimm; Hewitt, Amy; Jaques, Maisie R.; Tang, Tracy T.; Post, Leonard; Ercolano, Emanuela; Rai, Ganesha; Yang, Shyh-Ming; Jagger, Daniel J.; Woznica, Waldemar; Edwards, Philip; Shivane, Aditya G.; Hanemann, C. Oliver; Parkinson, David B.
err分享
err收藏
Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2021-04-13
err145
errOAAI
errTang, Tracy T.; Konradi, Andrei W.; Feng, Ying; Peng, Xiao; Mae, Mingyue; Lie, Jian; Yu, Fa-Xing; Guan, Kun-Liang; Post, Leonard
err分享
err收藏
TEAD inhibition reduces tumor proliferation in Merlin null meningioma and schwannoma
errCANCER RESEARCH
IF16.6
err2020-08-15
err1
PREAI
errLaraba, Liyam; de Guibert, Julio Grimm; Tang, Tracy T.; Post, Leonard; Parkinson, David B.
err分享
err收藏
Targeting the Hippo-YAP pathway with novel small-molecule inhibitors of the YAP-TEAD transcription activity
errCANCER RESEARCH
IF16.6
err2019-07-01
err3
PREAI
errTang, Tracy T.; Konradi, Andrei W.; Feng, Ying; Peng, Xiao; Qiao, Sofie; Post, Leonard
err分享
err收藏
The Hippo pathway protein YAP mediates resistance to MEK1/2 inhibition in neuroblastoma
errCANCER RESEARCH
IF16.6
err2019-07-01
err2
PREAI
errCoggins, Grace E.; Farrel, Alvin; Rathi, Komal; Hayes, Colin M.; Tang, Tracy; Post, Leonard; Maris, John M.
err分享
err收藏
Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer Agent
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2015-12-23
err150
PREAI
errWang, Bing; Chu, Daniel; Feng, Ying; Shen, Yuqiao; Aoyagi-Scharber, Mika; Post, Leonard E.
err分享
err收藏
Potent anti-tumor activity of talazoparib (BMN673) in combination with radiation for squamous cell carcinoma of the head and neck
errCANCER RESEARCH
IF16.6
err2015-08-01
err0
PREAI
errWong, Deborah J. L.; Shin, David D.; Ratikan, Josephine; Chalukya, Meenal; Manivong, Kanthinh; Post, Leonard; Schaue, Doerthe; Finn, Richard S.; Shen, Yuqiao (Jerry); McBride, William; Slamon, Dennis J.
err分享
err收藏
BMN 673 as single agent and in combination with temozolomide or PI3K pathway inhibitors in small cell lung cancer and gastric cancer models
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2014-11-01
err0
PREAI
errFeng, Y.; Post, L. E.; Cardnell, R.; Byers, L. A.; Wang, B.; Shen, Y.
err分享
err收藏
Selective sensitivity of Ewing's Sarcoma to the PARP inhibitor BMN 673
errCANCER RESEARCH
IF16.6
err2013-04-01
err0
PREAI
errSingh, Arun; Chmielowski, Bartosz; Jia, Weiping; Clarke, Kareem; O'Brien, Neil; Dering, Judy; Conklin, Dylan; Shen, Yuqiao; Post, Leonard; Finn, Richard S.; Slamon, Dennis J.
err分享
err收藏
Novel PARP inhibitors with potent antitumor activity as single-agent and combination therapies
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2009-12-01
err7
PREAI
errWang, Bing; Chu, Daniel; Feng, Ying; Yu, Xin; Myers, Peter; Post, Leonard; Shen, Yucliao (Jerry)
err分享
err收藏

研究方向

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合作学者
合作期刊
管坤良 封面图
管坤良 (Kun‐Liang Guan)
H 指数: 168 · 论文数: 623
G
GutkindJ.Silvio (J. Silvio Gutkind)
H 指数: 140 · 论文数: 1.3K
F
Frank McCormick
H 指数: 130 · 论文数: 788
C
Channing J. Der
H 指数: 127 · 论文数: 1.0K
D
Dennis J. Slamon
H 指数: 126 · 论文数: 986
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