Michael J. Weber - Publications, H-index & Citations

Michael J. Weber

University of Virginia

71H指数

296论文数

2.0W被引数

收录论文 46

发表时间

PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-07-03

OAAI

Jayappa, Kallesh D.; Tran, Brian; Gordon, Vicki L.; Morris, Christopher; Saha, Shekhar; Farrington, Caroline C.; O'Connor, Caitlin M.; Zawacki, Kaitlin P.; Isaac, Krista M.; Kester, Mark; Bender, Timothy P.; Williams, Michael E.; Portell, Craig A.; Weber, Michael J.; Narla, Goutham

Rac-PAK signaling stimulates extracellular signal- regulated kinase (ERK) activation by regulating formation of MEKI-ERK complexes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-30

234

OAAI

Eblen, ST; Slack, JK; Weber, MJ; Catling, AD

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt 胰岛素样生长因子I受体，磷脂酰肌醇3-激酶和Akt的抗凋亡信号传导

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

1.1K

OAAI

Kulik, G; Klippel, A; Weber, MJ

Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

236

OAAI

Kulik, G; Weber, MJ

Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Eblen, ST; Catling, AD; Assanah, MC; Weber, MJ

RACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motility

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Vomastek, Tomas; Iwanicki, Marcin P.; Schaeffer, Hans-Joerg; Tarcsafalvi, Adel; Parsons, J. Thomas; Weber, Michael J.

Extracellular Signal-Regulated Kinase 2 (ERK2) Phosphorylation Sites and Docking Domain on the Nuclear Pore Complex Protein Tpr Cooperatively Regulate ERK2-Tpr Interaction

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Vomastek, Tomas; Iwanicki, Marcin P.; Burack, W. Richard; Tiwari, Divya; Kumar, Devanand; Parsons, J. Thomas; Weber, Michael J.; Nandicoori, Vinay Kumar

Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

138

OAAI

Eblen, ST; Slack-Davis, JK; Tarcsafalvi, A; Parsons, JT; Weber, MJ; Catling, AD

Extrinsic interactions in the microenvironment in vivo activate an antiapoptotic multidrug-resistant phenotype in CLL

BLOOD ADVANCES

IF7.1

2021-09-13

OAAI

Jayappa, Kallesh D.; Gordon, Vicki L.; Morris, Christopher G.; Wilson, Briana; Shetty, B. Dharmaveer; Cios, Konrad J.; Arora, Puja C.; Isaac, Krista M.; Saha, Shekhar; Bender, Timothy P.; Williams, Michael E.; Portell, Craig A.; Weber, Michael J.

Loss of S6K2 perturbs redox balance and fatty acid metabolism, leading to oxidative cell death

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Chen, Hsin-Yi; Samanta, Minu; Reyes-Uribe, Patricia; Kossenkov, Andrew V.; Yin, Xiangfan; Lu, Yiling; Axelrod, Mark; Weber, Michael J.; Liu, Qin; Mills, Gordon B.; Villanueva, Jessie

Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha

NEURO-ONCOLOGY

IF13.4

2017-06-29

OAAI

Olmez, Inan; Love, Shawn; Xiao, Aizhen; Manigat, Laryssa; Randolph, Peyton; McKenna, Brian D.; Neal, Brian P.; Boroda, Salome; Li, Ming; Brenneman, Breanna; Abounader, Roger; Floyd, Desiree; Lee, Jeongwu; Nakano, Ichiro; Godlewski, Jakub; Bronisz, Agnieszka; Sulman, Erik P.; Mayo, Marty; Gioeli, Daniel; Weber, Michael; Harris, Thurl E.; Purow, Benjamin

Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL

BLOOD ADVANCES

IF7.1

2017-06-07

OAAI

Jayappa, Kallesh D.; Portell, Craig A.; Gordon, Vicki L.; Capaldo, Brian J.; Bekiranov, Stefan; Axelrod, Mark J.; Brett, L. Kyle; Wulfkuhle, Julia D.; Gallagher, Rosa I.; Petricoin, Emanuel F.; Bender, Timothy P.; Williams, Michael E.; Weber, Michael J.

The state of melanoma: challenges and opportunities 黑色素瘤的现状: 挑战与机遇

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2016-04-17

OAAI

Merlino, Glenn; Herlyn, Meenhard; Fisher, David E.; Bastian, Boris C.; Flaherty, Keith T.; Davies, Michael A.; Wargo, Jennifer A.; Curiel-Lewandrowski, Clara; Weber, Michael J.; Leachman, Sancy A.; Soengas, Maria S.; McMahon, Martin; Harbour, J. William; Swetter, Susan M.; Aplin, Andrew E.; Atkins, Michael B.; Bosenberg, Marcus W.; Dummer, Reinhard; Gershenwald, Jeffrey E.; Halpern, Allan C.; Herlyn, Dorothee; Karakousis, Giorgos C.; Kirkwood, John M.; Krauthammer, Michael; Lo, Roger S.; Long, Georgina V.; McArthur, Grant; Ribas, Antoni; Schuchter, Lynn; Sosman, Jeffrey A.; Smalley, Keiran S.; Steeg, Patricia; Thomas, Nancy E.; Tsao, Hensin; Tueting, Thomas; Weeraratna, Ashani; Xu, George; Lomax, Randy; Martin, Alison; Silverstein, Steve; Turnham, Tim; Ronai, Ze'ev A.

Integrin adjunct therapy for melanoma

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2014-11-03

OAAI

Andarawewa, Kumari L.; Moissoglu, Konstadinos; Lee, Chang Sup; Ando, Yuta; Yu, Min; Debnath, Prianka; Shannon, John D.; Sirinivasan, Suseela; Conaway, Mark R.; Weber, Michael J.; Schwartz, Martin A.

p70S6 kinase is a critical node that integrates HER-family and PI3 kinase signaling

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Axelrod, Mark J.; Mendez, Rolando E.; Gioeli, Daniel G.; Jameson, Mark J.; Weber, Michael J.

Integrated molecular profiling of melanoma cell lines reveals genotype-drug phenotype associations giving insight on development of combination therapies

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Capaldo, Brian J.; Roller, Devin G.; Axelrod, Mark; Koeppel, Alex; Weber, Michael J.; Mackey, Aaron; Gioeli, Dan; Bekiranov, Stefan

p70S6 kinase is a critical node that integrates HER-family and PI3 kinase signaling networks

CELLULAR SIGNALLING

IF3.7

2014-08-01

OAAI

Axelrod, Mark J.; Gordon, Vicki; Mendez, Rolando E.; Leimgruber, Stephanie S.; Conaway, Mark R.; Sharlow, Elizabeth R.; Jameson, Mark J.; Gioeli, Daniel G.; Weber, Michael J.

Combinatorial screens with targeted inhibitors reveal diverse compensatory responses and mechanisms of adaptive resistance to therapy

MOLECULAR CANCER THERAPEUTICS

IF5.5

2014-05-01

PREAI

Axelrod, Mark J.; Roller, Devin; Capaldo, Brian; Mackey, Aaron J.; Conaway, Mark; Gioeli, Daniel; Weber, Michael J.

Combinatorial drug screening identifies synergistic co-targeting of Bruton's tyrosine kinase and the proteasome in mantle cell lymphoma

LEUKEMIA

IF13.4

2013-08-27

OAAI

Axelrod, M.; Ou, Z.; Brett, L. K.; Zhang, L.; Lopez, E. R.; Tamayo, A. T.; Gordon, V.; Ford, R. J.; Williams, M. E.; Pham, L. V.; Weber, M. J.; Wang, M. L.

Co-targeting the IGF1R pathway and compensatory signaling enhances cytotoxicity in head and neck cancer

CANCER RESEARCH

IF16.6

2013-04-01

PREAI

Axelrod, Mark J.; Gioeli, Daniel; Sharlow, Elizabeth R.; Conaway, Mark C.; Mendez, Rolando E.; Khalil, Ashraf; Taniguchi, Linnea; Petricoin, Emmanual F.; Leimgruber, Stephanie; Weber, Michael J.; Jameson, Mark J.

研究方向