Domenico Accili - Publications, H-index & Citations

Domenico Accili

Columbia University

101H指数

360论文数

4.8W被引数

收录论文 175

发表时间

Tuning insulin receptor signaling using de novo-designed agonists 使用从头设计的激动剂调节胰岛素受体信号传导

Molecular Cell

IF16.6

2025-10-13

OAAI

Xinru Wang; Sarah Cardoso; Kai Cai; Preetham Venkatesh; Albert Hung; Michelle Ng; Catherine Hall; Brian Coventry; David S. Lee; Rishabh Chowhan; Stacey Gerben; Jie Li; Weidong An; Mara Hon; Michael Gao; Ya-Cheng Liao; Domenico Accili; Eunhee Choi; Xiao-chen Bai; David Baker

Insulin Resistance in Type 1 Diabetes: Concepts and Implications for Therapy 1型糖尿病中的胰岛素抵抗：概念及其对治疗的启示

Journal of Diabetes

IF3.7

2025-07-18

OAAI

Zachary Bloomgarden; Domenico Accili

Insulin resistance in type 2 diabetes mellitus 2型糖尿病中的胰岛素抵抗

nature reviews endocrinology

IF40

2025-04-17

PREAI

Accili, Domenico; Deng, Zhaobing; Liu, Qingli

Dedifferentiation as a Stealthy Disruptor of β-Cell Function in Diabetes 去分化是糖尿病中 β 细胞功能的隐形干扰物

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2024-09-11

OAAI

Son, Jinsook; Accili, Domenico

Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells

JOURNAL OF CELL BIOLOGY

IF6.4

2024-07-03

OAAI

McKimpson, Wendy M.; Spiegel, Sophia; Mukhanova, Maria; Kraakman, Michael; Du, Wen; Kitamoto, Takumi; Yu, Junjie; Deng, Zhaobin; Pajvani, Utpal; Accili, Domenico

Foxo3 and Heterogeneity of Dedifferentiating β-Cells

DIABETES

IF7.5

2024-06-14

PREAI

Son, Jinsook; Accili, Domenico

(3-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice

MOLECULAR METABOLISM

IF6.6

2024-03-01

OAAI

Suda, Nina; Bartolome, Alberto; Liang, Jiani; Son, Jinsook; Yagishita, Yoko; Siebel, Christian; Accili, Domenico; Ding, Hongxu; Pajvani, Utpal B.

Diabetes treatment by conversion of gut epithelial cells to insulin-producing cells

JOURNAL OF DIABETES INVESTIGATION

IF3

2024-03-01

OAAI

Accili, Domenico; Talchai, Shivatra C.; Bouchi, Ryotaro; Lee, April Yun-Kyoung; Du, Wen; Kitamoto, Takumi; McKimpson, Wendy M.; Belvedere, Sandro; Lin, Hua, V

Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner (17, 8, 2011)

NATURE MEDICINE

IF50

2023-12-01

OAAI

Pajvani, Utpal B.; Shawber, Carrie J.; Samuel, Varman T.; Birkenfeld, Andreas L.; Shulman, Gerald I.; Kitajewski, Jan; Accili, Domenico

MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis

DIABETES

IF7.5

2023-09-19

OAAI

Park, Junhee; Hall, Catherine; Hubbard, Brandon; LaMoia, Traci; Gaspar, Rafael; Nasiri, Ali; Li, Fang; Zhang, Hanrui; Kim, Jiyeon; Haeusler, Rebecca A.; Accili, Domenico; Shulman, Gerald I.; Yu, Hongtao; Choi, Eunhee

Reversing pancreatic β-cell dedifferentiation in the treatment of type 2 diabetes

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2023-08-01

OAAI

Son, Jinsook; Accili, Domenico

Preserved pancreatic β-cell development and function in mice lacking the insulin receptor-related receptor

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Kitamura, T; Kido, Y; Nef, S; Merenmies, J; Parada, LF; Accili, D

Regulation of Pancreatic Juxtaductal Endocrine Cell Formation by FoxO1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Kitamura, Tadahiro; Kitamura, Yukari Ido; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; DePinho, Ronald A.; Accili, Domenico

PPARγ (Peroxisome Proliferator-Activated Receptor γ) Deacetylation Suppresses Aging-Associated Atherosclerosis and Hypercholesterolemia

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2023-01-01

OAAI

Zahr, Tarik; Liu, Longhua; Chan, Michelle; Zhou, Qiuzhong; Cai, Bishuang; He, Ying; Aaron, Nicole; Accili, Domenico; Sun, Lei; Qiang, Li

Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2022-12-15

OAAI

Du, Wen; Wang, Junqiang; Kuo, Taiyi; Wang, Liheng; McKimpson, Wendy M.; Son, Jinsook; Watanabe, Hitoshi; Kitamoto, Takumi; Lee, Yunkyoung; Creusot, Remi J.; Ratner, Lloyd E.; McCune, Kasi; Chen, Ya-Wen; Grubbs, Brendan H.; Thornton, Matthew E.; Fan, Jason; Sultana, Nishat; Diaz, Bryan S.; Balasubramanian, Iyshwarya; Gao, Nan; Belvedere, Sandro; Accili, Domenico

Chemical induction of gut ? -like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes

MOLECULAR METABOLISM

IF6.6

2022-12-01

OAAI

Kitamoto, Takumi; Lee, Yun-Kyoung; Sultana, Nishat; Watanabe, Hitoshi; McKimpson, Wendy M.; Du, Wen; Fan, Jason; Diaz, Bryan; Lin, Hua V.; Leibel, Rudolph L.; Belvedere, Sandro; Accili, Domenico

Single-agent FOXO1 inhibition normalizes glycemia and induces gut 0-like cells in streptozotocin-diabetic mice

MOLECULAR METABOLISM

IF6.6

2022-12-01

OAAI

Lee, Yun-Kyoung; Du, Wen; Nie, Yaohui; Diaz, Bryan; Sultana, Nishat; Kitamoto, Takumi; Leibel, Rudolph L.; Accili, Domenico; Belvedere, Sandro

Susumu Seino, MD, DMSci (1948-2021): A Pioneer in the Biology of Insulin Secretion

DIABETES

IF7.5

2022-11-21

OAAI

Accili, Domenico; Bell, Graeme I.; Thorens, Bernard

Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice

NATURE COMMUNICATIONS

IF15.7

2022-10-05

OAAI

Sasako, Takayoshi; Umehara, Toshihiro; Soeda, Kotaro; Kaneko, Kazuma; Suzuki, Miho; Kobayashi, Naoki; Okazaki, Yukiko; Tamura-Nakano, Miwa; Chiba, Tomoki; Accili, Domenico; Kahn, C. Ronald; Noda, Tetsuo; Asahara, Hiroshi; Yamauchi, Toshimasa; Kadowaki, Takashi; Ueki, Kohjiro

Activation of the insulin receptor by an insulin mimetic peptide

NATURE COMMUNICATIONS

IF15.7

2022-09-23

OAAI

Park, Junhee; Li, Jie; Mayer, John P.; Ball, Kerri A.; Wu, Jiayi; Hall, Catherine; Accili, Domenico; Stowell, Michael H. B.; Bai, Xiao-chen; Choi, Eunhee

研究方向