未登录 Autologous Thymic Organoids Support Functional T-cell Education and Enhance Antitumor Immunity in Humanized Mice with Melanoma Xenografts Morton, J. Jason; Ramos, Stephan A.; Alzofon, Nathaniel; Keysar, Stephen B.; Armitage, Lucas H.; Baker, Alexander S.; Barra, Jessie M.; Chimed, Tugs-Saikhan; Le, Phuong N.; Nieto, Cera; Weaver, Alice N.; Thomas, Carissa M.; Miller, Bettina; Robinson, William; Medina, Theresa M.; Gao, Dexiang; Russ, Holger A.; Jimeno, Antonio 分享 收藏
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Safety, tolerability, and efficacy of nadunolimab in combination with pembrolizumab in patients with solid tumors 纳武利尤单抗与帕博利珠单抗联合治疗实体瘤患者的安全性、耐受性及疗效 Cohen, R.; Jauhari, S.; Jimeno, A.; Hreno, J.; Sun, L.; Ohman, M. Wallen; Sanfridson, A.; Losic, N.; Tersago, D. 分享 收藏
First-in-human, phase I/II, monotherapy, dose-escalation study of mRNA-4359, an mRNA-encoded PD-L1/IDO1 antigen-specific therapy, in advanced/refractory solid tumors 首次人体研究，I/II期，单药治疗，剂量递增研究，针对mRNA-4359（一种mRNA编码的PD-L1/IDO1抗原特异性疗法）在晚期/难治性实体瘤中的应用 Khattak, M. A.; Sullivan, R. J.; Gutierrez, M.; Jimeno, A.; Thomas, S. S.; Long, G. V.; Kummar, S.; Daud, A.; Rohatgi, A.; Sweis, R. F.; Bauman, J. E.; Boni, V.; Parakh, S.; Daghestani, H. N.; Xu, J.; Li, Y.; Morrissey, M.; Abadier, M.; Barlaskar, F.; Sarker, D. 分享 收藏
Histone-methyltransferase KMT2D deficiency impairs the Fanconi anemia/BRCA pathway upon glycolytic inhibition in squamous cell carcinoma Liu, Wei; Cao, Hongchao; Wang, Jing; Elmusrati, Areeg; Han, Bing; Chen, Wei; Zhou, Ping; Li, Xiyao; Keysar, Stephen; Jimeno, Antonio; Wang, Cun-Yu 分享 收藏
Final outcomes analysis of the cell product SQZ-PBMC-HPV Phase 1 trial in incurable HPV16+solid tumors shows improved overall survival in patients with increased CD8+T cell tumor infiltration Weaver, Alice N.; Iams, Wade T.; Park, Jong Chul; Mita, Monica; Holtick, Udo; Gordon, Michael S.; Rodabaugh, Kerry J.; Dhani, Neesha; Neupane, Prakash; Taylor, Matthew; Amanda Duvall, E.; Jennings, Julia; Miselis, Nathan R.; Loughhead, Scott; Warren, Marshelle S.; Bernstein, Howard; Klussmann, Jens P.; Baranda, Joaquina; Jimeno, Antonio 分享 收藏
Sacituzumab govitecan (SG) in patients (pts) with relapsed/refractory (R/R) advanced head and neck squamous cell carcinoma (HNSCC): Results from the phase II TROPiCS-03 basket trial Michel, L.; Jimeno, A.; Sukari, A.; Beck, T.; Chiu, J. W. Y.; Ahern, E. S.; Hilton, J.; Hollebecque, A.; Zanetta, S.; Patel, J.; Mekan, S.; Wu, T.; Dumbrava, E. E. 分享 收藏
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The programmed death ligand 1 interactome demonstrates bidirectional signaling coordinating immune suppression and cancer progression in head and neck squamous cell carcinoma Nieto, Cera; Miller, Bettina; Alzofon, Nathaniel; Chimed, Tugy; Himes, Jack; Joshi, Molishree; Gomez, Karina; Chowdhury, Farshad N.; Le, Phuong N.; Weaver, Alice; Somerset, Hilary; Morton, J. Jason; Wang, Jing H.; Wang, Xiao-Jing; Gao, Dexiang; Hansen, Kirk; Keysar, Stephen B.; Jimeno, Antonio 分享 收藏
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A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC (vol 3, pg 1300, 2022) Darragh, Laurel B.; Knitz, Michael M.; Hu, Junxiao; Clambey, Eric T.; Backus, Jennifer; Dumit, Andrew; Samedi, Von; Bubak, Andrew; Greene, Casey; Waxweiler, Timothy; Mehrotra, Sanjana; Bhatia, Shilpa; Gadwa, Jacob; Bickett, Thomas; Piper, Miles; Fakhoury, Kareem; Liu, Arthur; Petit, Joshua; Bowles, Daniel; Thaker, Ashesh; Atiyeh, Kimberly; Goddard, Julie; Hoyer, Robert; Van Bokhoven, Adrie; Jordan, Kimberly; Jimeno, Antonio; D'Alessandro, Angelo; Raben, David; McDermott, Jessica D.; Karam, Sana D. 分享 收藏
A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC Darragh, Laurel B.; Knitz, Michael M.; Hu, Junxiao; Clambey, Eric T.; Backus, Jennifer; Dumit, Andrew; Samedi, Von; Bubak, Andrew; Greene, Casey; Waxweiler, Timothy; Mehrotra, Sanjana; Bhatia, Shilpa; Gadwa, Jacob; Bickett, Thomas; Piper, Miles; Fakhoury, Kareem; Liu, Arthur; Petit, Joshua; Bowles, Daniel; Thaker, Ashesh; Atiyeh, Kimberly; Goddard, Julie; Hoyer, Robert; Van Bokhoven, Adrie; Jordan, Kimberly; Jimeno, Antonio; D'Alessandro, Angelo; Raben, David; McDermott, Jessica D.; Karam, Sana D. 分享 收藏
Phase 1 study of the safety, pharmacokinetics, and preliminary efficacy of CA102N as monotherapy and in combination with trifluridine-tipiracil in patients with locally advanced or metastatic solid tumors Pant, Shubham; Dragovich, Tomislav; Lieu, Christopher; Jimeno, Antonio; Kundranda, Madappa; Menter, David; Tchaparian, Eskouhie; Chen, Yuchih C.; Kopetz, Scott 分享 收藏
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Head and Neck Cancers, Version 1.2022 Featured Updates to the NCCN Guidelines 头颈癌，1.2022版更新了NCCN指南 Caudell, Jimmy J.; Gillison, Maura L.; Maghami, Ellie; Spencer, Sharon; Pfister, David G.; Adkins, Douglas; Birkeland, Andrew C.; Brizel, David M.; Busse, Paul M.; Cmelak, Anthony J.; Colevas, A. Dimitrios; Eisele, David W.; Galloway, Thomas; Geiger, Jessica L.; Haddad, Robert, I; Hicks, Wesley L.; Hitchcock, Ying J.; Jimeno, Antonio; Leizman, Debra; Mell, Loren K.; Mittal, Bharat B.; Pinto, Harlan A.; Rocco, James W.; Rodriguez, Cristina P.; Savvides, Panayiotis S.; Schwartz, David; Shah, Jatin P.; Sher, David; St John, Maie; Weber, Randal S.; Weinstein, Gregory; Worden, Frank; Bruce, Justine Yang; Yom, Sue S.; Zhen, Weining; Burns, Jennifer L.; Darlow, Susan D. 分享 收藏
Generation of functional human thymic cells from induced pluripotent stem cells Ramos, Stephan A.; Morton, John J.; Yadav, Prabha; Reed, Brendan; Alizadeh, Sheila, I; Shilleh, Ali H.; Perrenoud, Loni; Jaggers, James; Kappler, John; Jimeno, Antonio; Russ, Holger A. 分享 收藏
Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFβ/PD-L1 blockade-treated squamous cell carcinoma Strait, Alexander A.; Woolaver, Rachel A.; Hall, Spencer C.; Young, Christian D.; Karam, Sana D.; Jimeno, Antonio; Lan, Yan; Raben, David; Wang, Jing H.; Wang, Xiao-Jing 分享 收藏
Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft Morton, J. Jason; Alzofon, Nathaniel; Keysar, Stephen B.; Chimed, Tugs-Saikhan; Reisinger, Julie; Perrenoud, Loni; Le, Phuong N.; Nieto, Cera; Gomez, Karina; Miller, Bettina; Yeager, Randi; Gao, Dexiang; Tan, Aik-Choon; Somerset, Hilary; Medina, Theresa; Wang, Xiao-Jing; Wang, Jing H.; Robinson, William; Roop, Dennis R.; Gonzalez, Rene; Jimeno, Antonio 分享 收藏
Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells Gomez, Karina E.; Wu, FangLong; Keysar, Stephen B.; Morton, J. Jason; Miller, Bettina; Chimed, Tugs-Saikhan; Le, Phuong N.; Nieto, Cera; Chowdhury, Farshad N.; Tyagi, Anit; Lyons, Traci R.; Young, Christian D.; Zhou, Hongmei; Somerset, Hilary L.; Wang, Xiao-Jing; Jimeno, Antonio 分享 收藏
Safety and efficacy of vibostolimab, an anti-TIGIT antibody, plus pembrolizumab in patients with anti-PD-1/PD-L1-naive NSCLC Niu, J.; Nagrial, A.; Voskoboynik, M.; Chung, H. C.; Lee, D. H.; Ahn, M-J.; Bauer, T. M.; Jimeno, A.; Chung, V.; Mileham, K. F.; Chartash, E.; Chen, D.; Healy, J.; Rajasagi, M.; Maurice-Dror, C. 分享 收藏
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