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Thomas R. Kleyman

university of pittsburgh

61H指数
353论文数
1.3W被引数
收录论文 199
发表时间
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Acid-sensing ion channel 2a assembles with epithelial Na+ channel β and γ subunits to form mechanosensitive ion channels酸敏感离子通道2a与上皮钠离子通道β和γ亚基组装形成机械敏感性离子通道
errJournal of Biological Chemistry
IF3.9
err2026-05-14
err0
errOAAI
errShujie Shi; Sarah Christine M. Whelan; Kennedy G. Szekely; Ossama B. Kashlan; Heather Drummond; Thomas R. Kleyman
err分享
err收藏
Resistance to doxorubicin-induced proteinuria and proteolytic activation of ENaC in 129S2/SvPas mice129S2/SvPas小鼠对多柔比星诱导的蛋白尿及ENaC的蛋白酶激活具有抵抗性
errPHYSIOLOGICAL REPORTS
IF1.9
err2025-12-08
err0
errOAAI
errRay, Evan C.; Liu, Ivy; Momenzadeh, Niloofar; Szekely, Kennedy; Marciszyn, Allison L.; Lam, Tracey; Nickerson, Andrew J.; Kleyman, Thomas R.
err分享
err收藏
The scaffold protein IQGAP1 regulates the epithelial Na+ channel支架蛋白IQGAP1调控上皮钠离子通道
errJournal of Biological Chemistry
IF3.9
err2025-11-07
err0
errOAAI
errLouise Thines; Shujie Shi; Samar Sayedyahossein; Zhigang Li; Francis J. Roushar; Thomas R. Kleyman; David B. Sacks
err分享
err收藏
Paraoxonase 3 regulates the pore-forming α subunit of the large-conductance K plus channelParaoxonase 3 调节大电导钾离子通道的成孔α亚基
errBIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
IF3.7
err2025-06-03
err0
errOAAI
errWhelan, Sarah Christine M.; Nickerson, Andrew J.; Montalbetti, Nicolas; Mutchler, Stephanie M.; Carattino, Marcelo D.; Kleyman, Thomas R.; Shi, Shujie
err分享
err收藏
Population Health Management for Improving Kidney Health Outcomes以改善肾脏健康结局的全民健康管理
errAmerican Journal of Kidney Diseases
IF8.2
err2025-03-17
err0
errOAAI
errManisha Jhamb; Jane O. Schell; Melanie R. Weltman; Linda-Marie U. Lavenburg; Chethan Puttarajappa; Gary S. Fischer; Thomas Kleyman
err分享
err收藏
Effect of sex chromosome complement versus gonadal hormones on abundance of renal transporters性染色体组成与性腺激素对肾脏转运蛋白丰度的影响
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2025-03-10
err0
PREAI
errMcdonough, Alicia A.; Foley, Trinity S.; Ralph, Donna L.; Schwindt, Seth; Soong, Joanne; Carrisoza-Gaytan, Rolando; Lasaad, Samia; Nelson, Jonathan W.; Edwards, Aurelie; Kleyman, Thomas R.; Satlin, Lisa M.
err分享
err收藏
Excess dietary sodium restores electrolyte and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron饮食中过量的钠可恢复小鼠肾单位中内质网分子伴侣GRP170丢失引起的电解质和水稳态
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2025-02-01
err0
PREAI
errPorter, Aidan W.; Vorndran, Hannah E.; Marciszyn, Allison; Mutchler, Stephanie M.; Subramanya, Arohan R.; Kleyman, Thomas R.; Hendershot, Linda M.; Brodsky, Jeffrey L.; Buck, Teresa M.
err分享
err收藏
Expression and distribution of MUC1 in the developing and adult kidneyMUC1在发育和成年肾脏中的表达和分布
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2025-01-01
err0
PREAI
errManrique-Caballero, Carlos L.; Barasch, Jonathan; Zaidi, Syed K.; Bates, Carlton M.; Ray, Evan C.; Kleyman, Thomas R.; Al-Bataineh, Mohammad M.
err分享
err收藏
Canagliflozin Inhibits Electrogenic Na+ Transport in Mouse Cortical Collecting Duct Cells卡格列净抑制小鼠皮质集合管细胞中电生性Na+转运
errFUNCTION
IF3.8
err2025-01-01
err0
errOAAI
errNickerson, Andrew J.; Albalawy, Wafaa N.; Youm, Elynna B.; Joseph, Nicole A.; Szekely, Kennedy G.; Kleyman, Thomas R.; Weisz, Ora A.; Kashlan, Ossama B.
err分享
err收藏
Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure骨髓特异性JAK2有助于血压的炎症和盐敏感性
errCIRCULATION RESEARCH
IF16.2
err2024-10-11
err3
PREAI
errSaleem, Mohammad; Aden, Luul A.; Mutchler, Ashley L.; Basu, Chitra; Ertuglu, Lale A.; Sheng, Quanhu; Penner, Niki; Hemnes, Anna R.; Park, Jennifer H.; Ishimwe, Jeanne A.; Laffer, Cheryl L.; Elijovich, Fernando; Wanjalla, Celestine N.; de la Visitacion, Nestor; Kastner, Paul D.; Albritton, Claude F.; Ahmad, Taseer; Haynes, Alexandria P.; Yu, Justin; Graber, Meghan K.; Yasmin, Sharia; Wagner, Kay-Uwe; Sayeski, Peter P.; Hatzopoulos, Antonis K.; Gamazon, Eric R.; Bick, Alexander G.; Kleyman, Thomas R.; Kirabo, Annet
err分享
err收藏
Characterization of hyperactive mutations in the renal potassium channel ROMK uncovers unique effects on channel biogenesis and ion conductance
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2024-09-01
err1
errOAAI
errNguyen, Nga H.; Sheng, Shaohu; Banerjee, Anupam; Guerriero, Christopher J.; Chen, Jingxin; Wang, Xueqi; Mackie, Timothy D.; Welling, Paul A.; Kleyman, Thomas R.; Bahar, Ivet; Carlson, Anne E.; Brodsky, Jeffrey L.
err分享
err收藏
Kcnma1 alternative splicing in mouse kidney: regulation during development and by dietary K+ intake
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2024-07-01
err1
PREAI
errWhelan, Sarah Christine M.; Mutchler, Stephanie M.; Han, Agnes; Priestley, Catherine; Satlin, Lisa M.; Kleyman, Thomas R.; Shi, Shujie
err分享
err收藏
Influence of proteolytic cleavage of ENaC's γ subunit upon Na+ and K+ handling
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2024-06-01
err5
PREAI
errRay, Evan C.; Nickerson, Andrew; Sheng, Shaohu; Carrisoza-Gaytan, Rolando; Lam, Tracey; Marciszyn, Allison; Zhang, Lei; Jordahl, Alexa; Bi, Chunming; Winfrey, Aaliyah; Kou, Zhaohui; Gingras, Sebastien; Kirabo, Annet; Satlin, Lisa M.; Kleyman, Thomas R.
err分享
err收藏
Cannabinoid receptor type 1 activation causes a water diuresis by inducing an acute central diabetes insipidus in mice
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2024-06-01
err1
PREAI
errRein, Joshua L.; Mackie, Ken; Kleyman, Thomas R.; Satlin, Lisa M.
err分享
err收藏
Epithelial Na+ Channels Function as Extracellular Sensors上皮Na通道作为细胞外传感器
errCOMPREHENSIVE PHYSIOLOGY
IF5.2
err2024-03-29
err7
PREAI
errKashlan, Ossama B.; Wang, Xue-Ping; Sheng, Shaohu; Kleyman, Thomas R.
err分享
err收藏
Eicosanoid-Regulated Myeloid ENaC and Isolevuglandin Formation in Human Salt-Sensitive Hypertension在人类盐敏感性高血压中，类胡萝卜素调节的骨髓ENaC和异甘兰素的形成
errHYPERTENSION
IF8.2
err2024-03-01
err10
PREAI
errErtuglu, Lale A.; Mutchler, Ashley Pitzer; Jamison, Sydney; Laffer, Cheryl L.; Elijovich, Fernando; Saleem, Mohammad; Blackwell, Daniel J.; Kryshtal, Dmytro O.; Egly, Christian L.; Sahinoz, Melis; Sheng, Quanhu; Wanjalla, Celestine N.; Pakala, Suman; Yu, Justin; Gutierrez, Orlando M.; Kleyman, Thomas R.; Knollmann, Bjoern C.; Ikizler, T. Alp; Kirabo, Annet
err分享
err收藏
PIEZO1 is a distal nephron mechanosensor and is required for flow-induced K plus secretion
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-03-01
err7
errOAAI
errCarrisoza-Gaytan, Rolando; Mutchler, Stephanie M.; Carattino, Francisco; Soong, Joanne; Dalghi, Marianela G.; Wu, Peng; Wang, WenHui; Apodaca, Gerard; Satlin, Lisa M.; Kleyman, Thomas R.
err分享
err收藏
Genome mining yields putative disease-associated ROMK variants with distinct defects基因组挖掘产生具有明显缺陷的推定疾病相关ROMK变体
errPLOS GENETICS
IF3.7
err2023-11-13
err2
errOAAI
errNguyen, Nga H.; Sarangi, Srikant; Mcchesney, Erin M.; Sheng, Shaohu; Durrant, Jacob D.; Porter, Aidan W.; Kleyman, Thomas R.; Pitluk, Zachary W.; Brodsky, Jeffrey L.
err分享
err收藏
Mice lacking γENaC palmitoylation sites maintain benzamil-sensitive Na plus transport despite reduced channel activity
errJCI INSIGHT
IF6.1
err2023-11-08
err4
errOAAI
errNickerson, Andrew J.; Mutchler, Stephanie M.; Sheng, Shaohu; Cox, Natalie A.; Ray, Evan C.; Kashlan, Ossama B.; Carattino, Marcelo D.; Marciszyn, Allison L.; Winfrey, Aaliyah; Gingras, Sebastien; Kirabo, Annet; Hughey, Rebecca P.; Kleyman, Thomas R.
err分享
err收藏
Lhs1 dependent ERAD is determined by transmembrane domain context
errBIOCHEMICAL JOURNAL
IF4.3
err2023-09-21
err4
errOAAI
errSukhoplyasova, Maria; Keith, Abigail M.; Perrault, Emma M.; Vorndran, Hannah E.; Jordahl, Alexa S.; Yates, Megan E.; Pastor, Ashutosh; Li, Zachary; Freaney, Michael L.; Deshpande, Riddhi A.; Adams, David B.; Guerriero, Christopher J.; Shi, Shujie; Kleyman, Thomas R.; Kashlan, Ossama B.; Brodsky, Jeffrey L.; Buck, Teresa M.
err分享
err收藏

研究方向

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