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A deep learning approach predicting the activity of COVID-19 therapeutics and vaccines against emerging variants Matson, Robert P.; Comba, Isin Y.; Silvert, Eli; Niesen, Michiel J. M.; Murugadoss, Karthik; Patwardhan, Dhruti; Suratekar, Rohit; Goel, Elizabeth-Grace; Poelaert, Brittany J.; Wan, Kanny K.; Brimacombe, Kyle R.; Venkatakrishnan, A. J.; Soundararajan, Venky 分享 收藏
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics (vol 14, 2138, 2023) Xu, Xinyu; Shonberg, Jeremy; Kaindl, Jonas; Clark, Mary J.; Stoessel, Anne; Maul, Luis; Mayer, Daniel; Huebner, Harald; Hirata, Kunio; Venkatakrishnan, A. J.; Dror, Ron O.; Kobilka, Brian K.; Sunahara, Roger K.; Liu, Xiangyu; Gmeiner, Peter 分享 收藏
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics 受约束的儿茶酚胺通过对口袋动力学的变构作用获得 β2AR选择性 Xu, Xinyu; Shonberg, Jeremy; Kaindl, Jonas; Clark, Mary J. J.; Stoessel, Anne; Maul, Luis; Mayer, Daniel; Huebner, Harald; Hirata, Kunio; Venkatakrishnan, A. J.; Dror, Ron O. O.; Kobilka, Brian K. K.; Sunahara, Roger K. K.; Liu, Xiangyu; Gmeiner, Peter 分享 收藏
Expanding repertoire of SARS-CoV-2 deletion mutations contributes to evolution of highly transmissible variants Venkatakrishnan, A. J.; Anand, Praveen; Lenehan, Patrick J.; Ghosh, Pritha; Suratekar, Rohit; Silvert, Eli; Pawlowski, Colin; Siroha, Abhishek; Chowdhury, Dibyendu Roy; O'Horo, John C.; Yao, Joseph D.; Pritt, Bobbi S.; Norgan, Andrew P.; Hurt, Ryan T.; Badley, Andrew D.; Halamka, John; Soundararajan, Venky 分享 收藏
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Durability analysis of the highly effective BNT162b2 vaccine against COVID-19 Puranik, Arjun; Lenehan, Patrick J.; O'Horo, John C.; Pawlowski, Colin; Niesen, Michiel J. M.; Virk, Abinash; Swift, Melanie D.; Kremers, Walter; Venkatakrishnan, A. J.; Gordon, Joel E.; Geyer, Holly L.; Speicher, Leigh Lewis; Soundararajan, Venky; Badley, Andrew D. 分享 收藏
Durability analysis of the highly effective mRNA-1273 vaccine against COVID-19 新型冠状病毒肺炎高效mRNA-1273疫苗的持久性分析 Puranik, Arjun; Lenehan, Patrick J.; O'Horo, John C.; Pawlowski, Colin; Virk, Abinash; Swift, Melanie D.; Kremers, Walter; Venkatakrishnan, A. J.; Challener, Doug W.; Breeher, Laura; Gordon, Joel E.; Geyer, Holly L.; Speicher, Leigh Lewis; Soundararajan, Venky; Badley, Andrew D. 分享 收藏
Third dose vaccination with mRNA-1273 or BNT162b2 vaccines improves protection against SARS-CoV-2 infection mRNA-1273或BNT162b2疫苗的第三剂疫苗接种可改善对SARS-CoV-2感染的保护 Niesen, Michiel J. M.; Matson, Robert; Puranik, Arjun; O'Horo, John C.; Pawlowski, Colin; Vachon, Celine; Challener, Douglas; Virk, Abinash; Swift, Melanie; Speicher, Leigh; Gordon, Joel; Geyer, Holly; Lenehan, Patrick J.; Venkatakrishnan, A. J.; Soundararajan, Venky; Badley, Andrew 分享 收藏
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Comparative effectiveness of mRNA-1273 and BNT162b2 against symptomatic SARS-CoV-2 infection Puranik, Arjun; Lenehan, Patrick J.; Silvert, Eli; Niesen, Michiel J. M.; Corchado-Garcia, Juan; O'Horo, John C.; Virk, Abinash; Swift, Melanie D.; Gordon, Joel E.; Speicher, Leigh Lewis; Geyer, Holly L.; Kremers, Walter; Halamka, John; Badley, Andrew D.; Venkatakrishnan, A. J.; Soundararajan, Venky 分享 收藏
Casirivimab-Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19 Razonable, Raymund R.; Pawlowski, Colin; O'Horo, John C.; Arndt, Lori L.; Arndt, Richard; Bierle, Dennis M.; Borgen, Molly Destro; Hanson, Sara N.; Hedin, Michelle C.; Lenehan, Patrick; Puranik, Arjun; Seville, Maria T.; Speicher, Leigh L.; Tulledge-Scheitel, Sidna M.; Venkatakrishnan, A. J.; Wilker, Caroline G.; Badley, Andrew D.; Ganesh, Ravindra 分享 收藏
Intravenous bamlanivimab use associates with reduced hospitalization in high-risk patients with mild to moderate COVID-19 Ganesh, Ravindra; Pawlowski, Colin F.; O'Horo, John C.; Arndt, Lori L.; Arndt, Richard F.; Bell, Sarah J.; Bierle, Dennis M.; Borgen, Molly Destro; Hanson, Sara N.; Heyliger, Alexander; Larsen, Jennifer J.; Lenehan, Patrick J.; Orenstein, Robert; Puranik, Arjun; Speicher, Leigh L.; Tulledge-Scheitel, Sidna M.; Venkatakrishnan, A. J.; Wilker, Caroline G.; Badley, Andrew D.; Razonable, Raymund R. 分享 收藏
Real-time analysis of a mass vaccination effort confirms the safety of FDA-authorized mRNA COVID-19 vaccines McMurry, Reid; Lenehan, Patrick; Awasthi, Samir; Silvert, Eli; Puranik, Arjun; Pawlowski, Colin; Venkatakrishnan, A. J.; Anand, Praveen; Agarwal, Vineet; O'Horo, John C.; Gores, Gregory J.; Williams, Amy W.; Badley, Andrew D.; Halamka, John; Virk, Abinash; Swift, Melanie D.; Carlson, Katie; Doddahonnaiah, Deeksha; Metzger, Anna; Kayal, Nikhil; Berner, Gabi; Ramudu, Eshwan; Carpenter, Corinne; Wagner, Tyler; Rajasekharan, Ajit; Soundararajan, Venky 分享 收藏
FDA-authorized mRNA COVID-19 vaccines are effective per real-world evidence synthesized across a mufti-state health system Pawlowski, Colin; Lenehan, Patrick; Puranik, Arjun; Agarwal, Vineet; Venkatakrishnan, A. J.; Niesen, Michiel J. M.; O'Horo, John C.; Virk, Abinash; Swift, Melanie D.; Badley, Andrew D.; Halamka, John; Soundararajan, Venky 分享 收藏
Mapping each pre-existing condition's association to short-term and long-term COVID-19 complications Venkatakrishnan, Aj; Pawlowski, Colin; Zemmour, David; Hughes, Travis; Anand, Akash; Berner, Gabriela; Kayal, Nikhil; Puranik, Arjun; Conrad, Ian; Bade, Sairam; Barve, Rakesh; Sinha, Purushottam; O'Horo, John C.; Badley, Andrew D.; Soundararajan, Venky; Halamka, John 分享 收藏
Pre-existing conditions are associated with COVID-19 patients' hospitalization, despite confirmed clearance of SARS-CoV-2 virus Pawlowski, Colin; Venkatakrishnan, A. J.; Ramudu, Eshwan; Kirkup, Christian; Puranik, Arjun; Kayal, Nikhil; Berner, Gabriela; Anand, Akash; Barve, Rakesh; O'Horo, John C.; Badley, Andrew D.; Soundararajan, Venky 分享 收藏
Healthcare disparities among anticoagulation therapies for severe COVID-19 patients in the multi-site VIRUS registry Kirkup, Christian; Pawlowski, Colin; Puranik, Arjun; Conrad, Ian; O'Horo, John C.; Gomaa, Dina; Banner-Goodspeed, Valerie M.; Mosier, Jarrod M.; Zabolotskikh, Igor Borisovich; Daugherty, Steven K.; Bernstein, Michael A.; Zaren, Howard A.; Bansal, Vikas; Pickering, Brian; Badley, Andrew D.; Kashyap, Rahul; Venkatakrishnan, A. J.; Soundararajan, Venky 分享 收藏
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