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Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model (vol 41, pg 223, 2024) Bodenlenz, Manfred; Yeoh, Thean; Berstein, Gabriel; Mathew, Shibin; Shah, Jaymin; Banfield, Christopher; Hollingshead, Brett; Steyn, Stefanus J.; Osgood, Sarah M.; Beaumont, Kevin; Kainz, Sonja; Holecek, Christian; Trausinger, Gert; Raml, Reingard; Birngruber, Thomas 分享 收藏
Baseline Serum and Stool Microbiome Biomarkers Predict Clinical Efficacy and Tissue Molecular Response After Ritlecitinib Induction Therapy in Ulcerative Colitis Hassan-Zahraee, Mina; Ye, Zhan; Xi, Li; Dushin, Elizabeth; Lee, Julie; Romatowski, Jacek; Leszczyszyn, Jaroslaw; Danese, Silvio; Sandborn, William J.; Banfield, Christopher; Gale, Jeremy D.; Peeva, Elena; Longman, Randy S.; Hyde, Craig L.; Hung, Kenneth E. 分享 收藏
Oral Ritlecitinib and Brepocitinib for Moderate-to-Severe Ulcerative Colitis: Results From a Randomized, Phase 2b Study Sandborn, William J.; Danese, Silvio; Leszczyszyn, Jaroslaw; Romatowski, Jacek; Altintas, Engin; Peeva, Elena; Hassan-Zahraee, Mina; Vincent, Michael S.; Reddy, Padmalatha S.; Banfield, Christopher; Salganik, Mikhail; Banerjee, Anindita; Gale, Jeremy D.; Hung, Kenneth E. 分享 收藏
A phase 1 study to investigate the absorption, distribution, metabolism and excretion of brepocitinib in healthy males using a 14C-microdose approach Qiu, Ruolun; Sharma, Raman; Wei, Hua; Kirkovsky, Leonid; Zhou, Yifan; Martin, David D. A.; Banfield, Christopher; Dowty, Martin E. 分享 收藏
Efficacy and safety of topical brepocitinib cream for mild-to-moderate chronic plaque psoriasis: a phase IIb randomized double-blind vehicle-controlled parallel-group study Landis, Megan N.; Smith, Stacy R.; Berstein, Gabriel; Fetterly, Gerald; Ghosh, Pranab; Feng, Gang; Pradhan, Vivek; Aggarwal, Sudeepta; Banfield, Christopher; Peeva, Elena; Vincent, Michael S.; Beebe, Jean S.; Tarabar, Sanela 分享 收藏
Efficacy and safety of topical brepocitinib for the treatment of mild-to-moderate atopic dermatitis: a phase IIb, randomized, double-blind, vehicle-controlled, dose-ranging and parallel-group study Landis, Megan N.; Arya, Mark; Smith, Stacy; Draelos, Zoe; Usdan, Lisa; Tarabar, Sanela; Pradhan, Vivek; Aggarwal, Sudeepta; Banfield, Christopher; Peeva, Elena; Vincent, Michael S.; Sikirica, Vanja; Xenakis, Jason; Beebe, Jean S. 分享 收藏
Ritlecitinib and brepocitinib demonstrate significant improvement in scalp alopecia areata biomarkers Guttman-Yassky, Emma; Pavel, Ana B.; Diaz, Aisleen; Zhang, Ning; Del Duca, Ester; Estrada, Yeriel; King, Brett; Banerjee, Anindita; Banfield, Christopher; Cox, Lori Ann; Dowty, Martin E.; Page, Karen; Vincent, Michael S.; Zhang, Weidong; Zhu, Linda; Peeva, Elena 分享 收藏
Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study Danese, Silvio; Klopocka, Maria; Scherl, Ellen J.; Romatowski, Jacek; Allegretti, Jessica R.; Peeva, Elena; Vincent, Michael S.; Schoenbeck, Uwe; Ye, Zhan; Hassan-Zahraee, Mina; Rath, Natalie; Li, Gang; Neelakantan, Srividya; Banfield, Christopher; Lepsy, Christopher; Chandra, Deepa E.; Hung, Kenneth E. 分享 收藏
A phase 2a randomized, placebo-controlled study to evaluate the efficacy and safety of the oral Janus kinase inhibitors ritlecitinib and brepocitinib in alopecia areata: 24-week results 一项2a期随机，安慰剂对照研究，以评估口服Janus激酶抑制剂ritlecitinib和brepocitinib在斑秃中的疗效和安全性: 24周结果 King, Brett; Guttman-Yassky, Emma; Peeva, Elena; Banerjee, Anindita; Sinclair, Rodney; Pavel, Ana B.; Zhu, Linda; Cox, Lori Ann; Craiglow, Brittany; Chen, Linda; Banfield, Christopher; Page, Karen; Zhang, Weidong; Vincent, Michael S. 分享 收藏
Oral ritlecitinib and brepocitinib in patients with Moderate to Severe Active Ulcerative Colitis: Data from the VIBRATO umbrella study Sandborn, W.; Danese, S.; Leszczyszyn, J.; Romatowski, J.; Altintas, E.; Peeva, E.; Vincent, M.; Reddy, P.; Banfield, C.; Banerjee, A.; Gale, J.; Hung, K. 分享 收藏
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A phase I, randomized, double-blind study to assess the safety, tolerability and efficacy of the topical RORC2 inverse agonist PF-06763809 in participants with mild-to-moderate plaque psoriasis Berstein, G.; Zhang, Y.; Berger, Z.; Kieras, E.; Li, G.; Samuel, A.; Yeoh, T.; Dowty, H.; Beaumont, K.; Wigger-Alberti, W.; von Mackensen, Y.; Kroencke, U.; Hamscho, R.; Garcet, S.; Krueger, J. G.; Banfield, C.; Oemar, B. 分享 收藏
Efficacy and Safety of PF-06651600 (Ritlecitinib), a Novel JAK3/TEC Inhibitor, in Patients With Moderate-to-Severe Rheumatoid Arthritis and an Inadequate Response to Methotrexate Robinson, Michael F.; Damjanov, Nemanja; Stamenkovic, Bojana; Radunovic, Goran; Kivitz, Alan; Cox, Lori; Manukyan, Zorayr; Banfield, Christopher; Saunders, Michael; Chandra, Deepa; Vincent, Michael S.; Mancuso, Jessica; Peeva, Elena; Beebe, Jean S. 分享 收藏
Molecular and Cellular Responses to the TYK2/JAK1 Inhibitor PF-06700841 Reveal Reduction of Skin Inflammation in Plaque Psoriasis Page, Karen M.; Suarez-Farinas, Mayte; Suprun, Maria; Zhang, Weidong; Garcet, Sandra; Fuentes-Duculan, Judilyn; Li, Xuan; Scaramozza, Matthew; Kieras, Elizabeth; Banfield, Christopher; Clark, James D.; Fensome, Andrew; Krueger, James G.; Peeva, Elena 分享 收藏
First-in-human, randomized dose-escalation study of the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of PF-06480605 in healthy subjects Banfield, Christopher; Rudin, Dan; Bhattacharya, Indranil; Goteti, Kosalaram; Li, Gang; Hassan-Zahraee, Mina; Brown, Lisa S.; Hung, Kenneth E.; Pawlak, Sylvester; Lepsy, Christopher 分享 收藏
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