Robert J. Fletterick - Publications, H-index & Citations

Robert J. Fletterick

university of california san francisco

85H指数

287论文数

2.3W被引数

收录论文 68

发表时间

Phosphorylation and intramolecular stabilization of the ligand binding domain in the nuclear receptor steroidogenic factor 1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

104

OAAI

Desclozeaux, M; Krylova, IN; Horn, F; Fletterick, RJ; Ingraham, HA

Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite

CELL CHEMICAL BIOLOGY

IF7.2

2019-05-01

OAAI

Bruning, John M.; Wang, Yan; Oltrabella, Francesca; Tian, Boxue; Kholodar, Svetlana A.; Liu, Harrison; Bhattacharya, Paulomi; Guo, Su; Holton, James M.; Fletterick, Robert J.; Jacobson, Matthew P.; England, Pamela M.

LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival

NATURE COMMUNICATIONS

IF15.7

2018-10-10

OAAI

Bayrer, James R.; Wang, Hongtao; Nattiv, Roy; Suzawa, Miyuki; Escusa, Hazel S.; Fletterick, Robert J.; Klein, Ophir D.; Moore, David D.; Ingraham, Holly A.

Development of 5N-Bicalutamide, a High-Affinity Reversible Covalent Antiandrogen

ACS CHEMICAL BIOLOGY

IF3.8

2017-11-02

PREAI

Cortez, Felipe de Jesus; Phuong Nguyen; Truillet, Charles; Tian, Boxue; Kuchenbecker, Kristopher M.; Evans, Michael J.; Webb, Paul; Jacobson, Matthew P.; Fletterick, Robert J.; England, Pamela M.

A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

ELIFE

IF0

2015-12-11

OAAI

Suzawa, Miyuki; Miranda, Diego A.; Ramos, Karmela A.; Ang, Kenny K-H; Faivre, Emily J.; Wilson, Christopher G.; Caboni, Laura; Arkin, Michelle R.; Kim, Yeong-Sang; Fletterick, Robert J.; Diaz, Aaron; Schneekloth, John S., Jr.; Ingraham, Holly A.

Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2015-12-01

OAAI

Sablin, Elena P.; Blind, Raymond D.; Uthayaruban, Rubatharshini; Chiu, Hsiu-Ju; Deacon, Ashley M.; Das, Debanu; Ingraham, Holly A.; Fletterick, Robert J.

Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-03-30

OAAI

Hayashi, Yohei; Caboni, Laura; Das, Debanu; Yumoto, Fumiaki; Clayton, Thomas; Deller, Marc C.; Nguyen, Phuong; Farr, Carol L.; Chiu, Hsiu-Ju; Miller, Mitchell D.; Elsliger, Marc-Andre; Deacon, Ashley M.; Godzik, Adam; Lesley, Scott A.; Tomoda, Kiichiro; Conklin, Bruce R.; Wilson, Ian A.; Yamanaka, Shinya; Fletterick, Robert J.

Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism

NATURE COMMUNICATIONS

IF15.7

2015-02-17

111

OAAI

Torres, Idelisse Ortiz; Kuchenbecker, Kristopher M.; Nnadi, Chimno I.; Fletterick, Robert J.; Kelly, Mark J. S.; Fujimori, Danica Galonic

Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-02-09

OAAI

Bayrer, James R.; Mukkamala, Sridevi; Sablin, Elena P.; Webb, Paul; Fletterick, Robert J.

Advances in our structural understanding of orphan nuclear receptors 我们对孤儿核受体结构的理解进展

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2015-01-01

PREAI

Gallastegui, Nerea; Mackinnon, Jonathan A. G.; Fletterick, Robert J.; Estebanez-Perpina, Eva

The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-10-06

OAAI

Blind, Raymond D.; Sablin, Elena P.; Kuchenbecker, Kristopher M.; Chiu, Hsiu-Ju; Deacon, Ashley M.; Das, Debanu; Fletterick, Robert J.; Ingraham, Holly A.

Computer Modeling of a Newly Identified THRB Gene Mutation (S350L) Associated with Resistance to Thyroid Hormone in Three Unrelated Patients

THYROID

IF6.7

2014-09-01

OAAI

Nagavalli, Sravanthi; Fletterick, Robert J.; Ford, George; Boston, Bruce A.; Gianoukakis, Andrew G.

Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-06-10

OAAI

Bhattacharya, Suparna; Lou, Xiaohua; Hwang, Peter; Rajashankar, Kanagalaghatta R.; Wang, Xiaoping; Gustafsson, Jan-Ake; Fletterick, Robert J.; Jacobson, Raymond H.; Webb, Paul

Incidental Identification of a Thyroid Hormone Receptor Beta (THRB) Gene Variant in a Family with Autoimmune Thyroid Disease

THYROID

IF6.7

2013-12-01

OAAI

Larsen, Caecilie C.; Dumitrescu, Alexandra; Guerra-Argueero, Laura M.; Gallego-Suarez, Cecillia; Vazquez-Mellado, Alberto; Vinogradova, Maia; Fletterick, Robert; Refetoff, Samuel; Weiss, Roy E.

Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-07-01

OAAI

Benod, Cindy; Carlsson, Jens; Uthayaruban, Rubatharshini; Hwang, Peter; Irwin, John J.; Doak, Allison K.; Shoichet, Brian K.; Sablin, Elena P.; Fletterick, Robert J.

John D. Baxter, MD, 1940-2011 In Memoriam

THYROID

IF6.7

2012-02-01

PREAI

Scanlan, Thomas S.; Fletterick, Robert J.

A conserved surface on the ligand binding domain of nuclear receptors for allosteric control

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2012-01-01

PREAI

Buzon, Victor; Carbo, Laia R.; Estruch, Sara B.; Fletterick, Robert J.; Estebanez-Perpina, Eva

Structural basis of coactivation of liver receptor homolog-1 by β-catenin

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-12-20

OAAI

Yumoto, Fumiaki; Phuong Nguyen; Sablin, Elena P.; Baxter, John D.; Webb, Paul; Fletterick, Robert J.

Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-09-26

114

OAAI

Benod, Cindy; Vinogradova, Maia V.; Jouravel, Natalia; Kim, Grace E.; Fletterick, Robert J.; Sablin, Elena P.

Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-07-05

128

OAAI

De Leon, Johanny Tonos; Iwai, Aki; Feau, Clementine; Garcia, Yenni; Balsiger, Heather A.; Storer, Cheryl L.; Suro, Raquel M.; Garza, Kristine M.; Lee, Sunmin; Kim, Yeong Sang; Chen, Yu; Ning, Yang-Min; Riggs, Daniel L.; Fletterick, Robert J.; Guy, R. Kiplin; Trepel, Jane B.; Neckers, Leonard M.; Cox, Marc B.

研究方向